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Quantitative computed tomography: what does airway obstruction look-like?

   
@article{JTD9141,
	author = {Maria Kallieri and Andriana I. Papaioannou and Konstantinos Kostikas and Petros Bakakos and Stelios Loukides},
	title = {Quantitative computed tomography: what does airway obstruction look-like?},
	journal = {Journal of Thoracic Disease},
	volume = {8},
	number = {9},
	year = {2016},
	keywords = {},
	abstract = {Both COPD and asthma are heterogeneous diseases, characterized by airway obstruction and chronic airway inflammation (1). Small airway obstruction is present in both diseases, although there is a lack of accurate and reproducible measures of small airway function suitable to be used in clinical practice (1,2). Spirometry is the most widely used non-invasive test of pulmonary function and provides an assessment of lung function and an objective method for following disease progression or improvement and therapeutic response over time (3). However, FEV1 mainly assesses large airways, providing only limited information regarding airway remodeling, small airway obstruction, air trapping and emphysema (4). Although the presence of a post-bronchodilator FEV1/FVC },
	issn = {2077-6624},	url = {https://jtd.amegroups.org/article/view/9141}
}