Vol 17, No 9 (September 30, 2025): Journal of Thoracic Disease

Editorial

Use of long-term inhaled antibiotics and macrolides: insights from the four global bronchiectasis registries
Timothy Aksamit, Wei-Jie Guan, Miguel-Angel Martinez-Garcia
Journal of Thoracic Disease  
2025;
17
(9)
:6367-6370
.
Gliding the blade through a breathing space: a non-intubated approach to tracheal and carinal surgery
Haobo Ma, Jiapeng Huang
Journal of Thoracic Disease  
2025;
17
(9)
:6371-6373
.

Original Article

Low-intensity pulsed ultrasound in acute multiple rib fracture—a prospective analysis, randomized controlled trial and pilot study
Junseok Kim, Songam Lee, Michael Ji, Dongkyu Kim, Hyeongju Moon, Woosurng Lee
Journal of Thoracic Disease  
2025;
17
(9)
:6374-6389
.
Global trends in research on radiofrequency ablation for lung cancer: a bibliometric and visualization analysis (2008–2024)
Longjun Huang, Wenjuan He, Jian Zheng, Yong Guo
Journal of Thoracic Disease  
2025;
17
(9)
:6390-6403
.
Impact of early acute kidney injury on 30-day mortality in intensive care unit patients with chronic obstructive pulmonary disease: a retrospective study using MIMIC-IV
Chuntian Chi, Jian Zhou, Sicong Hou
Journal of Thoracic Disease  
2025;
17
(9)
:6404-6415
.
Heart support crossroads: aortic Impella 5.5 implantation compared to conventional axillary approach in combined use of extracorporeal membrane oxygenation and Impella (ECMELLA) setting
Dejan Radakovic, Stepan Ekaterinichev, Kiril Penov†, Mohamed Hassan, Seymur Karimli, Nodir Madrahimov, Ivan Aleksic, Khaled Hamouda
Journal of Thoracic Disease  
2025;
17
(9)
:6416-6424
.
Risk factors of delayed extubation after esophagectomy in the surgical intensive care unit
An Shi, Jianli Wang, Chenghao Zhu, Hui Li, Jianxiao Chen, Tianyi Ai, Zhiqiang Shi, Jiajia Tang, Mingli Zhu
Journal of Thoracic Disease  
2025;
17
(9)
:6425-6434
.
Management and outcomes of acquired benign tracheoesophageal fistula: a single-centre experience of 58 cases
Maciej T. Pawlica, Jan Filipowicz, Zuzanna Gabrysz, Mateusz Gadzala, Bartosz Brzezinski, Maria Konkol, Dominika Groth, Mikolaj Lewandowski, Wojciech Grabczan, Krzysztof Karus, Marcin M. Cackowski, Michal Dziedzic, Dariusz A. Dziedzic, Tadeusz M. Orlowski
Journal of Thoracic Disease  
2025;
17
(9)
:6435-6442
.
Predicting severe community-acquired pneumonia in adults: a machine learning approach using C-reactive protein to albumin ratio
Meng Wang, Yongyi Wang, Xiaoqun Hou, Wenxin Sun
Journal of Thoracic Disease  
2025;
17
(9)
:6443-6450
.
Survival of patients with node-negative lung cancer and chest wall invasion
Anupama Singh, Ashley L. Deeb, Camille Mathey-Andrews, Miles McAllister, Alexandra L. Potter, Emanuele Mazzola, Yue Xie, Chi-Fu Jeffrey Yang, Paula Ugalde Figueroa
Journal of Thoracic Disease  
2025;
17
(9)
:6451-6460
.
Integrative analysis of programmed cell death pathways reveals prognostic biomarkers and immune infiltration signatures in coronary artery disease
Jinjin Liu, Xiao Liang, Luqin Yan, Xiaowei Huo, Fan Hong
Journal of Thoracic Disease  
2025;
17
(9)
:6461-6483
.
