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胸外科手术肺漏气与术中出血的诊治:基于Delphi法制定的意大利胸外科学会专家共识

肺持续性漏气和术中出血的诊治是胸外科手术中常见的挑战之一。 More >>

中国香港胸外科现状简介

中国香港的胸外科早在20世纪50年代还是一个新兴的亚专科,主要关注于非... More >>

中国台湾医疗系统与胸外科发展

中国台湾位于南海以北,距大陆东南沿海约180公里,总面积3.6万平方公里... More >>

Cough Section more

Clinical Practice Guidelines for Diagnosis and Management of Cough—Chinese Thoracic Society (CTS) Asthma Consortium

Kefang Lai, Huahao Shen, Xin Zhou, Zhongmin Qiu, Shaoxi Cai, Kewu Huang, Qiuping Wang, Changzheng... More >>

Cough frequency monitors: can they discriminate patient from environmental coughs?

Stefan T. Kulnik, Natalie M. Williams, Lalit Kalra, John Moxham, Surinder S. Birring More >>

Endorsement

Journal of Thoracic Disease is endorsed by: The International COPD Coalition

The International COPD Coalition

The China Asthma Alliance

The China Asthma Alliance

The Brazilian Society of Thoracic Surgery (SBCT)

The Brazilian Society of Thoracic Surgery (SBCT)

The Italian Society of Thoracic Surgery (SICT)

The Italian Society of Thoracic Surgery (SICT)

The Italian VATS Group

The Italian VATS Group

The Global Alliance against Chronic Respiratory Diseases (GARD)

The Global Alliance against Chronic Respiratory Diseases (GARD)

The Hong Kong Society of Endosonography

The Hong Kong Society of Endosonography

Editorial

How to determine surgical management in octogenarian patients with lung cancer?
Dohun Kim
Surgery for octogenarians: the secret is in the selection
Pietro Bertoglio, Leonardo Valentini, Marco Scarci, Peter Kestenholz, Fabrizio Minervini
Management and mindset for air leak and intraoperative bleeding in thoracic surgery
Takahiro Iida, Yoshihisa Shimada, Masaaki Sato
Is indwelling pleural catheter placement worthwhile for pleural effusion after lung resection?
Jackson Ka-Chun Leung, Ka-Yan Chiang, Macy Mei-Sze Lui
The impact of novel instrumentation in promoting uniportal video-assisted thoracoscopic surgery
Nathan J. Alcasid, Kian C. Banks, Jeffrey B. Velotta
Idiopathic tracheal stenosis and hormone receptors
Jenna Aziz, Raghav Murthy
Pulmonary transplantation—is it a long-term solution?
Sivaveera Kandasamy, Christine L. Lau, Alexander Sasha Krupnick
Patient reported outcomes in thoracic trauma—lesson learned from thoracic oncology
Michael R. Gooseman, Michael E. Cowen, Vasileios Tentzeris, Syed S. A. Qadri, Alessandro Brunelli, Cecilia Pompili

