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Re-challenge treatment of small-molecular inhibitors in NSCLC patients beyond progression

  
@article{JTD589,
	author = {Lingli Tu and Lan Sun},
	title = {Re-challenge treatment of small-molecular inhibitors in NSCLC patients beyond progression},
	journal = {Journal of Thoracic Disease},
	volume = {4},
	number = {6},
	year = {2012},
	keywords = {},
	abstract = {In the past ten years, small-molecular inhibitors have presented exclusive promise on non-small cell lung cancer (NSCLC) and long-term survival has been achieved (1,2). However, drug resistance is still a huge blockade for clinical practice. Some recent studies greatly encouraged clinical physicians due to favorable outcomes obtained in NSCLC patients with disease progression (PD) after re-challenge treatment of small-molecular inhibitors such as crizitinib, gefitinib and erlotinib (3,4). It provided important evidences to guide the standard of personal treatment. However, there is still a long way to go.},
	issn = {2077-6624},	url = {https://jtd.amegroups.org/article/view/589}
}