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Prognostic significance of CT-emphysema score in patients with advanced squamous cell lung cancer

  
@article{JTD8416,
	author = {Young Saing Kim and Eun Young Kim and Hee Kyung Ahn and Eun Kyung Cho and Yu Mi Jeong and Jeong Ho Kim},
	title = {Prognostic significance of CT-emphysema score in patients with advanced squamous cell lung cancer},
	journal = {Journal of Thoracic Disease},
	volume = {8},
	number = {8},
	year = {2016},
	keywords = {},
	abstract = {Background: Although emphysema is a known independent risk factor of lung cancer, no study has addressed the prognostic impact of computed tomography (CT)-emphysema score in advanced stage lung cancer. 
Methods: For 84 consecutive patients with stage IIIB and IV squamous cell lung cancer that underwent palliative chemotherapy, severity of emphysema was semi-quantitatively scored using baseline chest CT images according to the Goddard scoring system (possible scores range, 0–24). The cutoff of high CT-emphysema score was determined using the maximum chi-squared test and the prognostic significance of the high CT-emphysema score was evaluated using Kaplan-Meier analysis and Cox proportional hazards analysis. 
Results: The median CT-emphysema score was 5(range, 0–22). Patients with a high CT-emphysema score (≥4) tended to have poorer overall survival (OS) (median: 6.3 vs. 13.7 months) than those with a score of },
	issn = {2077-6624},	url = {https://jtd.amegroups.org/article/view/8416}
}