Lung cancer clusters and air pollution exposure in Wayne County, Michigan: an autoregressive distributed lag model
Qiong Zhang, Sue C. Grady, Shangrui Zhu, Carl P. Wilson, Yichu Wang, Xuan Ma, Hollis Hutchings, Laila Poisson, Ikenna C. Okereke
Journal of Thoracic Disease  
2025;
17
(9)
:6484-6495
.
Impact of ventilation strategy on recurrence patterns after pneumothorax surgery: a stratified analysis by lung dystrophy
Younggi Jung, Eunjue Yi, Sungho Lee, Jae Ho Chung
Journal of Thoracic Disease  
2025;
17
(9)
:6496-6507
.
Identification of disease subtypes associated with prognosis in patients with intermediate-high-risk pulmonary embolism based on hierarchical cluster analysis
Lihui Zhang, Xincai Wang, Xiaobin Pan, Shujuan Zhang, Songchang Shi, Wei Lin
Journal of Thoracic Disease  
2025;
17
(9)
:6508-6515
.
Holistic integrative analysis of circulatory parameters: breath-by-breath analysis for circulatory parameters in subjects without obstructive sleep apnea
Jia-Hao Chen, Xing-Guo Sun, Jiang Huang, Ben Xie, Fan Xu, Meng-Jun Xiang, Zeng-Fei Zhang, Qing-Qing Zhou, Chao Shi, Yan-Fang Zhang, Ji-Nan Wang, Fang Liu, You-Hong Xie
Journal of Thoracic Disease  
2025;
17
(9)
:6516-6529
.
Identifying risk factors and pathogens in postoperative pneumonia after lung surgery for cancer: a retrospective cohort study
Veronica Maria Giudici, Debora Brascia, Giuseppe Mangiameli, Emanuele Voulaz, Edoardo Bottoni, Alessandro Crepaldi, Emanuela Re Cecconi, Matilde Luppichini, Giorgio Maria Ferraroli, Alberto Testori, Marco Alloisio, Anna Stainer, Umberto Cariboni, Stefano Aliberti, Giuseppe Marulli
Journal of Thoracic Disease  
2025;
17
(9)
:6530-6541
.
Comparison of the short-term efficacy and safety of surgical operation of neoadjuvant sintilimab and camrelizumab, both in combination with chemotherapy in the treatment of resectable non-small cell lung cancer: a single-center retrospective cohort study
Xin Yao, Jialing Jiang, Hongtao Duan, Zhaoyang Wang, Guanglin Liu, Ying Sun, Chao Wang, Xiaolong Yan
Journal of Thoracic Disease  
2025;
17
(9)
:6542-6559
.
The impact of the toll-like receptor 1 (TLR1) variation rs5743557 on tuberculosis susceptibility in the Thai population
Chanyapak Saengchart, Nuttida Nimitsurachat, Weeraya Phaisal, Kamon Kawkitinarong, Pajaree Chariyavilaskul, Monpat Chamnanphon, Sasiwimol Ubolyam, Yamaratee Jaisin, Papavee Samatiwat, Punyabhorn Rattanacheeworn
Journal of Thoracic Disease  
2025;
17
(9)
:6560-6568
.
Potassium and survival outcomes in asthma patients: evidence from a retrospective cohort study
Congyi Xie, Shuwen Yang, Jinzhan Chen, Ning Zhang
Journal of Thoracic Disease  
2025;
17
(9)
:6569-6580
.
Disease burden and changing trend of tracheal, bronchus, and lung cancer attributable to tobacco, globally and in China, the USA, the Russian Federation, and India, 1990–2021
Shoucai Hu, Lingling Zhang, Linchong Ma, Chenglong Yang, Haotian Ma, Yancheng Tao, Fu Li, Gawei Hu, Qingxin Li
Journal of Thoracic Disease  
2025;
17
(9)
:6581-6596
.
