Vol 18, No 5 (May 31, 2026): Journal of Thoracic Disease

Editorial

Addressing complications after lung resection: evolution from experience, innovation through adversity
Andrei I. Gritsiuta, Roman V. Petrov
Journal of Thoracic Disease  
2026;
18
(5)
:458
.

Original Article

Prediction and intraoperative validation of pulmonary interlobar fissure development based on high-resolution thin-slice computed tomography and multiplanar reconstruction three-dimensional reconstruction technology: a prospective study
Xiuxin Mo, Hongbing Zhang, Chengcheng Chen, Jun Chen
Journal of Thoracic Disease  
2026;
18
(5)
:459
.
Segmentectomy for treating centrally located pulmonary hamartoma: a retrospective analysis of 22 cases
Xiaohui Xu, Yushang Cui
Journal of Thoracic Disease  
2026;
18
(5)
:460
.
Ultrasound-facilitated catheter-directed thrombolysis is associated with improved survival and reduces hospital stay in acute pulmonary embolism: a propensity score-matched analysis
Ahmad G. M. N. Abdelsamad, Rashad Zayat, Yusuf Shieba, Alexander Kersten, Nikolaus Marx, Michael Dreher, Nima Hatam, Sebastian Kalverkamp, Jan Spillner
Journal of Thoracic Disease  
2026;
18
(5)
:461
.
Comparison of pulmonary ventilation/perfusion tomography and conventional diagnostic techniques in the diagnosis of pulmonary thromboembolism
Xue Lv, Fei Du, Jie Fang
Journal of Thoracic Disease  
2026;
18
(5)
:462
.
Intrapleural fibrinolytic therapy for pleural infection: a multicentre real-world comparison of dosing regimens
Glenn Khai Wern Yong, Jonathan Jia Jun Wong, Xiaoe Zhang, Si Ling Young, Brian Lee Wei Chua, Qiao Li Tan, Imran Bin Mohamed Noor, Charlene Jin Yee Liew, Mindy Chu Ming Choong, Wui Mei Chew, Ken Junyang Goh
Journal of Thoracic Disease  
2026;
18
(5)
:463
.
Diagnostic value of lesion-to-spinal cord ratio and apparent diffusion coefficient in differentiating benign and malignant pulmonary nodules and masses
Heng Li, Wei Wei, Chanjuan Yu, Na Zhao, Man Xu, Xumiao Li, Xiao Yang, Xiuzheng Yue, Zhiwei Shen, Yuedong Han
Journal of Thoracic Disease  
2026;
18
(5)
:464
.
Development and internal validation of a CT radiomics-based model for severity classification in HIV-associated Pneumocystis jirovecii pneumonia
Yu Wang, Wei Wang, Caopei Zheng, Yuqing Sun, Budong Chen, Yulin Zhang
Journal of Thoracic Disease  
2026;
18
(5)
:465
.
Parallel-bar versus cross-bar configurations in the Nuss procedure: a systematic review and meta-analysis
Paula Duarte D’Ambrosio, Lucas Monteiro Delgado, Rachid Eduardo Noleto da Nobrega Oliveira, Enzo Campedelli Borges, Mathias de Souza Ribeiro, Giulia Moraes Piazzi, Gustavo Campos Sabino, Patrícia Viana, Rafael Rodrigues Lourencini, Bernardo Mazzini Ketzer, José Ribas Milanez de Campos
Journal of Thoracic Disease  
2026;
18
(5)
:466
.
Efficacy of traditional Chinese exercise on postoperative rehabilitation in lung cancer patients: a systematic review and meta-analysis
Danping Song, Hengyu Liu, Zhe Chen, Jing Du, Ping Lu
Journal of Thoracic Disease  
2026;
18
(5)
:467
.
Robotic mitral valve repair in octogenarians: safety and clinical outcomes compared with younger patients
Takumi Kawase, Kenta Nishiya, Goki Inno, Yukihiro Nishimoto, Kazuki Noda, Ryo Fujii, Kantaro Yanagihara, Yosuke Takahashi
Journal of Thoracic Disease  
2026;
18
(5)
:468
.
The quality and reliability of short videos about chronic obstructive pulmonary disease on TikTok and Bilibili: a cross-sectional study
Yuyu Dai, Xinze Shi, Jun Gu, Tanao Ji
Journal of Thoracic Disease  
2026;
18
(5)
:469
.
Clinical characteristics and risk factors associated with mortality in patients with severe community-acquired pneumonia in the intensive care unit
Kang Zhang, Wenshuai Ji, Hao Yang, Xinyu Miao, Xiaoxuan He, Kai Xie, Haifeng Wang
Journal of Thoracic Disease  
2026;
18
(5)
:470
.
Robustness of tumor control (TCP) and normal tissue complication probabilities (NTCP) for intensity modulated particle radiotherapy in locally advanced lung cancer: a scenario-based uncertainty analysis compared to photon radiotherapy (IMRT)
Xue Ming, Yinxiangzi Sheng, Jian Chen, Kailiang Wu, Xufei Wang, Jingfang Mao, Ningyi Ma
Journal of Thoracic Disease  
2026;
18
(5)
:471
.
