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Clinicopathologic correlates of postoperative N1 or N2 nodal upstaging in non-small cell lung cancer

  
@article{JTD6371,
	author = {Youngkyu Moon and Kyo Young Lee and Kyung Soo Kim and Jae Kil Park},
	title = {Clinicopathologic correlates of postoperative N1 or N2 nodal upstaging in non-small cell lung cancer},
	journal = {Journal of Thoracic Disease},
	volume = {8},
	number = {1},
	year = {2016},
	keywords = {},
	abstract = {Background: Clinical and pathologic determinations of lymph node staging are critical in the treatment of lung cancer. However, up- or downstaging of nodal status frequently is necessitated by postsurgical findings. This study was conducted to evaluate clinicopathologic features that impact nodal upstaging in patients staged primarily via positron emission tomography/computed tomography (PET/CT) and chest CT prior to surgery.
Methods: Between years 2011 and 2014, 634 patients underwent surgical treatment for non-small cell lung cancer (NSCLC) at our institution. Excluding 37 patients (given induction chemotherapy), 103 patients pathologically staged as N1 or N2 NSCLC. Nodal upstaging patients were classified into group A and non-upstaging patients into group B. We compared clinical characteristics and pathological results of group A with group B.
Results: Ultimately, 59 patients (57.3%) were assigned to group A and 44 patients (42.7%) to group B. Patients in group A (vs. group B) were significantly younger (61.6 vs. 68.4 years; P},
	issn = {2077-6624},	url = {https://jtd.amegroups.org/article/view/6371}
}