Original Article

Risk factors for mitral valve dysfunction, reoperation and death following repair of the primary mitral valve disease in children
Yixuan Cai, Na Jiang, Gang Chen, Yaping Mi, Hui Zhong, Bing Jia, Huifeng Zhang, Ming Ye
Efficacy and safety of immune checkpoint inhibitors in lung large-cell neuroendocrine carcinoma
Zheng Shi, Jingwen Wei, Manyi Xu, Zhengbo Song
Prevalence, diagnosis, and treatment of chronic obstructive pulmonary disease in a hospitalized lung cancer population: a single center study
Haiyan Qu, Mengjing Zhu, Chuxiao Shan, Xuan Ji, Guijuan Ji, Wenhui Zhang, Hao Zhang, Bi Chen
Continuous intraoperative neuromonitoring of the recurrent laryngeal nerve during lung operations
Andreas Kirschbaum, Nora Jochens, David Stay, Christian Meyer, Detlef K. Bartsch
Association between Childhood Asthma Control Test scores and lung pathophysiologic indicators in longitudinal measurements
Xiaoxing Cui, Xiaojian Zhou, Zhen Li, Yanbo Teng, Lili Lin, Qian Wang, Jianguo Hong, Yan Lin, Marilyn S. Black, Michael H. Bergin, Junfeng Zhang
Comparison of uniport versus triport thoracoscopic single or combined basal segmentectomy for stage IA lung cancer
Zhangyi Dai, Yiming Li, Xingqi Mi, Zhenyu Yang, Jiayi Gao, Chengwu Liu, Jiandong Mei, Lunxu Liu, Qiang Pu
Evaluation of automated sample preparation system for lymph node sampling
Jennifer D. Duke, Charles D. Sturgis, Christopher Hartley, Morgan Bailey, Michal Reid, Ryan Kern, Alex Bluestone, Hariharan Subramanian, Janani Reisenauer
High level of C-reactive protein as a predictive factor for immune-related adverse events of immune checkpoint inhibitors in non-small cell lung cancer: a retrospective study
Ren Onodera, Shinji Chiba, Satoru Nihei, Itaru Fujimura, Masachika Akiyama, Yu Utsumi, Hiromi Nagashima, Kenzo Kudo, Makoto Maemondo
Primary clear cell adenocarcinoma of the lung: a national analysis
Arian Mansur, Zain Saleem, Alexandra L. Potter, Camille Mathey-Andrews, Priyanka Senthil, Chi-Fu Jeffrey Yang
Impact of intraoperative use of venovenous extracorporeal membrane oxygenation on the status of von Willebrand factor large multimers during single lung transplantation
Hisashi Oishi, Yoshinori Okada, Yamato Suzuki, Takashi Hirama, Yutaka Ejima, Shin-ichi Fujimaki, Shingo Sugawara, Noriyuki Okubo, Hisanori Horiuchi
Improved clinical outcomes following introduction of an attending intensivist for patients admitted to the cardiac surgical intensive care unit after valvular heart surgery: a single-center experience
Dong Jung Kim, You Kyeong Park, Kang Min Kim, Sang Yoon Kim, Joon Chul Jung, Hyoung Woo Chang, Jae Hang Lee, Jun Sung Kim, Cheong Lim, Kay-Hyun Park
Practice patterns and trends in surgical treatment for chronic lung infections: a survey from the Brazilian Society of Thoracic Surgery
Alessandro Wasum Mariani, Paula Duarte D’Ambrosio, Eserval Rocha Junior, Antero Gomes Neto, Sérgio Tadeu Lima Fortunato, Ricardo Mingarini Terra, Paulo Manuel Pêgo-Fernandes
Systematic review and meta-analysis of segmentectomy vs. lobectomy for stage IA non-small cell lung cancer
Zhangyi Dai, Jiawen Hu, Cheng Shen, Xingqi Mi, Qiang Pu
Preoperative diameters of aorta influence the remodeling after surgery for type A aortic dissection
Lanlin Zhang, Sheng Yang, Huiqiang Gao, Shangdong Xu
Effect of baseline cancer pain on the efficacy of immunotherapy in lung cancer patients
Huan Zhou, Jingwen Wei, Wei Sun, Zhengbo Song