Association of systemic inflammation response index with postoperative clinical outcomes among operated patients with aortic dissection: a systematic review with meta-analysis
Zhengqiang Tang, Haina Hao, Fan Tang, Yujia Mao, Miao Chen
Journal of Thoracic Disease  
2026;
18
(5)
:472
.
Concurrent versus sequential intrapleural administration of fibrinolytic and DNase for pleural infections: a systematic review and meta-analysis
Woon Hean Keenan Chong, Ronnie Voon Shiong Tan, Ken Junyang Goh, Wei Jun Dan Ong, Noel Stanley Wey Tut Tay, Dipika Agrawal
Journal of Thoracic Disease  
2026;
18
(5)
:473
.
Sex-specific trends in incidence and mortality of interstitial lung disease and pulmonary sarcoidosis in China compared with global estimates, 1990–2023: an analysis of GBD 2023
Jian Mao, Chunwei Chen, Jingwen Lan, Xiang Yuan
Journal of Thoracic Disease  
2026;
18
(5)
:474
.
Pacemaker implantation after concomitant maze procedure and mitral valve repair in atrial functional mitral regurgitation
Jung Uk Woo, Sungsil Yoon, Woo Sung Jang, Yun Seok Kim, YoHan Bae, Hee Jeong Lee, Jonghoon Yoo, Kyungsub Song
Journal of Thoracic Disease  
2026;
18
(5)
:475
.
Effectiveness and safety of cryoablation therapy for early-stage lung cancer patients: a systematic review and meta-analysis
Kun Zhang, Han Wu, Wentong Zhang, Tianlan Wang, Bo Huang, Lei Cao
Journal of Thoracic Disease  
2026;
18
(5)
:476
.
AHNAK promotes oxidative stress and inflammatory responses in chronic obstructive pulmonary disease by activating the Notch pathway
Chunhui Zhang, Yu Liu
Journal of Thoracic Disease  
2026;
18
(5)
:477
.
The clinical and translational perspectives on the lung microbiome in interstitial lung diseases: a bibliometric review
Mengshi Hang, Yuchen Liu, Xiao Shen, Yuhui Zhao, Yongdong Xu, Xinyi Gong, Linlin Xu, Na Li, Lei Dong
Journal of Thoracic Disease  
2026;
18
(5)
:478
.
Clinical factors associated with the development of Staphylococcus aureus pneumonia in patients with airway colonization
Reimi Mizushima, Yuta Kono, Haruka Motohashi, Mariko Kogami, Mayuko Ishiwari, Ryota Kikuchi, Kenichi Kobayashi, Shinji Abe
Journal of Thoracic Disease  
2026;
18
(5)
:479
.
Age-related differences in pleural adhesion and perioperative outcomes in uniportal video-assisted thoracoscopic surgery segmentectomy
Seha Ahn, Youngkyu Moon
Journal of Thoracic Disease  
2026;
18
(5)
:480
.
Pulmonary artery involvement contributes to the recurrence of hemoptysis after bronchial artery embolization in patients with chronic pulmonary aspergillosis
Yingjie Chen, Min Liu, Wei Yu, Jinnan Zhong, Shi Chen, Ting Zhang, Wei Qin, Ziyang Zhu, Chenghong Li, Fajiu Li
Journal of Thoracic Disease  
2026;
18
(5)
:481
.
An interpretable early intensive care unit model for predicting in-hospital mortality in trauma patients combined with rib fractures: development and external validation
Liwen Hu, Penglong Zhao, Longxiao Cai, Kai Dong, Yumeng Du, Xinyue Yao, Yi Shen
Journal of Thoracic Disease  
2026;
18
(5)
:482
.
Outcomes of comorbid mental health disorders in cardiovascular surgery
Grace M. Soltesz, Jose L. Diz Ferre, Guangjin Zhou, Siran M. Koroukian, Krish C. Dewan
Journal of Thoracic Disease  
2026;
18
(5)
:483
.
Standardization of Chinese speech tasks for heart failure voice analysis: a cross-sectional diagnostic classification study
Hanyue Zhang, Changxin Li, Hangyu Li, Rong Sheng, Si Sun, Qian Chen, Yunfei Meng, Yifan Yao, Liwei Liu, Ming Chu
Journal of Thoracic Disease  
2026;
18
(5)
:484
.
Computed tomography features associated with pneumothorax susceptibility in pectus excavatum: a retrospective case-control study of lobar morphometry, attenuation metrics, and machine-learning projection
In Sub Kim, Jae Jun Kim, Kyong Shil Im, Yoon Ho Kim, Jeong Hwan Ryu
Journal of Thoracic Disease  
2026;
18
(5)
:485
.