Air leakage is a strong risk factor for pneumonia-related acute respiratory distress syndrome
Yuan Yuan, Chunting Wang, Huadong Zhu, Yan Li
Journal of Thoracic Disease  
2025;
17
(9)
:6597-6607
.
4L lymph node dissection in non-small cell lung cancer: an updated systematic review and subgroup meta-analysis
Grzegorz M. Gryszko, Marcin M. Cackowski, Sylwia A. Kolpaczynska, Tadeusz M. Orlowski, Dariusz A. Dziedzic
Journal of Thoracic Disease  
2025;
17
(9)
:6608-6621
.
The efficacy and adverse reactions of minocycline against Mycoplasma pneumoniae pneumonia: a systematic review and meta-analysis
Xiaoli Li, Yuqing Wang, Yuhua Zhao, Yahui Wu, Wei Qin, Fang Liu
Journal of Thoracic Disease  
2025;
17
(9)
:6622-6631
.
Second acute exacerbation of fibrotic hypersensitivity pneumonitis and idiopathic pulmonary fibrosis
Sanshiro Haga, Ryo Okuda, Eri Hagiwara, Taichi Kaneko, Yoichi Tagami, Akimasa Sekine, Tomohisa Baba, Tomoe Sawazumi, Tamiko Takemura, Takashi Ogura
Journal of Thoracic Disease  
2025;
17
(9)
:6632-6640
.
Association of early ondansetron use with 30-day mortality in patients with acute respiratory distress syndrome: a retrospective cohort study
Qian Ji, Hao Jiang
Journal of Thoracic Disease  
2025;
17
(9)
:6641-6651
.
Endobronchial ultrasound diagnostic yield for sarcoidosis in hilar vs. mediastinal lymph nodes
Naeman Mahmood, Steven Wolf, Raj Dash, Xiaofei Wang, Scott L. Shofer, Coral X. Giovacchini, Michael Dorry, Hakim Azfar Ali, Kamran Mahmood, Momen M. Wahidi
Journal of Thoracic Disease  
2025;
17
(9)
:6652-6660
.
Incidence and risk factors of postoperative pulmonary complications following esophageal cancer surgery: a single-center retrospective study
Jie Huang, Wangzheqi Zhang, Tong Wang, Haiwen Wang, Yimin Zhang, Yalin Zhu, Xiaoming Deng, Wen Xu, Jiafeng Wang
Journal of Thoracic Disease  
2025;
17
(9)
:6661-6672
.
USP7-mediated stabilization of CXCL3 aggravates inflammation in models of acute lung injury
Haijun Lv, Weiwei Wu, Yun Sima, Zijing Guo, Jia Zhu, Yuping Shen, Ting Mao
Journal of Thoracic Disease  
2025;
17
(9)
:6673-6688
.
Holistic integrative analysis of circulatory parameters: effects of CPAP titration in patients with obstructive sleep apnea
Jia-Hao Chen, Xing-Guo Sun, Meng-Jun Xiang, Zeng-Fei Zhang, Jiang Huang, Ben Xie, Fan Xu, Qing-Qing Zhou, Ji-Nan Wang, Yan-Fang Zhang, Chao Shi, Fang Liu, You-Hong Xie
Journal of Thoracic Disease  
2025;
17
(9)
:6689-6700
.
Ten-year follow-up outcomes of resected stage II non-small cell lung cancer patients
Wenrui Sun, Di Li, Yueren Yan, Han Han, Jinsong Bai, Zelin Ma, Fangqiu Fu, Yang Zhang, Haiquan Chen
Journal of Thoracic Disease  
2025;
17
(9)
:6701-6710
.
Development and internal validation of a nomogram to predict postoperative atrial fibrillation in elderly patients with lung cancer
Dongdong Wu, Hong Ye, Meiyuan Dong, Xiaohua Wu, Jianjuan Dai, Hanbo Le, Boer Yan
Journal of Thoracic Disease  
2025;
17
(9)
:6711-6723
.