A clinical study on the surgical treatment of simple multiple rib fractures in older adult patients
Dong Zhang, Langran Wang, Siqi Xi, Run Li, Chenbo Jiao, Qiang Zhang
Clinical outcomes of the cuff wrapping technique in the modified Bentall procedure: a propensity score-matched study
Ling-Chen Huang, Chuang Liu, Shu-Ya Fan, Yang-Xue Sun, Hong-Wei Guo
Selective coronary vein bypass graft improves outcomes of patients with right coronary artery lesion
Longsheng Dai, Wenyuan Yu, Mingxin Gao, Yang Yu
Total arch replacement versus hybrid operation for aortic arch aneurysm in elderly patients: a retrospective cohort analysis
Kyungsub Song, Yun Seok Kim, Woo Sung Jang, Suryeun Chung, Yang Hyun Cho, Dong Seop Jeong, Wook Sung Kim, Kiick Sung
Recommended first-line management of asymptomatic brain metastases from EGFR mutant and ALK positive non-small cell lung cancer varies significantly according to specialty: an international survey of clinical practice
Chin Heng Fong, Nicholas Meti, Timothy Kruser, Jessica Weiss, Zhihui Amy Liu, Hirokazu Takami, Yoshitaka Narita, Fabio Ynoe de Moraes, Archya Dasgupta, Choo Khoon Ong, James C. H. Yang, Jih Hsiang Lee, Natalya Kosyak, Nicholas Pavlakis, Paul Kongkham, Mark Doherty, Natasha B. Leighl, David B. Shultz
Occult pneumothorax in patients with blunt chest trauma: key findings on supine chest radiography
Il Hwan Park, Chang Wan Kim, Young Un Choi, Tae Wook Kang, Jihye Lim, Chun Sung Byun
Long-term survival in esophagectomy for early-stage esophageal cancer versus endoscopic resection plus additional chemoradiotherapy: a systematic review and meta-analysis
Yong Chen, Yong-Yong Wang, Lei Dai, Ming-Wu Chen
K. pneumoniae and M. smegmatis infect epithelial cells via different strategies
Renjing Hu, Lin Wan, Xiaoyun Liu, Jie Lu, Xichi Hu, Xiaoli Zhang, Min Zhang
Prognostic value of initial routine laboratory blood tests in patients with aneurysmal subarachnoid hemorrhage requiring mechanical ventilation: a retrospective cohort study
Jiayi Ren, Chong Zhang, Yahua Liu, Hongguang Han, Yong Liang, Qiyan Zhang, Simeng Li, Bryan S. Benn, Kenneth M. Nugent, Hong Qu, Guobiao Liang, Yang Bai
Serum levels of lead are associated with venous thromboembolism: a retrospective study based on the NHANES database (1999 to 2018)
Min Xiao, Dan Li, Xiaoqian Wang, Jing Zhang, Xiaoping Wang, Jiao Gao
Age and treatment disparities in survival of primary malignant cardiac tumors: an analysis of over 40 years and 500 patients
Wenmiao Wang, Li Kang, Jiaxin Zhang, Houqiang Li, Tiegang Cao, Shuai He
Selection of key genes for dilated cardiomyopathy based on machine learning algorithms and assessment of diagnostic accuracy
Tingting Chen, Xiulin Xuan, Jiajia Ni, Shuyin Jiang
Dynamic changes in macrophage subtypes during lung cancer progression and metastasis at single-cell resolution
Jian Wang, Weiqing Wu, Jinquan Xia, Lipeng Chen, Dongcheng Liu, Guangsuo Wang, Lingwei Wang, Qijun Zheng
4-phenylbutyric acid re-trafficking hERG/G572R channel protein by modulating the endoplasmic reticulum stress-associated chaperones and endoplasmic reticulum-associated degradation gene
Wen Tang, Dihui Cai, Yin Fu, Zequn Zheng, Xiaoyan Huang, Rami N. Khouzam, Yongfei Song, Jiangfang Lian
Development of a prediction model for exercise tolerance decline in the exercise assessment of patients with acute myocardial infarction undergoing percutaneous coronary intervention revascularization in the acute phase
Miaomiao Du, Xiaomei Ye, Delong Li, Congya Yang, Ruozhu Dai