A 20-year bibliometric analysis on the development trends and hotspots of pectus excavatum research: 2005–2025
Zichen Zhang, Fangfang Zhang, Lijuan Zhang, Shaoshi Lin, Bangzhen Ma, Mengdi Li, Mingyu Cui, Gang Wang
Journal of Thoracic Disease  
2026;
18
(5)
:486
.
Tumor stage, squamous histology and male sex predict positive resection margins in non-small cell lung cancer patients undergoing anatomical resection—a retrospective study from a high-volume thoracic surgery unit
Mircea Gabriel Stoleriu, Konrad Steinestel, Matteo Grimmer, Lena-Maria Löwer-Kiem, Moritz Witzenhausen, Jan Sölter, Sebastian Brill, Annette Arndt
Journal of Thoracic Disease  
2026;
18
(5)
:487
.
Bibliometric and visualization analysis of non-intubated thoracic anaesthesia [2014–2025]
Yu Che, Lei Chen, Shenghua Yi, Mochi Guo, Jiaqi Liu, Yulong Wang
Journal of Thoracic Disease  
2026;
18
(5)
:488
.
Analysis of survival and prognostic differences in locally advanced or metastatic non-squamous non-small cell lung cancer with KRAS mutations
Xiangyu Du, Shanxin Zhang, Yahui Lv, Zhefeng Liu
Journal of Thoracic Disease  
2026;
18
(5)
:489
.
Mitral valve surgery combined with on-pump coronary artery bypass grafting (CABG) versus off-pump or on-pump beating heart CABG: a retrospective cohort study
Huixiang Su, Yinfan Zhu, Haiyang Hu, Xiaohan Zhong, Lu Dai, Qianxian Li, Hongjia Zhang, Haiyang Li, Yuyong Liu, Dongjie Li, Wenjian Jiang
Journal of Thoracic Disease  
2026;
18
(5)
:490
.
Application of mild hypothermic arch-clamping technique in the repair of DeBakey type I aortic dissection
Cheng Luo, Xiongwei Cai, Chen Fang, Yugui Li, Jun Peng, Wei Lu, Baoshi Zheng
Journal of Thoracic Disease  
2026;
18
(5)
:491
.
Expression of YTHDF1 and YTHDF2 in lung squamous cell carcinoma and their correlation with PD-L1
Liting Cai, Honglan Qu, Kai Feng, Huizhen He, Fengyun Wang
Journal of Thoracic Disease  
2026;
18
(5)
:492
.
Lung cancer education on social media: use patterns and content preferences from a cross-sectional study
Eric K. Singhi, Susana Fortich, Victoria Yin, Mara B. Antonoff
Journal of Thoracic Disease  
2026;
18
(5)
:493
.
Sex modifies the association between blood pressure variability and lung function decline among population over 45 years old: a pooled analysis of two national cohorts
Jing Fu, Longfei Xie, Jing Zhao, Rui Zhao
Journal of Thoracic Disease  
2026;
18
(5)
:494
.
Long-term outcomes of virtual-assisted lung mapping compared with CT-guided percutaneous marking
Masahiro Yanagiya, Chika Harada, Shuri Aoki, Masaaki Sato
Journal of Thoracic Disease  
2026;
18
(5)
:495
.
Long-term outcomes of lung transplantation in the elderly: an analysis using the UNOS database
Osnat Shtraichman, J. Sam Meyer, Arielle Zur, Gil Leor, Dan Aravot, Yury Peysakhovich, Yael Shostak, Mordechai R. Kramer, Yaron D. Barac
Journal of Thoracic Disease  
2026;
18
(5)
:496
.
Global trends and research hotspots in enhanced recovery after surgery (ERAS) for lung cancer resection: a bibliometric and visual analysis (2010–2025)
Chunxiu Dong, Haiping Yu
Journal of Thoracic Disease  
2026;
18
(5)
:497
.
Clinical features and prognostic factor of small (≤2 cm) lung cancer associated with cystic airspaces
Yuichiro Machida, Kento Suzuki, Takashi Kojima, Takumi Sonokawa, Norihito Kawasaki, Jitsuo Usuda
Journal of Thoracic Disease  
2026;
18
(5)
:498
.
Clinical phenotypes of secondary spontaneous pneumothorax (SSP) in different underlying lung diseases: a retrospective study and literature review on the clinical heterogeneity in this single entity
Hei-Shun Cheng, Charles Wong, Pui-Hing Chiu, Vinson Nelson Yew, Chi-Chung Jeffrey Wong, Chun-Wai Tong, Pui-Ling Flora Miu
Journal of Thoracic Disease  
2026;
18
(5)
:499
.
Esophageal cancer recurrence after multimodality therapy: analysis of patterns and implications on long-term survival
Farah A. Abdallah, Belisario A. Ortiz, Robert A. Vierkant, Carlos A. Puig, K. Robert Shen, Dennis A. Wigle, Stephen D. Cassivi, Janani S. Reisenauer, Krishan R. Jethwa, Cameron M. Callaghan, Zhaohui Jin, Harry H. Yoon, Christopher L. Hallemeier, Luis F. Tapias
Journal of Thoracic Disease  
2026;
18
(5)
:500
.