The impact of high-risk zip code on receiving standard of care therapy and survival in esophageal adenocarcinoma
Megan E. Campany, Song Kim, Staci E. Beamer, Ben Seadler, Mallory L. Hunt, Mario G. Gasparri, Paul Linsky, Britton B. Donato
Journal of Thoracic Disease  
2025;
17
(9)
:6724-6734
.
Transposition of an isolated left vertebral artery during aortic arch replacement for Stanford type A aortic dissection
Fangyuan Jia, Gang Qiao, Hong Wang, Zhigang Sun, Zhidong Zhang
Journal of Thoracic Disease  
2025;
17
(9)
:6735-6747
.
Prognostic factors and outcomes of acute type A aortic dissection: a retrospective clinical study
Haochao Li, Pengfei Chen, Diming Zhao, Mingjian Chen, Liang Chen, Xiaogang Sun, Xiangyang Qian, Shaoye Wang, Zujun Chen, Liqing Wang
Journal of Thoracic Disease  
2025;
17
(9)
:6748-6758
.
Perineural invasion as a prognostic factor and the efficacy of upfront surgery for low-risk cT2/T3N0M0 esophageal squamous cell carcinoma patients
Jicheng Xiong, Simiao Lu, Shuoming Liang, Hainan Chen, Ziwei Wang, Hao Meng, Yan Miao, Qin Xie, Guangyuan Liu, Kangning Wang, Lin Peng, Qiang Fang, Wenguang Xiao, Qifeng Wang, Yongtao Han, Xuefeng Leng
Journal of Thoracic Disease  
2025;
17
(9)
:6759-6770
.
Use of metagenomic next-generation sequencing for accurate diagnosis of tuberculous pleurisy: a retrospective cohort study
Jing Liu, Huiwen Qian, Jianqiang Jin, Mingzhan Du, Changguo Wang, Jie Yu, Pei Pang, Meili Shen, Zhoufang Mei, Yaxian Shi, Ziyan Wang, Guogang Jiang, Lingchuan Guo, Chongke Zhong, Peijun Tang, Yuting Wang, Cuilin Shi, Cheng Ji
Journal of Thoracic Disease  
2025;
17
(9)
:6771-6778
.
Comparison of clinical and economic outcomes among patients undergoing lung resection using ECHELONTM 3000 Staplers versus ECHELONTM+ Staplers: a multi-institutional observational study
Stephen Fortin, Jin Hao, Mingkai Peng, Gianluca Casali, Guy Cafri, Paul Coplan, Shumin Zhang
Journal of Thoracic Disease  
2025;
17
(9)
:6779-6789
.
Longitudinal analysis of postoperative symptom clusters in patients undergoing esophageal cancer surgery
Shenghui Chang, Xiaolong Wang, Yuqin Cao, Hecheng Li, Yanxia Hu
Journal of Thoracic Disease  
2025;
17
(9)
:6790-6801
.
Immune-related cardiotoxicities predict immune checkpoint inhibitors treatment for advanced non-small cell lung cancer: a retrospective multi-center study
Hengxing Sun, Yini Huang, Hongxia Duan, Mengting Xiong, Yukun Wang, Yingyi Qin, Yanbin Kuang, Xiaoming Li, Siwan Wen, Fengming Ding, Hao Tang, Yang Chen, Junyong Zou, Feng Hu, Caicun Zhou, Changhui Wang, Fenyong Sun, Dachun Xu, Shuanshuan Xie
Journal of Thoracic Disease  
2025;
17
(9)
:6802-6814
.
Detection of malignant lung tumors using stimulated Raman histology and convolutional neural networks
Karl-Moritz Schröder, Andreas Weber, Marlene Schmid, Mohamed Hassan, Uyen-Thao Le, Severin Schmid, Bernward Passlick, Martin Werner, Birte Ohm, Peter Bronsert
Journal of Thoracic Disease  
2025;
17
(9)
:6815-6825
.
