Vol 18, No 6 (June 30, 2026): Journal of Thoracic Disease

Original Article

A predictive model for immunotherapy in extensive-stage small cell lung cancer based on peripheral blood
Jiacheng Wang, Heng Li, Lanjun Li, Zhiqing Liu, Hanting Zhao, Xiao Ma, Shaobin Qiu, Tianshun Wang, Gaofeng Li
Journal of Thoracic Disease  
2026;
18
(6)
:576
.
 (30 June 2026) 
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Association between preoperative nutritional status and mortality in patients with type B aortic dissection undergoing thoracic endovascular aortic repair: a retrospective cohort study
Jiahe Zhang, Shuangshuang Li, Wen Li, Lingxu Kong, Zhichen Ding, Kaiwen Zhao, Jian Zhou
Journal of Thoracic Disease  
2026;
18
(6)
:577
.
 (30 June 2026) 
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Silencing of BCAT1 induces ferroptosis and inhibits brain metastasis of non-small cell lung cancer via activating the cGAS-STING pathway
Fan Yang, Yuying Li, Huijiao Zhou, Xin Bi, Dongjie Wang
Journal of Thoracic Disease  
2026;
18
(6)
:578
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 (30 June 2026) 
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Visualization of the thoracic sympathetic chain in MLS embalmed body donors: a feasibility study and surgical perspective
Dennis Aliev, Hanno Steinke, Thomas Schröter, Laura V. Klotz, Fabrizio Minervini, Isabella Metelmann, Charlotte Kulow, Matthias Steinert, Sebastian Krämer
Journal of Thoracic Disease  
2026;
18
(6)
:579
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 (30 June 2026) 
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Ultra-low versus low tidal volume ventilation in acute respiratory distress syndrome: a systematic review and meta-analysis
Ya Wang, Nickjaree Songsangvorn, Jianchun Li, Xiaoli Chen, Jinquan Xie, Yu Pi, Xinxin Yang, Quanzhen Liu, Xiaoqing Liu, Haibo Zhang, Yonghao Xu
Journal of Thoracic Disease  
2026;
18
(6)
:580
.
 (30 June 2026) 
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Preservation of the right bronchial artery by maintaining the azygos arch during minimally invasive esophagectomy: a two-center retrospective cohort study
Yasuo Tsuda, Tomonori Nakanoko, Yasue Kimura, Keita Natsugoe, Qingjiang Hu, Tetsuro Kawazoe, Sho Nambara, Koji Ando, Mizuki Ninomiya, Eiji Oki, Tomoharu Yoshizumi
Journal of Thoracic Disease  
2026;
18
(6)
:581
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 (30 June 2026) 
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Comprehensive analysis of POLD2 as a potential biomarker for modulating the immune microenvironment and predicting immunotherapy response in lung adenocarcinoma
Wu Zhu, Hong Zhang, Zhiqin Guo, Lin Zhang, Shaoqing Hu, Wanxin Wu, Xiangyi Chen, Leiyan Wei
Journal of Thoracic Disease  
2026;
18
(6)
:582
.