Cardiovascular and cerebrovascular related death among patients with esophageal cancer: an international multicenter study
Jiangshan Ai, Lianzheng Zhao, Yang Li, Guodong Shi, Zhen Zhang, Xiaofei Li, Yuanyong Wang
Journal of Thoracic Disease  
2026;
18
(5)
:501
.
Construction and validation of a prognostic model for in-hospital multiple organ dysfunction syndrome in ICU patients with respiratory failure based on ultrasound and laboratory parameters
Qian Wang, Qun Wu, Fengying Jie, Wen Sun, Fengtao Wang, Shuping Deng, Jiao Han, Fang Dong
Journal of Thoracic Disease  
2026;
18
(5)
:502
.
Development and validation of a diagnostic model for malignant pleural effusion based on random forest
Xu Guo, Xiao-Lei Wei, Shu-Min Yin, Yu-Peng Li, Kan Zhai, Huan-Zhong Shi, Zheng Wang
Journal of Thoracic Disease  
2026;
18
(5)
:503
.
m6A target gene signatures reveal immune-related diagnostic biomarkers in systemic sclerosis-associated pulmonary arterial hypertension
Yansheng Jin, Wen Xu, Maoxiao Fan, Xiaozhong Li
Journal of Thoracic Disease  
2026;
18
(5)
:504
.
Head-to-head comparison of maximum standardized uptake value and three-dimensional consolidation-to-tumor ratio for preoperative prediction of International Association for the Study of Lung Cancer grade 3 in clinical stage IA invasive lung adenocarcinoma
Satoshi Fumimoto, Kiyoshi Sato, Takahiro Katsumata, Nobuharu Hanaoka
Journal of Thoracic Disease  
2026;
18
(5)
:505
.
Video double-lumen endotracheal tube reduces hypoxemia during one-lung ventilation in thoracoscopic surgery: a prospective randomized controlled trial
Si Long, Yuhang Li, Xiaoyang Zheng, Fang Ye, Jiayan Li, Yu Yu, Juanying Guo, Wenqi Huang, Zhongxing Wang, Rong Hu
Journal of Thoracic Disease  
2026;
18
(5)
:506
.
FDG-PET/CT data enhances machine learning prediction of occult lymph-node metastasis in lung adenocarcinoma
Akihiro Sasaki, Haruhiko Shiiya, Hideki Ujiie, Kenji Hirata, Takahiro Ogawa, Sho Narita, Shinya Otsuka, Hiroshi Yamasaki, Kazuto Ohtaka, Aki Fujiwara-Kuroda, Masato Aragaki, Tatsuya Kato
Journal of Thoracic Disease  
2026;
18
(5)
:507
.
Minimally invasive off-pump coronary artery bypass grafting is associated with reduced postoperative intra-aortic balloon pump use
Yanbin Lei, Guang Li, Jiazhen Mei, Yi Xu, Zhao Yang, Zheng Qu, Yuming Hao, Bin You
Journal of Thoracic Disease  
2026;
18
(5)
:508
.
Association of triglyceride-glucose index and triglyceride-glucose body mass index with risk and prognosis of chronic obstructive pulmonary disease: a systematic review and meta-analysis
Yan Wu, Nianhong Wu, Langli Gao
Journal of Thoracic Disease  
2026;
18
(5)
:509
.
Post-LVAD cognitive trajectories and determinants of non-improvement in end-stage heart failure
Mingxiu Wen, Shuanglei Zhao, Yi Hu, Qianxian Li, Siji Chen, Hongjia Zhang, Ming Gong
Journal of Thoracic Disease  
2026;
18
(5)
:510
.
Clinical characteristics, symptom burden, and pulmonary function trajectories of spirometry- and MMEF-defined bronchodilator responsiveness in COPD: a single-center prospective study
Zhaoqian Gong, Junrao Wang, Meijia Chen, Xueying Zhao, Junwen Huang, Ying Chen, Yuling Hu, Hailun Huang, Wenqu Zhao, Jianpeng Liang, Haijin Zhao
Journal of Thoracic Disease  
2026;
18
(5)
:511
.
Clinical impact and prognostic factors of early radiotherapy in limited-disease small-cell lung cancer cohort
Kyung-Il Han, Hyun Seok Kwak, Yechan Song, Min Jee Kim, Wonjun Ji, Jae Cheol Lee, Chang Min Choi
Journal of Thoracic Disease  
2026;
18
(5)
:512
.
A prognostic nomogram for oligometastatic non-small cell lung cancer incorporating extent of primary tumor resection as a key predictor
Zixuan Fei, Yang Pan, Xuanhong Jin, Leilei Wu, Junnan Ru, Yan Zhang, Yuqi Lin, Jian Zeng, Feng Li
Journal of Thoracic Disease  
2026;
18
(5)
:513
.