Review Article on Clinical Update Sleep 20231

The neurophysiologic landscape of the sleep onset: a systematic review
Nazanin Biabani, Adam Birdseye, Sean Higgins, Alessio Delogu, Jan Rosenzweig, Zoran Cvetkovic, Alexander Nesbitt, Panagis Drakatos, Joerg Steier, Veena Kumari, David O’Regan, Ivana Rosenzweig

Disclosure

1. The series “Clinical Update Sleep 2023” was commissioned by the editorial office, Journal of Thoracic Disease without any funding or sponsorship. Joerg Steier served as the unpaid Guest Editor for the series.

Original Article

Nonintubated thoracoscopic lung resection: a 3-year experience with 285 cases in a single institution
Ke-Cheng Chen, Ya-Jung Cheng, Ming-Hui Hung, Yu-Ding Tseng, Jin-Shing Chen
Delays in the diagnosis of lung cancer
Peter M Ellis, Rachel Vandermeer
The diagnostic utility of endobronchial ultrasonography with a guide sheath and tomosynthesis images for ground glass opacity pulmonary lesions
Takehiro Izumo, Shinji Sasada, Christine Chavez, Takaaki Tsuchida
Hydration with magnesium and mannitol without furosemide prevents the nephrotoxicity induced by cisplatin and pemetrexed in patients with advanced non-small cell lung cancer
Keiko Muraki, Ryo Koyama, Yuichiro Honma, Shigehiro Yagishita, Takehito Shukuya, Rina Ohashi, Fumiyuki Takahashi, Kenji Kido, Shin-ichiro Iwakami, Shinichi Sasaki, Akihiko Iwase, Kazuhisa Takahashi
Local control rates with five-fraction stereotactic body radiotherapy for oligometastatic cancer to the lung
Deepinder Singh, Yuhchyau Chen, Mary Z. Hare, Kenneth Y. Usuki, Hong Zhang, Thomas Lundquist, Neil Joyce, Michael C. Schell, Michael T. Milano
Theoretical models of carcinogenic particle deposition and clearance in children’s lungs
Robert Sturm
A novel paradigm in the treatment of oligometastatic non-small cell lung cancer
Salma K Jabbour, Parima Daroui, Dirk Moore, Edward Licitra, Molly Gabel, Joseph Aisner
Radiotherapy for a second primary lung cancer arising post-pneumonectomy: planning considerations and clinical outcomes
Sashendra Senthi, Cornelis J. A. Haasbeek, Frank J. Lagerwaard, Wilko F. Verbakel, Patricia F. de Haan, Ben J. Slotman, Suresh Senan
Impact of metformin use on survival in locally-advanced, inoperable non-small cell lung cancer treated with definitive chemoradiation
Inaya Ahmed, Adam Ferro, Alan Cohler, John Langenfeld, Sujani G. Surakanti, Joseph Aisner, Wei Zou, Bruce G. Haffty, Salma K. Jabbour
Utility of EBUS-TBNA for diagnosis of mediastinal tuberculous lymphadenitis: a multicentre Australian experience
James Geake, Gary Hammerschlag, Phan Nguyen, Peter Wallbridge, Grant A. Jenkin, Tony M. Korman, Barton Jennings, Douglas F. Johnson, Louis B. Irving, Michael Farmer, Daniel P. Steinfort
Comparative outcomes of squamous and non-squamous non-small cell lung cancer (NSCLC) patients in phase II studies of ASA404 (DMXAA) – retrospective analysis of pooled data
Mark J McKeage, Michael B Jameson, AS1404-201 Study Group Investigators
High prevalence of gene abnormalities in young patients with lung cancer
Osamu Nagashima, Rina Ohashi, Yasuko Yoshioka, Ai Inagaki, Manabu Tajima, Yoshika Koinuma, Shin-ichiro Iwakami, Akihiko Iwase, Shinichi Sasaki, Shigeru Tominaga, Kazuhisa Takahashi
Home-based exercise: promising rehabilitation for symptom relief, improved functional status and quality of life for post-surgical lung cancer patients
Amy J. Hoffman, Ruth Ann Brintnall, Alexander von Eye, Lee W. Jones, Gordon Alderink, Lawrence H. Patzelt, Jean K. Brown
Thoracic malignant solitary fibrous tumors: A population-based study of survival
Michael T Milano, Deepinder P Singh, Hong Zhang
Differences in chemosensitivity between primary and paired metastatic lung cancer tissues: In vitro analysis based on the collagen gel droplet embedded culture drug test (CD-DST)
Masahiko Higashiyama, Jiro Okami, Jun Maeda, Toshiteru Tokunaga, Ayako Fujiwara, Ken Kodama, Fumio Imamura, Hisayuki Kobayashi
High-resolution CT findings of patients with pulmonary nocardiosis
Naoki Tsujimoto, Takeshi Saraya, Ken Kikuchi, Saori Takata, Yasuyuki Kurihara, Sayuki Hiraoka, Hiroshi Makino, Shota Yonetani, Koji Araki, Haruyuki Ishii, Hajime Takizawa, Hajime Goto
Signal stratification of autoantibody levels in serum samples and its application to the early detection of lung cancer
Graham F. Healey, Stephen Lam, Peter Boyle, Geoffrey Hamilton-Fairley, Laura J. Peek, John F. R. Robertson