 (30 June 2026) 
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An association between epicardial adipose tissue and prognosis in acute myocardial infarction: a systematic review and meta-analysis
Jing Wang, Nengzong Deng, Yuan Huang, Ziming Liu, Hong Zeng
Journal of Thoracic Disease  
2026;
18
(6)
:583
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 (30 June 2026) 
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Comparison of learning curves between electromagnetic navigation bronchoscopy and Ion robotic bronchoscopy for preoperative localization
Hongjiang Liu, Hecheng Zhang, Xiang Tang, Yong Ge, Xingyu Zhu, Teng Sun, Cheng Zhang, Hao Zhang, Shoujie Feng
Journal of Thoracic Disease  
2026;
18
(6)
:584
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 (30 June 2026) 
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Machine learning-based preoperative prediction of spread through air spaces in clinical stage IA non-small cell lung cancer: a single-center study integrating clinical and CT imaging characteristics
Xuanyu Zhu, Jinhao Kou, Heng Tao, Xiaolong Liu, Zhihui Yang, Jing Luo, Ciren Yundan, Yi Shen
Journal of Thoracic Disease  
2026;
18
(6)
:585
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 (30 June 2026) 
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Chemoimmunotherapy improves surgical resection rate and survival versus chemotherapy in potentially resectable non-small cell lung cancer: a real-world propensity score-matched study
Wei Wang, Aiqin Gao, Yihui Ge, Yuanyuan Jiang, Zijie Wu, Yiling Gan, Hua Zhang, Yuping Sun
Journal of Thoracic Disease  
2026;
18
(6)
:586
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 (30 June 2026) 
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Adverse events after transcatheter edge-to-edge repair: descriptive post-marketing surveillance analysis of MitraClip and PASCALTM from the Manufacturer and User Facility Device Experience (MAUDE) registry
Ananya Kommuri, Adwoa Boatemaah Adu-Sarkodee, Sheriff N. Dodoo
Journal of Thoracic Disease  
2026;
18
(6)
:587
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 (30 June 2026) 
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Impact of prior malignancy on non-small cell lung cancer presentation, management, and survival
Gabriella R. Rasmussen, Eric Klipsch, Rupak Mukherjee, Zachary Matthews, Ian C. Bostock, Kathryn E. Engelhardt
Journal of Thoracic Disease  
2026;
18
(6)
:588
.
 (30 June 2026) 
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Prognostic role of hemoglobin, albumin, lymphocyte and platelet score in esophageal cancer: a systematic review and meta-analysis
Huanhuan Yang, Yonghong Luo, Yang Hu
Journal of Thoracic Disease  
2026;
18
(6)
:589
.
 (30 June 2026) 
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GNL3L-LMNB1 signaling axis promotes lung squamous cell carcinoma growth and ferroptosis resistance via NF-κB activation
Hong Hu, Yue Wang, Hang Li, Haiqing Chen, Longlong Shao, Xusheng Ding, Yuan Li, Jie Wang
Journal of Thoracic Disease  
2026;
18
(6)
:590
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 (30 June 2026) 
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Assessment of cardiac and pulmonary pressure for transatrial-to-left-ventricular cannulation: implications for surgical safety
Atsutaka Aratame, Masanori Sakaguchi, Toshio Baba, Yosuke Takahashi
Journal of Thoracic Disease  
2026;
18
(6)
:591
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 (30 June 2026) 
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A retrospective study comparing T3 ganglionectomy and R4 sympathicotomy for reducing compensatory hyperhidrosis in primary palmar hyperhidrosis
Ji Hoon Kim, Duk Hwan Moon, Sungsoo Lee, Beatrice Chia-Hui Shih
Journal of Thoracic Disease  
2026;
18
(6)
:592
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 (30 June 2026) 
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Association of lung perfusion single-photon emission computed tomography (SPECT) with postoperative lung function decline after segmentectomy
Lucas Wilhelm, Saifeddine Melki, Laetitia Imbert, Achraf Bahloul, Ulrick Gerhard, Timothée Zaragori, Pierre-Yves Marie, Stéphane Renaud, Antoine Verger
Journal of Thoracic Disease  
2026;
18
(6)
:593
.
 (30 June 2026) 
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A bibliometric analysis of post-translational modifications in esophageal cancer based on the Web of Science Core Collection database [2000–2026]
Fan Gao, Xiaokang Gong
Journal of Thoracic Disease  
2026;
18
(6)
:594
.
 (30 June 2026) 
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Optimal surgical timing for atrial functional mitral regurgitation based on preoperative diuretic requirement: a retrospective cohort study
Kazuma Handa, Shin Yajima, Yusuke Yanagino, Yumi Kakizawa, Daisuke Yoshioka, Takuji Kawamura, Ai Kawamura, Yusuke Misumi, Ryoto Sakaniwa, Shunsuke Saito, Shigeru Miyagawa
Journal of Thoracic Disease  
2026;
18
(6)
:595
.