Development and internal validation of a prognostic model for esophageal cancer liver metastases using the Surveillance, Epidemiology, and End Results database
Jingyuan Jiang, Yukai Zeng, Jun Wan, Lening Zhang, Zhe Zhang, Rong Bai, Chao Wang, Fengwu Lin
Journal of Thoracic Disease  
2026;
18
(5)
:514
.
Machine learning to predict distant metastasis risk and prognostic analysis in T1–2 esophageal cancer: a study based on the SEER database
Pubo Shi, Pengjie Yang, Haibo Wu, Changhong Lian, Benben Zhu, Yong Li
Journal of Thoracic Disease  
2026;
18
(5)
:515
.
Pressurized intrathoracic aerosol chemotherapy (PITAC) for malignant pleural mesothelioma—ex vivo evaluation of optimal treatment conditions and comparison with hyperthermic intrathoracic chemotherapy (HITOC)
Katharina Flöthmann, Norman Zinne, Peter Braubach, Alina Meininger, Imke Becker, Nicole Ernst, Arjang Ruhparwar, Hayan Merhej, Patrick Zardo
Journal of Thoracic Disease  
2026;
18
(5)
:516
.
Assessment of CT quantitative characteristics derived from CT in connective tissue disease-associated interstitial lung disease
Yuxin Cheng, Rongrong Fan, Yueze Li, Jiaming Zheng, Li Fan, Shiyuan Liu, Yu Guan, Yi Xiao
Journal of Thoracic Disease  
2026;
18
(5)
:517
.
Perioperative fatigue after lung resection for pulmonary nodules and early-stage lung cancer: a systematic review and meta-analysis
Shangqing Xu, Yan Sun, Kexin Ma, Xiaoyan Han, Yu Gu, Hongying Jin, Xiaoli Ma, Diego Gonzalez-Rivas, Minjie Ma
Journal of Thoracic Disease  
2026;
18
(5)
:518
.
Association between blood urea nitrogen-to-creatinine ratio trajectories and mortality in patients with severe pneumonia requiring invasive mechanical ventilation: a Medical Information Mart for Intensive Care IV (MIMIC-IV) database analysis
Shaopeng Zheng, Jiajia Chen, Zekai Huang, Zixun Huang, Qiangzhou Xu, Limin Ma
Journal of Thoracic Disease  
2026;
18
(5)
:519
.
The impact of Marfan syndrome on long-term outcomes in acute type A aortic dissection after extensive arch surgery
Kai Zhang, Chenyu Zhou, Yumeng Ji, Shiqi Gao, Xiaonan Li, Yutao Li, Cuntao Yu, Juntao Qiu, Honglei Zhao
Journal of Thoracic Disease  
2026;
18
(5)
:520
.
Impact of surgical margins on treatment outcomes in pulmonary resections for Aspergillus-related fungal infections: an initial analysis
José de Sá Moraes Neto, Jaqueline Schaparini Fonini, Ellen Caroline Toledo do Nascimento, Paulo Manuel Pêgo-Fernandes, Alessandro Wasum Mariani
Journal of Thoracic Disease  
2026;
18
(5)
:521
.
Predicting pulmonary nodule growth from a single time point: a fusion model of radiomics and deep learning to optimize follow-up strategies
Zhimin Xu, Xiang Wang, Zirui Cao, Xianpan Pan, Jiayi Zhang, Fukai Li, Lei Chen, Yi Xiao, Shiyuan Liu
Journal of Thoracic Disease  
2026;
18
(5)
:522
.
Monitoring pneumonia onset and severe respiratory infectious diseases using quantitative computed tomography, validation amidst the coronavirus disease 2019 outbreak at the end of 2022 in the Chinese mainland
Ting Cheng, Tiantian Zhang, Jingci Xu, Yong Li, Yaqing Jin, Shengyu Wang, Li Luo
Journal of Thoracic Disease  
2026;
18
(5)
:523
.
A single-arm, single-center phase II clinical study of concurrent brain radiotherapy combined with tislelizumab and chemotherapy in patients with small-cell lung cancer and brain metastases
Shuhao Que, Enhui Dai, Jingjing Wang, Qi Mo, Huan Xu, Yiqin Qiu, Xu Liang, Shuwei Zhai, Yuetong Li, Guoqiang Zhong, Wei Feng, Chao Chen
Journal of Thoracic Disease  
2026;
18
(5)
:524
.
Effect of dezocine on the median effective dose of sufentanil for blunting hemodynamic responses to endotracheal intubation during anesthesia induction
Weiwei Ye, Jiansong Yu, Wei Chen, Xiaodan Wang, Donghang Cao, Nanjin Chen
Journal of Thoracic Disease  
2026;
18
(5)
:525
.