Review Article

Molecular biology of lung cancer
Wendy A. Cooper, David C. L. Lam, Sandra A. O’Toole, John D. Minna
Nontuberculous mycobacterial pulmonary infections
Margaret M. Johnson, John A. Odell
Treatment of advanced non small cell lung cancer
Maria Anna Bareschino, Clorinda Schettino, Antonio Rossi, Paolo Maione, Paola Claudia Sacco, Rosario Zeppa, Cesare Gridelli
Chemotherapy advances in small-cell lung cancer
Bryan A. Chan, Jermaine I. G. Coward
Electromagnetic navigation bronchoscopy: A descriptive analysis
Steven Leong, Hong Ju, Henry Marshall, Rayleen Bowman, Ian Yang, Ann-Maree Ree, Cathy Saxon, Kwun M Fong
Targeted therapy in lung cancer: IPASS and beyond, keeping abreast of the explosion of targeted therapies for lung cancer
Peter Savas, Brett Hughes, Benjamin Solomon
Stereotactic ablative radiotherapy for stage I NSCLC: Recent advances and controversies
Suresh Senan, David A. Palma, Frank J. Lagerwaard
The anticipation and management of air leaks and residual spaces post lung resection
Michael Rolf Mueller, Beatrice A. Marzluf
Exploiting sensitization windows of opportunity in hyper and hypo-fractionated radiation therapy
Anish Prasanna, Mansoor M. Ahmed, Mohammed Mohiuddin, C. Norman Coleman
Ultrasound techniques in the evaluation of the mediastinum, part 2: mediastinal lymph node anatomy and diagnostic reach of ultrasound techniques, clinical work up of neoplastic and inflammatory mediastinal lymphadenopathy using ultrasound techniques and how to learn mediastinal endosonography
Christian Jenssen, Jouke Tabe Annema, Paul Clementsen, Xin-Wu Cui, Mathias Maximilian Borst, Christoph Frank Dietrich
Revisiting signs, strengths and weaknesses of Standard Chest Radiography in patients of Acute Dyspnea in the Emergency Department
Luciano Cardinale, Giovanni Volpicelli, Alessandro Lamorte, Jessica Martino, Andrea veltri
The continuing role of chemotherapy for advanced non-small cell lung cancer in the targeted therapy era
Zarnie Lwin, Jonathan W. Riess, David Gandara
MicroRNAs in mesothelioma: from tumour suppressors and biomarkers to therapeutic targets
Glen Reid
Pleural controversies: image guided biopsy vs. thoracoscopy for undiagnosed pleural effusions?
Giles Dixon, Duneesha de Fonseka, Nick Maskell
Preservation solutions for cardiac and pulmonary donor grafts: a review of the current literature
Nicholas Latchana, Joshua R. Peck, Bryan Whitson, Sylvester M. Black
Active-specific immunotherapy for non-small cell lung cancer
Hauke Winter, Natasja K. van den Engel, Margareta Rusan, Nina Schupp, Christian H. Poehlein, Hong Ming Hu, Rudolf A. Hatz, Walter J. Urba, Karl Walter Jauch, Bernard A. Fox, Dominik Rüttinger
Advanced imaging in COPD: insights into pulmonary pathophysiology
Stephen Milne, Gregory G. King
Advances in lung adenocarcinoma classification: a summary of the new international multidisciplinary classification system (IASLC/ATS/ERS)
Elizabeth R. Tang, Andrew M. Schreiner, Bradley B. Pua
Diagnosis and early detection of COPD using spirometry
David P. Johns, Julia A.E. Walters, E. Haydn Walters
Improving radiotherapy planning, delivery accuracy, and normal tissue sparing using cutting edge technologies
Carri K. Glide-Hurst, Indrin J. Chetty
Pediatric lung transplantation: indications and outcomes
Stephen Kirkby, Don Hayes Jr
Staging lymph node metastases from lung cancer in the mediastinum
Mario D. Terán, Malcolm V. Brock
JTD special edition ‘Hot Topics in COPD’—The microbiome in COPD
Daniel C. Chambers, Shaan L. Gellatly, Philip Hugenholtz, Philip M. Hansbro
Lung donor selection criteria
John Chaney, Yoshikazu Suzuki, Edward Cantu III, Victor van Berkel
Molecular markers to predict clinical outcome and radiation induced toxicity in lung cancer
Joshua D. Palmer, Nicholas G. Zaorsky, Matthew Witek, Bo Lu
Lung cancer screening: identifying the high risk cohort
Michael W. Marcus, Olaide Y. Raji, John K. Field
Pleural controversies: indwelling pleural catheter vs. pleurodesis for malignant pleural effusions
Marc Fortin, Alain Tremblay
New techniques for assessing response after hypofractionated radiotherapy for lung cancer
Sarah A. Mattonen, Kitty Huang, Aaron D. Ward, Suresh Senan, David A. Palma
Supportive and palliative care for lung cancer patients
Patsy Yates, Penelope Schofield, Isabella Zhao, David Currow

