@article{JTD7045,
author = {Patrick M. Honore and Rita Jacobs and Inne Hendrickx and Elisabeth De Waele and Herbert D. Spapen},
title = {Lactate: the Black Peter in high-risk gastrointestinal surgery patients},
journal = {Journal of Thoracic Disease},
volume = {8},
number = {6},
year = {2016},
keywords = {},
abstract = {Lactate arises from metabolisation of glucose to pyruvate. Pyruvate either is transformed to or from lactate in the cytosol or converted by pyruvate dehydrogenase in mitochondria to acetyl coenzyme A which enters the Krebs cycle to produce energy for cellular metabolism. Any switch to anaerobic metabolism will reduce activity of the highly oxygen-dependent Krebs cycle and shunt “redundant” pyruvate towards lactate (1).},
issn = {2077-6624}, url = {https://jtd.amegroups.org/article/view/7045}
}