Development and validation of a collagen score-based prediction model for neoadjuvant chemoimmunotherapy efficacy in locally advanced esophageal squamous cell carcinoma
Xiao-Feng Chen, Huai-Yuan Zhang, Wei-Jie Chen, Jun-Peng Lin, Hang Zhou, Yu-Jie Chen, Peng-Qiang Gao, Feng Wang
Journal of Thoracic Disease  
2026;
18
(5)
:526
.
Development and internal validation of dynamic nomograms for predicting recurrence and survival in patients with resected combined small cell lung cancer
Chunhua Zeng, Jingjuan Zhu, Jingming Xue, Jinlong Teng, Hong Liu, Baohui Han, Jing Wang, Yanan Wang
Journal of Thoracic Disease  
2026;
18
(5)
:527
.
Surgery versus radiotherapy after neoadjuvant immunochemotherapy in limited-stage small cell lung cancer
Rui Zou, Ziyue Zhu, Xiao Teng, Sizhe Yu, Xiayi Lyu
Journal of Thoracic Disease  
2026;
18
(5)
:528
.
Elevated serum Cyfra 21-1 levels predict poor prognosis in thymic tumors: a retrospective single-center study
Xuefei Zhang, Ning Xu, Zhitao Gu, Wentao Fang
Journal of Thoracic Disease  
2026;
18
(5)
:529
.
Downregulation of EZR inhibits esophageal squamous cell carcinoma progression through the impairment of focal adhesion activation and the EGFR-mediated PI3K/AKT pathway
Zhen-Yu Hu, Wei-Hao Deng, Jun-Xiu Huang, Zhe Li, Yu-Zhen Zheng, Hong-Ying Liao
Journal of Thoracic Disease  
2026;
18
(5)
:530
.
Research trends and hot topics of radiation-induced pulmonary fibrosis: a bibliometric analysis and visualization study from 2015 to 2025
Yuxin Zhong, Yiren Wang, Li Zhang, Hao Wang, Kaili Dai
Journal of Thoracic Disease  
2026;
18
(5)
:531
.

Brief Report

Clinical benefits of covering the bronchial stump with a free pericardial fat pad after thoracoscopic lobectomy
Sota Yoshimine, Toshiki Tanaka, Junichi Murakami, Hiroshi Kurazumi, Kimikazu Hamano
Journal of Thoracic Disease  
2026;
18
(5)
:532
.

Study Protocol

Rehabilitative intervention of frailty for patients with chronic respiratory disease (REINFORCE study): research protocol for a multicentre, randomised controlled trial
Tadayoshi Nonoyama, Masatoshi Hanada, Osamu Nishiyama, Shinichi Arizono, Kensuke Kataoka, Atsuhito Nakazawa, Yorihide Yanagita, Tatsuya Morishita, Akira Morino, Atsuyoshi Kawagoshi, Takeshi Inagaki, Takatsugu Kubo, Masashi Shiraishi, Shinjiro Miyazaki, Shuntaro Sato, Ryo Kozu
Journal of Thoracic Disease  
2026;
18
(5)
:533
.
Efficacy and safety of Xingqin Ganke Granules in postinfectious cough: study protocol for a multicenter, randomized, double-blind, placebo-controlled, dose-ranging phase II clinical trial
Qing Shen, Xuan Chen, Guihua Xu, Shiqi Sun, Yan Xue, Linqiong Zhou, Fengjun Zhang, Wei Zhang
Journal of Thoracic Disease  
2026;
18
(5)
:534
.

Review Article

Immune research progress of Slit2-Robo signaling axis in chronic obstructive pulmonary disease: a narrative review
Weiwei An, Dejin Liang
Journal of Thoracic Disease  
2026;
18
(5)
:535
.
Perioperative management of cardiac implantable electronic devices: a state of the art narrative review
Rohesh J. Fernando, Ettore Crimi, Karuna Puttur Rajkumar, Bryan E. Marchant, Chandrika R. Garner, Steven C. Eastlack, Megan H. Hicks, Roger L. Royster
Journal of Thoracic Disease  
2026;
18
(5)
:536
.
Artificial intelligence-assisted early screening of lung cancer and accurate diagnosis of pulmonary nodules: research progress and clinical prospects from radiomics to multi-omics integration: a narrative review
Junwei Wang, Guixue Yang, Zhuoxin Dai, Miao Yang, Peng Dai, Mengyang Chang, Quan-Xing Liu, Ji-Gang Dai
Journal of Thoracic Disease  
2026;
18
(5)
:537
.
Biologic switching in allergic bronchopulmonary aspergillosis: a scoping review of published clinical experience
Qiurong Hu, Xuanyu Pan, Ruchong Chen, Ganlu Li, Yixuan Li, Yu Zheng, Ziyang Zhong, Xinyi Zhang, Yuhang Chen, Jiazhen Ye, Jielin Duan, Jing Li
Journal of Thoracic Disease  
2026;
18
(5)
:538
.
Risk factors, pathogenesis, and botanical drugs interventions for postoperative pulmonary complications after cardiothoracic surgery: a narrative review
Haoran Wang, Zhongyi Liang
Journal of Thoracic Disease  
2026;
18
(5)
:539
.