Case Report

First report of a novel liquid nitrogen adjustable flow spray cryotherapy (SCT) device in the bronchoscopic treatment of disease of the central tracheo-bronchial airways
Robert Browning, Scott Parrish, Saiyad Sarkar, J. Francis Turner Jr
Severe amiodarone induced pulmonary toxicity
Nicholas Nacca, Castigliano M Bhamidipati, Luke S Yuhico, Sowmya Pinnamaneni, Tamas Szombathy

Guideline

Guidelines for the diagnosis and treatment of malignant pleural mesothelioma
Nico van Zandwijk, Christopher Clarke, Douglas Henderson, A. William Musk, Kwun Fong, Anna Nowak, Robert Loeragan, Brian McCaughan, Michael Boyer, Malcolm Feigen, David Currow, Penelope Schofeild, Beth Ivimey Nick Pavlakis, Jocelyn McLean, Henry Marshall, Steven Leong, Victoria Keena, Andrew Penman

Research Highlight

Gene expression assays as prognostic and predictive markers in early stage non-small cell lung cancer
Tom Donnem, Roy M Bremnes, Lill-Tove Busund, Sigve Andersen, Francesco Pezzella

Short Communication

The sleep apnea cardiovascular endpoints (SAVE) trial: Rationale and start-up phase
R Doug McEvoy, Craig S Anderson, Nick A Antic, Baoyuan Chen, Quanying He, Emma Heeley, Shaoguang Huang, Yining Huang, Jiguang Wang, Nanshan Zhong

Circulating Tumor Cells

Detection methods of circulating tumor cells
Klaus Pantel, Catherine Alix-Panabières

Original Article

Suppressive oligonucleotides inhibit inflammation in a murine model of mechanical ventilator induced lung injury
Julia Scheiermann, Dennis M. Klinman
Five-year update on the mouse model of orthotopic lung transplantation: Scientific uses, tricks of the trade, and tips for success
Xue Lin, Wenjun Li, Jiaming Lai, Mikio Okazaki, Seiichiro Sugimoto, Sumiharu Yamamoto, Xingan Wang, Andrew E. Gelman, Daniel Kreisel, Alexander Sasha Krupnick
A pooled analysis of advanced nonsquamous non-small cell lung cancer patients with stable treated brain metastases in two phase II trials receiving bevacizumab and pemetrexed as second-line therapy
Matthew A. Gubens, Jody C. Chuang, Wallace Akerley, Corey J. Langer, Christelle Clément- Duchêne, Melanie San Pedro-Salcedo, A. Dimitrios Colevas, Konstantin Dragnev, Mark A. Socinski, Heather A. Wakelee
Pleurodesis: a comparison of two sclerosing agents for pleural effusions in Mozambique
Ivo Figueiredo, Anilsa Cossa, Anila Hassane, José Sousa, Joaquim Pondo, João Teixeira, Kevan Akrami, Susannah K. Graves, Atul Malhotra, Elizabete A. Nunes

Review Article

Atypical antibody responses to influenza
Dalton Hermans, Richard J. Webby, Sook-San Wong
What can individuals do to reduce personal health risks from air pollution?
Robert Laumbach, Qingyu Meng, Howard Kipen
The role of rotors in atrial fibrillation
David E. Krummen, Vijay Swarup, Sanjiv M. Narayan
Current outcomes of off-pump versus on-pump coronary artery bypass grafting: evidence from randomized controlled trials
Daniel Fudulu, Umberto Benedetto, Gustavo Guida Pecchinenda, Pierpaolo Chivasso, Vito Domenico Bruno, Filippo Rapetto, Alan Bryan, Gianni Davide Angelini
Staging lymph node metastases from lung cancer in the mediastinum
Mario D. Terán, Malcolm V. Brock
Improving radiotherapy planning, delivery accuracy, and normal tissue sparing using cutting edge technologies
Carri K. Glide-Hurst, Indrin J. Chetty
Esophageal cancer: staging system and guidelines for staging and treatment
Mark F. Berry
Implementing the new IASLC/ATS/ERS classification of lung adenocarcinomas: results from international and Chinese cohorts
Ming-Ching Lee, Kyuichi Kadota, Daniel Buitrago, David R. Jones, Prasad S. Adusumilli
Premature menopause in young breast cancer: effects on quality of life and treatment interventions
Shoshana M. Rosenberg, Ann H. Partridge
Strategies for the acquisition of transcriptional and epigenetic information in single cells
Guang Li, Elda Dzilic, Nick Flores, Alice Shieh, Sean M. Wu
The role of transforming growth factor (TGF)-β in the infarcted myocardium
Nikolaos G. Frangogiannis
Utility of cardiac magnetic resonance for evaluation of mitral regurgitation prior to mitral valve surgery
Neil K. Mehta, Jiwon Kim, Jonathan Y. Siden, Sara Rodriguez-Diego, Javid Alakbarli, Antonino Di Franco, Jonathan W. Weinsaft
Adjuvant, neoadjuvant, and definitive radiation therapy for malignant pleural mesothelioma
Gwendolyn Cramer, Charles B. Simone II, Theresa M. Busch, Keith A. Cengel