Feasibility of surgical resection for gastric cancer in the gastric conduit following esophagectomy for esophageal squamous cell carcinoma
Jia Ying Soo, Chang Yuan, Bin Li, Rong Hua, Yifeng Sun, Chunguang Li, Zhigang Li
Journal of Thoracic Disease  
2025;
17
(9)
:6826-6836
.
A study on the influencing factors of early clinical stability in patients with acute exacerbation of chronic obstructive pulmonary disease complicated by pneumonia
Li Yin, Shanna Li, Linhai Pan
Journal of Thoracic Disease  
2025;
17
(9)
:6837-6849
.
Risk and protective factors of higher-grade intrapulmonary hemorrhage in patients undergoing percutaneous computed tomography-guided microcoil localization before video-assisted thoracoscopic surgery
Yunxin Li, Yanyan Xu, Hongxiang Feng, Tongyin Zhang, Shuzhu Qin, Hongliang Sun, Zhenguo Huang
Journal of Thoracic Disease  
2025;
17
(9)
:6850-6861
.
Risk factors associated with sternal complication after lung transplantation with transverse sternotomy
Joshua T. Kim, Yudai Miyashita, Taisuke Kaiho, Nathan T. Kim, Charles Logan, Chitaru Kurihara
Journal of Thoracic Disease  
2025;
17
(9)
:6862-6872
.
Concurrent mutations in multiple tumor suppressor genes correlate with adverse prognosis in stage I lung adenocarcinoma patients
Yuan Wang, Renjie Xu, Jing Ren, Yuanjie Li, Yaoxi Chen, Li Zhang, Zhixin Qiu
Journal of Thoracic Disease  
2025;
17
(9)
:6873-6883
.
Comparison of surgery and stereotactic body radiation therapy for clinical stage I NSCLC: a propensity score-matched analysis from a single institution
Shiho Lee, O Kyu Noh
Journal of Thoracic Disease  
2025;
17
(9)
:6884-6892
.
Neoadjuvant chemoimmunotherapy versus chemoradiotherapy for non-small cell lung cancer: a comparative analysis of clinical outcomes and pathologic response
Ji Hyeon Park, Ki-Chang Lee, Sangjun Lee, Taeyoung Yun, Seung Hwan Yoon, Bubse Na, Samina Park, Hyun Joo Lee, In Kyu Park, Chang Hyun Kang, Young Tae Kim, Jaemoon Koh, Kwon Joong Na
Journal of Thoracic Disease  
2025;
17
(9)
:6893-6904
.
Outcomes of tracheostomy after cardiac surgery through median sternotomy
Ho Seong Cho, Soojin Lee
Journal of Thoracic Disease  
2025;
17
(9)
:6905-6914
.
U-shaped association between lymphocyte-to-high-density lipoprotein ratio and all-cause mortality in patients with chronic obstructive pulmonary disease: insights from a population-based cohort study
Yiming Ma, Zikun Fang, Shiwei Kang, Kun Tang, Wenjie Guo, Qi Pan, Wensen Pan, Jing Yu
Journal of Thoracic Disease  
2025;
17
(9)
:6915-6926
.
Global trends and projections of tracheal, bronchial, and lung (TBL) cancers associated with occupational exposure to diesel engine exhaust (DEE): insights from the Global Burden of Disease (GBD) 2021 Study for 1990 to 2021 and projections to 2035
Weizhen Guo, Jian Ding, Gang Cheng, Qian Xue, Di Wu, Cheng Yang, Jiabing Tong, Zegeng Li
Journal of Thoracic Disease  
2025;
17
(9)
:6927-6943
.
Assessment of cough in asthma patients attending clinic using the cough questionnaire for asthma (CQA)
Sujuan Guo, Zhicheng Yang, Min Liu, Mary S. M. Ip, Woo-Jung Song, Kian Fan Chung
Journal of Thoracic Disease  
2025;
17
(9)
:6944-6953
.