Neural mechanisms of cough: insights from multimodal magnetic resonance imaging—a narrative review
Xinyi Liu, Yijing Wang, Chen Chen, Chunwei Wu, Bo Zhang, Zhandong Liu, Ying Xie, Peijun Gui
Journal of Thoracic Disease  
2026;
18
(5)
:540
.
Narrative review: clinical application and challenges of circulating tumor DNA in treatment response evaluation and prognostic prediction for esophageal cancer
Rentong Gu, Tao Liu, Hai Jin, Xiaowei Wang
Journal of Thoracic Disease  
2026;
18
(5)
:541
.
2025 annual review of basic and translational research advances in pulmonary fibrosis: a narrative review
Juan Li, Xiao Xiao Tang
Journal of Thoracic Disease  
2026;
18
(5)
:542
.
Thoracic electrical impedance tomography from technological promise to clinical reality: the Chinese experience
Zhanqi Zhao
Journal of Thoracic Disease  
2026;
18
(5)
:543
.
Research progress on immune microenvironment and biomarkers of small cell lung cancer
Na Di, Heping Sun, Qi Wang, Rui Zhong, Lin Tian, Peiyan Zhao, Hui Li, Haifeng Liu
Journal of Thoracic Disease  
2026;
18
(5)
:544
.
Systemic hypothermia in non-aortic cardiac surgery: a narrative review
Daniel Kyrillos Ragheb, Nika Samadzadeh Tabrizi, Anthony L. Zaki, Alexander D. Shapeton
Journal of Thoracic Disease  
2026;
18
(5)
:545
.
A systematic review of artificial intelligence-based diagnosis models for idiopathic pulmonary fibrosis
Ruo-Nan Yan, Hai-Yang Hu, Zi-Ru Ma, Wen-Han Zhao, Li-Li Xu, Dan-Yang Zang, Shu-Guang Yang, Xue-Qing Yu
Journal of Thoracic Disease  
2026;
18
(5)
:546
.
Progress on the mechanism of Piezo1 in mechanical ventilation-induced lung injury
Yulong Jia, Han Xue, Chenxu Chou, Xiaoyu Zhang, Bo Chen, Xiaguang Duan
Journal of Thoracic Disease  
2026;
18
(5)
:547
.
Clinical application of liquid biopsy in the diagnosis and treatment of lung cancer: taking ctDNA for example—a narrative review
Ziqiang Jiang, Hongxue Cui
Journal of Thoracic Disease  
2026;
18
(5)
:548
.
Artificial intelligence in thoracic surgery: a narrative review of clinical advances and applications in 2025
Yudong Zhang, Zheng Yang, Yiluo Lin, Yulin Zhao, Youtao Zhou, Chenyuan Deng, Keyao Dai, Hengrui Liang, Yueming Su
Journal of Thoracic Disease  
2026;
18
(5)
:549
.
Advances in surgical treatment for valvular heart disease: a narrative review of 2025 studies
Jiaqi Wu, Ming Chen, Chen Jiang, Xingyu Qian, Keqing Yu, Yidan Zheng, Pengning Fan, Yuqi Liu, Jiu Pu, Lin Fan, Zhe Chen, Haoyang Zhai, Zhengfeng Fan, Jian Sun, Teng Zeng, Zihao Zhou, Li Xu, Fei Li
Journal of Thoracic Disease  
2026;
18
(5)
:550
.
Sex hormone-binding globulin and coronary heart disease: a narrative review of associations and biomarker potential
Xu Liu, Meng Chen, Wen Dai, Haizhu Gao, Xueying Chen, Ronghua Gao
Journal of Thoracic Disease  
2026;
18
(5)
:551
.
Clinical research on pulmonary hypertension from a 2025 perspective: a narrative review
Qianwen Bai, Haoyu Liu, Hongquan Wang, Yao Yao, Jia Deng, Tao Wang
Journal of Thoracic Disease  
2026;
18
(5)
:552
.

Editorial Commentary

Durability of Nitinol in self-expanding devices
Francesco Nappi, Cristiano Spadaccio
Journal of Thoracic Disease  
2026;
18
(5)
:553
.
Serratus anterior plane blocks for median sternotomy anesthesia: back to the drawing board
Rohesh J. Fernando, Salvador E. Pena, Tomasz Dobrzanski, David Watts
Journal of Thoracic Disease  
2026;
18
(5)
:554
.
Toward multi-domain lung cancer research databases: opportunities and challenges from MCC-MELD
Yuki Joyama, Stephanie Tuminello, Emanuela Taioli
Journal of Thoracic Disease  
2026;
18
(5)
:555
.
STORM-PE: early right ventricular unloading in intermediate-high risk pulmonary embolism
Hassan Saleh, Firas Amil, Luke Domaleski
Journal of Thoracic Disease  
2026;
18
(5)
:556
.
