@article{JTD8154,
author = {Luca Liberale and Fabrizio Montecucco},
title = {Therapeutic hypothermia in ST elevation myocardial infarction (STEMI): a long way to go},
journal = {Journal of Thoracic Disease},
volume = {8},
number = {8},
year = {2016},
keywords = {},
abstract = {Post-ischemic reperfusion injury is mediated by infiltration and activation of circulating inflammatory cell subsets (i.e., neutrophils) that early entered the area-at-risk and release proteases and reactive oxygen species (ROS) (1-3). A recent study demonstrated that during recovery neutrophil infiltration might be protective, thus favoring a proper scar formation and potentially preventing negative left ventricle remodeling (4). Given this pathophysiological complexity, some selective drugs targeting these cells failed to induce a clear benefit on mortality and post-ischemic heart failure development in experimental models (2,5).},
issn = {2077-6624}, url = {https://jtd.amegroups.org/article/view/8154}
}