Machine learning–based model for predicting distant lymph node metastasis in esophageal cancer
Guojun Wang, Jin Wang
Journal of Thoracic Disease  
2025;
17
(9)
:6954-6970
.
Circulating tumor DNA in lung cancer: a bibliometric analysis of studies published from 2001 to 2024
Siwei Zhang, Guojie Cao, Jiayi Ren, Yunyun Wang, Peng Chen
Journal of Thoracic Disease  
2025;
17
(9)
:6971-6996
.
Advancing prognostic and therapeutic prediction in lung squamous cell carcinoma through integrated multi-omics analysis and 117 machine learning combinations
Guangcai Wan, Shuang Li, Xuefeng Wu, Hongshuai Sun, Lianzhi Cui
Journal of Thoracic Disease  
2025;
17
(9)
:6997-7017
.
Thromboelastography and interleukin-6 predict postoperative negative remodeling of descending aorta in patients with type A aortic dissection
Qingsong Wu, Yue Shen, Xinfan Lin, Siying Luo, Xiaolong Ye, Linyan Chen, Liangwan Chen
Journal of Thoracic Disease  
2025;
17
(9)
:7018-7028
.
Head-to-head comparison of the diagnostic accuracy of pleural fluid, serum carcinoembryonic antigen, and their ratio for malignant pleural effusion: a systematic review and meta-analysis
Dan-Ni Yang, Yan Niu, Jian-Xun Wen, Li Yan, Ling Hai, Cheng Yan, Hong-Zhe Zhu, Su-Na Cha, Qian Yang, Wei Jiao, Wen-Qi Zheng, Zhi-De Hu, Mei-Ying Wang
Journal of Thoracic Disease  
2025;
17
(9)
:7029-7040
.
Survival prediction model for hypoxemic patients receiving post-extubation oxygen therapy after invasive ventilation: based on the MIMIC database
Yun Cao, Guijin Liang, Xiuping Huang, Zenglu Zheng, Yu Xiong
Journal of Thoracic Disease  
2025;
17
(9)
:7041-7055
.
Development of a prognostic prediction signature for idiopathic pulmonary fibrosis by integrating multiple programmed cell death-related genes and machine learning algorithms
Jingyang Sun, Rongxuan Jiang, Meng Li, Qian Zhai, Niuniu Dong, Huanhuan Dong, Guangjian Zhang, Yanpeng Zhang
Journal of Thoracic Disease  
2025;
17
(9)
:7056-7073
.
Construction and effectiveness assessment of the health education system for outpatient chronic respiratory diseases based on visualized intelligent healthcare
Qiuxuan Zeng, Huixin Huang, Qin Luo, Weixia Liao, Lanfang Zeng, Shanshan Hu
Journal of Thoracic Disease  
2025;
17
(9)
:7074-7084
.
Comparison of the difference between post-intubation tracheal stenosis and post-tracheostomy tracheal stenosis: a cross-sectional study
Xiao-Feng Liu, Fu-Yao Nan, Lei Li, Jun Teng, Heng Zou, Hong-Wu Wang, Nan Zhang
Journal of Thoracic Disease  
2025;
17
(9)
:7085-7097
.
Cardiopulmonary exercise testing-guided exercise protocols based on Holistic Integrative Physiology and Medicine theory aim to optimize glucose regulation in chronic type II diabetes mellitus patients
Ben Xie, Xing-Guo Sun, Jiang Huang, Jia-Hao Chen, Fan Xu, Meng-Jun Xiang, Zeng-Fei Zhang, Qing-Qing Zhou, Chao Shi, Yan-Fang Zhang, Ji-Nan Wang, Fang Liu, You-Hong Xie
Journal of Thoracic Disease  
2025;
17
(9)
:7098-7111
.