Biomarker-driven maintenance therapy in extensive-stage-small cell lung cancer: evaluating the SWOG S1929 clinical trial
Tiffany Johnston, Daniel Breadner, Jacques Raphael
Journal of Thoracic Disease  
2026;
18
(5)
:557
.
Combined organ resection for esophageal cancer invading adjacent organs is becoming a safe and curative procedure
Masanobu Nakajima, Kazuyuki Kojima
Journal of Thoracic Disease  
2026;
18
(5)
:558
.
Are lazertinib and osimertinib comparable for treating advanced EGFR-mutant non-small cell lung cancer?—insights and limitations from the MARIPOSA study
Edyta Maria Urbanska, Eric Santoni-Rugiu, Morten Grauslund, Jens Benn Sørensen
Journal of Thoracic Disease  
2026;
18
(5)
:559
.
From contraindication to consideration: the role of esophagectomy in stage IV esophageal adenocarcinoma
Agustina A. Pontecorvo, Enrique F. Elli
Journal of Thoracic Disease  
2026;
18
(5)
:560
.
The NAVIGATE trial: early identification and management of mild acute hypoxemic failure, does timing matter outside ICUs?
Jean-Pierre Frat, Rémi Coudroy, Arnaud W. Thille
Journal of Thoracic Disease  
2026;
18
(5)
:561
.
The COCOON trial: wrapping potent EGFR therapy in proactive supportive care
Kushal Kriplani, Won Jin Jeon, Jeremy Cetnar, Chetan Vakkalagadda, Rajat Thawani
Journal of Thoracic Disease  
2026;
18
(5)
:562
.
The technical evolution and persistent challenges in the surgical management of mitral annular calcification
Shinji Kanemitsu
Journal of Thoracic Disease  
2026;
18
(5)
:563
.
Preserve or ligate?—navigating perfusion-safe oncologic precision in gastroesophageal junction cancer surgery
Evelyn Alexander, Stephanie G. Worrell
Journal of Thoracic Disease  
2026;
18
(5)
:564
.
Mitral annular calcification in high-risk patients: to operate or not to operate
Ryaan EL-Andari, Maira Machhiwala, Sabin J. Bozso
Journal of Thoracic Disease  
2026;
18
(5)
:565
.
Enabling precision therapy through dermatologic prophylaxis: lessons from COCOON
Saqib Raza Khan, Michela Febbraro, Jacques Raphael, Daniel Breadner
Journal of Thoracic Disease  
2026;
18
(5)
:566
.
Rethinking flow: the paradox of renoprotection without increased renal blood flow in cardiopulmonary bypass
Shiksha Mohan, Ronald A. Shaju, Sharan Misra, Titiksha Sharma, Veeraj K. Sirivolu, Abhinav Rajkumar, Anthony Rodas-Camacho, Aizah Zaidi, Dhruv Dhingra, Ilma Khan, Rishav Bhattacharya, Vishal Pancholy, Shivam Banerjee, Shreyo Ghosh, Shiyi Li, Kenneth K. Liao, Carl P. Walther, Nandan K. Mondal
Journal of Thoracic Disease  
2026;
18
(5)
:567
.
SLFN11 expression as a marker of small cell lung cancer vulnerability to combined PARP inhibitors and immune checkpoint inhibitors during maintenance
Jean-Louis Pujol
Journal of Thoracic Disease  
2026;
18
(5)
:568
.

Letter to the Editor

Clarifying the role of flumonertinib rechallenge in EGFR-mutated non-small cell lung cancer
Haoyu Wang, Chenyue Zhang, Shanshan Du, Haiyong Wang
Journal of Thoracic Disease  
2026;
18
(5)
:569
.
Intercostal nerve blocks should set the standard for regional analgesia in video-assisted thoracic surgery
Steve Coppens
Journal of Thoracic Disease  
2026;
18
(5)
:570
.
Chikungunya fever in Guangdong, China, 2025: rapid spread and challenges
Zhijie Lin, Ruibin Liu, Xuanfeng Li, Zhiqi Zeng, Xiaoyan Deng, Zifeng Yang, Yihui Huang, Di Wang, Chitin Hon
Journal of Thoracic Disease  
2026;
18
(5)
:571
.
Selection bias and molecular blind spots: re-evaluating flumonertinib rechallenge in third-generation TKI-resistant non-small cell lung cancer
Mengnan Li, Yani Xu, Kaili Dai, Lianqin Tao, Junfei Zhu
Journal of Thoracic Disease  
2026;
18
(5)
:572
.
Selective coronary venous bypass grafting for diffuse right coronary artery disease: early safety, uncertain durability
Sebastian Veliz Padilla
Journal of Thoracic Disease  
2026;
18
(5)
:573
.
Clinical implementation of amino acids infusion for perioperative renal protection
Stefano Fresilli, Rosario Losiggio, Giovanni Landoni
Journal of Thoracic Disease  
2026;
18
(5)
:574
.