Editorial

Conservatism strikes back: later is better than earlier dialysis for acute kidney injury
Dana Bielopolski, Kamyar Kalantar-Zadeh
Sleep and critical illness: bridging the two pillars at the ATS 2016
Stuti J. Jaiswal, Atul Malhotra, Robert L. Owens
Temperature and duration targets during post-arrest care: choosing the right prescription for the right patient
John C. Greenwood, Abhishek Bhardwaj, Benjamin S. Abella
Examining the paradox of high high-density lipoprotein and elevated cardiovascular risk
Kavisha Singh, Anand Rohatgi
Mortality after red blood cell transfusions from previously pregnant donors: complexities in the interpretation of large data
Susan Kuldanek, Christopher C. Silliman
Optogenetic tools for cell biological applications
Abhirup Mukherjee, Nicole A. Repina, David V. Schaffer, Ravi S. Kane
Editorial on “Transcription factor SPZ1 promotes TWIST-mediated epithelial—mesenchymal transition and oncogenesis in human liver cancer”
Dan J. Raz
Editorial on “Can CT-PET and endoscopic assessment post-neoadjuvant chemoradiotherapy predict residual disease in esophageal cancer”
Chia-Ju Liu, Wei Lu
The hemodynamic impact of acute nasal continuous positive airway pressure treatment in hypertrophic cardiomyopathy: is it safe?
Bo Xu, Reena Mehra
Tumor spread through air space (STAS) is an important predictor of clinical outcome in stage IA lung adenocarcinoma
Hui-Zi Chen, Erin M. Bertino, Kai He
Antiviral prophylaxis of cytomegalovirus reactivation in immune competent patients—the jury remains out
Sara A. Mansfield, Charles H. Cook
Allosterically targeting EGFR drug-resistance gatekeeper mutations
Nicholas Spellmon, Chunying Li, Zhe Yang
Imaging homeostatic sleep pressure and circadian rhythm in the human brain
Zhuo Fang, Hengyi Rao
Tumor mutational burden (TMB) as a biomarker of response to immunotherapy in small cell lung cancer
Yanis Boumber

Letter to the Editor

Response to “VATS vs. thoracotomy regarding postoperative chronic pain”
Emine Ozgur Bayman, Kalpaj R. Parekh, John Keech, Timothy J. Brennan
The role of a decision analysis in treatment of T2N0 esophageal cancer
Tara R. Semenkovich, Bryan F. Meyers, Benjamin D. Kozower, Varun Puri

Case Report

Intraoperative near-infrared imaging can identify subcentimeter colorectal cancer lung metastases during pulmonary metastasectomy
Andrew D. Newton, Jarrod D. Predina, Lydia G. Frenzel-Sulyok, Michael H. Shin, Yiqing Wang, Sunil Singhal
A novel strategy for cardiopulmonary support during lung transplantation
Ramiro Fernandez, Malcolm M. DeCamp, Ankit Bharat

Review Article on Left Ventricular Assist Devices

Left ventricular assist device driveline infections: recent advances and future goals
Anne-Marie Leuck

Short Communication of Interventional Pulmonology Corner

Endobronchial ultrasound—guidance for interstitial photodynamic therapy of locally advanced lung cancer—a new interventional concept
Kassem Harris, Emily Oakley, David Bellnier, Gal Shafirstein

Below are the latest Journal of Thoracic Disease articles published online ahead of print publication.