Predictive model for inhaled corticosteroid response in hospitalized asthma: implications for precision medicine
Dong Liu, Luna Zhao, Ye Liu, Yihao Zhang, Guizhen Lv, Yao Wang, Chao Liu, Chao Wu
Journal of Thoracic Disease  
2025;
17
(9)
:7112-7123
.
The effect of different work rate increasing rates on cardiopulmonary exercise testing in arm ergometer
Zeng-Fei Zhang, Xing-Guo Sun, Jia-Hao Chen, Fan Xu, Meng-Jun Xiang, Jiang Huang, Ben Xie, Chao Shi, Yan-Fang Zhang, Fang Liu, Lin Li, You-Hong Xie
Journal of Thoracic Disease  
2025;
17
(9)
:7124-7140
.
Exploring diagnostic gene markers and immune infiltration in idiopathic pulmonary fibrosis
Shuang Sun, Sibo Wang, Yuichi Sakairi, Giulia Maria Stella, Wei Zhao
Journal of Thoracic Disease  
2025;
17
(9)
:7141-7154
.
Intervention of traditional Chinese medicine San-Feng-Tong-Qiao-Di-Wan on allergic rhinitis: a network pharmacology and metabolomics study
Huian Chen, Yongqing Xu, Xiaolong Deng, Haoqing Chen, Guanyu Yan, Jieya Peng, Jiaying Luo
Journal of Thoracic Disease  
2025;
17
(9)
:7155-7166
.
Association of systemic inflammatory markers and tertiary lymphoid structures with pathological complete response in patients with advanced lung adenocarcinoma receiving preoperative treatment: a retrospective cohort study
Xidong Ma, Junping Sun, Mei Xie, Xugang Zhang, Xunwen Lin, Hui Deng, Aiben Huang, Fangping Ren, Yiran Liang, Jie Yao, Xinyu Bao, Xin Zhang, Nuohan Han, Yuanyong Wang, Alessandro Brunelli, Lei Pan, Xinying Xue
Journal of Thoracic Disease  
2025;
17
(9)
:7167-7179
.
Osmolality as a predictor of mortality in a community setting of heart failure population with a normal range of serum sodium: a classification and regression tree analysis
Jialin He, Yafei Ren, Yulu Zhou, Xiangzhi Yang, Wei Zhou, Jianliang Yin, Jorge Salamanca, Yao Wang, Ya Li
Journal of Thoracic Disease  
2025;
17
(9)
:7180-7193
.
Diagnostic accuracy of computer-aided detection (CAD)-derived solid component proportion and mean CT attenuation for predicting invasiveness in pulmonary part-solid nodules: a retrospective study
Xiaodong Wang, Jing Xue, Guizhou Gao, Lin Qu, Haihua Zhang, Ramsy Abdelghani, Tao Zhang
Journal of Thoracic Disease  
2025;
17
(9)
:7194-7203
.
Feasibility of intraoperative Doppler ultrasound for intersegmental plane identification in pulmonary segmentectomy: a retrospective preliminary validation study
Jialiang Liu, Yuhui Gong, Lingyan Jiang, Giulio Maurizi, Junji Ichinose, Stefano Bongiolatti, Shiyu Shen, Haitao Ma, Haitao Huang
Journal of Thoracic Disease  
2025;
17
(9)
:7204-7211
.
PSMD11 facilitates immune escape by recruiting USP14 to modulate the deubiquitinating degradation of PD-L1 in non-small cell lung cancer
Yong Xi, Pengpeng Yang, Jing Zeng, Yundong Zhou, Akshay J. Patel, Weiyu Shen, Xiaoming Liu, Retnagowri Rajandram, Sivakumar Krishnasamy
Journal of Thoracic Disease  
2025;
17
(9)
:7212-7224
.
The potential of circITFG2 as a therapeutic target in lung squamous cell carcinoma
Dong Ou, Jin Nie, Yi Liu, Ling Zhang, Xiaowen Wang, Yongqian Chen, Hongping Wang, Ling Gong, Zhu Li, Fabrizio Marcucci, Daishun Liu
Journal of Thoracic Disease  
2025;
17
(9)
:7225-7240
.
