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Primary pulmonary chondrosarcoma and a fast-growing mass that accidentally mimicked teratoma

  
@article{JTD9550,
	author = {Jingjin Jiang and Qian Shen and Wei Ding and Jianying Zhou},
	title = {Primary pulmonary chondrosarcoma and a fast-growing mass that accidentally mimicked teratoma},
	journal = {Journal of Thoracic Disease},
	volume = {8},
	number = {9},
	year = {2016},
	keywords = {},
	abstract = {Primary pulmonary chondrosarcoma is a rare neoplasm that usually grows slowly, metastasizes late, and responds well to excision when localized. Herein, we present a 59-year-old man who manifested with hemoptysis, cough and dyspnea with a hemithorax mass. A chest computed tomography scan demonstrated a fast-growing mass in the right upper lobe, and the enhancement was partially heterogeneous. Bronchoscopy revealed a hemorrhagic neoplasm in the right upper bronchus. A bronchoscopy biopsy specimen revealed a variety of tissues, including mucoid cartilage, fibers, respiratory epithelium and squamous epithelium. Because malignancy was suspected, the patient underwent a right upper sleeve lobectomy with mediastinal lymphadenectomy. Macroscopically, we observed a firm white mass 9.5 cm in diameter with a central area of necrosis. Histopathology revealed neoplastic chondrocytes with enlarged and hyperchromatic nuclei in the myxoid matrix. The tumors were positive for S-100. The patient was diagnosed with tracheobronchial myxoid chondrosarcoma. Lymph node dissection indicated no metastasis. The tumor grows slowly in the initial symptom-free phase when localized. Then, a symptomatic phase ensues, during which the tumor progresses rapidly. The patient displayed pulmonary and subcutaneous skull metastases eight months after operation and was treated with adriamycin and ifosfamide chemotherapy.},
	issn = {2077-6624},	url = {https://jtd.amegroups.org/article/view/9550}
}