@article{JTD9955,
author = {Enwu Xu and Xuanwei Yu and Qian Zeng and Guibin Qiao and Yiwen Xuan and Yong Tang and Qihang Zhu and Jianxing He},
title = {Functional role of lncRNA DB327252 in lung cancer},
journal = {Journal of Thoracic Disease},
volume = {8},
number = {10},
year = {2016},
keywords = {},
abstract = {Background: Lung cancer becomes a concerning health issue and is considered one of the most deadly cancers in the worldwide. Most recently, long non-coding RNAs (lncRNAs) are newfound non-coding RNAs that are thought as one of the major players in a range of biological processes of human diseases. Although lncRNAs are involved in numerous cancer types, the precise understandings of lncRNAs’ functional roles and mechanisms in lung cancer are limited. In this study, we looked for lung cancer related lncRNAs.
Methods: The quantitative reverse transcriptase polymerase chain reaction (qRT-PCR) technique was utilized to investigate the lncRNA DB327252 expression in 91 paired clinical lung cancer tissues and related cell lines. Moreover, its biological functions were also evaluated in the development of lung cancer.
Results: The results indicated that the expression of DB327252 was up-regulated in lung cancer tissues compared to the cancer-adjacent normal tissues (P},
issn = {2077-6624}, url = {https://jtd.amegroups.org/article/view/9955}
}