MRPL51 expression is associated with poor prognosis and regulates lung adenocarcinoma progression via neurotensin
Qingxin Zeng, Aotian Guo, Haichuan Hu, Xingyu Zhu, Sheng Lu, Jingwei Xu, Chao Zheng, Zhengfu He
Journal of Thoracic Disease  
2025;
17
(9)
:7241-7261
.
Development and validation of an immune-related gene set (IRGS) model for prognostic and immunotherapeutic assessment in lung adenocarcinoma (LUAD)
Dongfang Li, Yuancai Xie, Jun Yan, Mengxi Wu, Dagmara Szmajda-Krygier, Jianhua Zhang, Jixian Liu
Journal of Thoracic Disease  
2025;
17
(9)
:7262-7273
.
Prediction, incidence, and outcomes of massive transfusion during lung transplantation
Ping Gao, Shui Yu, Xinchen Tao, Yu Yi, Jie Xiao, Lifang Zhang, Yejun Zhao, Yuanyuan Yao, Min Yan
Journal of Thoracic Disease  
2025;
17
(9)
:7274-7283
.

Brief Report

Endobronchial valve placement for persistent air leaks in patients with underlying lung disease: a case series from a resource-strapped county hospital
Brannen Liang, David Vasconcellos, Ching-Fei Chang
Journal of Thoracic Disease  
2025;
17
(9)
:7284-7291
.
Efficacy of a novel steerable chest tube system in a swine model of hemothorax
Maja T. Engler, Todd L. Graham, James D. Ross
Journal of Thoracic Disease  
2025;
17
(9)
:7292-7296
.
Patient Preferences in empYema treatment (PAPY-study): are we investigating relevant outcomes for patients?
Weija R. de Jonge, Josje Altenburg, Chris Dickhoff, Martijn van Dorp, Jouke T. Annema, David J. Heineman
Journal of Thoracic Disease  
2025;
17
(9)
:7297-7305
.

Study Protocol

A phase II clinical trial on the efficacy and safety of carboplatin plus nab-paclitaxel in chemotherapy-naive advanced or recurrent thymic epithelial tumors: protocol of Nab-TET
Fumiko Hayashi, Midori Matsuo, Shinnosuke Takemoto, Ryosuke Ogata, Yasuhiro Umeyama, Katsumi Nakatomi, Takaya Ikeda, Nanae Sugasaki, Seiji Doi, Takeshi Kitazaki, Kazumasa Akagi, Hiromi Tomono, Noritaka Honda, Yosuke Dotsu, Hirokazu Taniguchi, Hiroshi Gyotoku, Minoru Fukuda, Hiroshi Soda, Hiroshi Mukae
Journal of Thoracic Disease  
2025;
17
(9)
:7343-7351
.

Review Article

Evaluation of progression-free survival as a surrogate endpoint for overall survival in small cell lung cancer: a systematic review
Guo Lin, Fan Ge, Chao Yang, Ying Huang
Journal of Thoracic Disease  
2025;
17
(9)
:7352-7365
.
Precise localization techniques for small pulmonary nodules: what is next?
Chongde Pan, Weijian Deng, Yulin Zhao, Yuechun Lin, Yu Jiang, Ying Du, Hengrui Liang, Jun Liu, Fei Cui, Jianxing He
Journal of Thoracic Disease  
2025;
17
(9)
:7366-7378
.
Digital tomosynthesis for navigational bronchoscopy: a clinical practice review
Shreya Podder, Ajay Wagh, Douglas Kyle Hogarth
Journal of Thoracic Disease  
2025;
17
(9)
:7379-7389
.
Narrative review of malignant central airway obstruction: management updates
Sung Choi, Udit Chaddha
Journal of Thoracic Disease  
2025;
17
(9)
:7390-7405
.
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.
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.
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