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Visceral pleural invasion in lung adenocarcinoma ≤3 cm with ground-glass opacity: a clinical, pathological and radiological study

   
@article{JTD7841,
	author = {Li-Lan Zhao and Hui-Kang Xie and Li-Ping Zhang and Jun-Yan Zha and Fang-Yu Zhou and Ge-Ning Jiang and Chang Chen},
	title = {Visceral pleural invasion in lung adenocarcinoma ≤3 cm with ground-glass opacity: a clinical, pathological and radiological study},
	journal = {Journal of Thoracic Disease},
	volume = {8},
	number = {7},
	year = {2016},
	keywords = {},
	abstract = {Background: Visceral pleural invasion (VPI) had been demonstrated as an aggressive sign in non-small cell lung cancers (NSCLC). However, its incidence and clinical relevance in early lung cancer showing ground glass nodules (GGNs) has not been clarified.
Methods: All consecutive surgically treated patients with solitary GGNs between 2009 and 2013 were reviewed retrospectively. Inclusion criteria were defined as lesions ≤3 cm with pleura abutting on computed tomography (CT) scan and pathologically confirmed NSCLC.
Results: Out of 156 enrolled patients, 38 had pathologically confirmed VPI. The incidence of VPI was 41.5% (27/65) if the tumor diameter was larger than 2.0 cm and 14.3% (13/91) if diameter was smaller than 2.0 cm (P2 cm) GGNs. The radiographic findings of nodule abutment or a pleural tag did not reliably predict or exclude VPI. In patients with GGNs, a low rate of PL2 invasion may be observed.},
	issn = {2077-6624},	url = {https://jtd.amegroups.org/article/view/7841}
}