 (30 June 2026) 
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CT-based deep learning predicts immunotherapy response in esophageal squamous cell cancer patients
Tongxin Li, Rutao Fan, Zhili Liu, Shanshan Xu, Xiaoqin Zhang, Zhou Xu, Jian Yi, Ziyan Wei, Wei Wu, Yi Wu
Journal of Thoracic Disease  
2026;
18
(6)
:596
.
 (30 June 2026) 
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Diagnostic uncertainty and addiction-like reassurance seeking in patients with pulmonary nodules: a cross-sectional study
Shangqing Xu, Yan Sun, Xiaoyan Han, Kexin Ma, Yu Gu, Hongying Jin, Xiaoli Ma, Minjie Ma
Journal of Thoracic Disease  
2026;
18
(6)
:597
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 (30 June 2026) 
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CT-derived thoracic muscle thickness is associated with prolonged hospitalization after video-assisted thoracoscopic surgery
Michael Mosebetsi Moleka, Shuqi Jia, Wanli Jiang
Journal of Thoracic Disease  
2026;
18
(6)
:598
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 (30 June 2026) 
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GAN-generated target reconstruction CT radiomics for prediction of the novel IASLC grading of pulmonary adenocarcinoma
Qinling Jiang, Wei Deng, Xin’ang Jiang, Hongbiao Sun, Xiang Wang, Xianpan Pan, Zirui Cao, Gang Xiang, Ya Wen, Qi Chen, Yuxin Cheng, Tianyi Xing, Lei Chen, Yi Xiao
Journal of Thoracic Disease  
2026;
18
(6)
:599
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 (30 June 2026) 
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TikTok, Xiaohongshu, and Bilibili as sources of medical information on lung cancer: a multi-platform content evaluation
Jian Ding, Yikun Cheng, Weizhen Guo, Qian Xue, Cheng Yang, Zegeng Li
Journal of Thoracic Disease  
2026;
18
(6)
:600
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 (30 June 2026) 
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Predicting the progression risk of chronic obstructive pulmonary disease in high-risk individuals based on whole-lung radiomics and deep learning: a multicenter study
Jianfei Lin, Yan Zhang, Sheng Lu, Hongxing Zhao, Chentao Zhu, Huifang Du, Yifeng Zheng, Hupo Bian, Haifeng Qian
Journal of Thoracic Disease  
2026;
18
(6)
:601
.
 (30 June 2026) 
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Ultra fast track anesthesia in acute Stanford type A aortic dissection surgery: a single-center retrospective study
Yi-Fan Zou, Fang-Ting Xie, Bo Wang, Hao Yao
Journal of Thoracic Disease  
2026;
18
(6)
:602
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 (30 June 2026) 
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Research progress and trends on DNA methylation research in non-small cell lung cancer: a bibliometric analysis
Mengmeng Chen, Yaming Liu, Fengfeng Xu, Jincan Zhang, Congwen Zhuang, Meiqing Zhang, Kaixiang Zhang
Journal of Thoracic Disease  
2026;
18
(6)
:603
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 (30 June 2026) 
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Tripterygium wilfordii glycoside tablets ameliorate interstitial pulmonary fibrosis via regulating TGF-β/IL-17 signaling and Th17-mediated inflammatory response
Liming Chen, Shuping Cheng, Pengcheng Liu, Juan Jiang, Houhui Jiang, Rui Wu, Shujiao Yu
Journal of Thoracic Disease  
2026;
18
(6)
:604
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 (30 June 2026) 
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Prognostic value of perioperative inflammatory biomarkers in patients undergoing surgical resection for non-small cell lung cancer
Jianxin Cai, Jiahua Tu, Ronglong Lin, Jianxin Xu
Journal of Thoracic Disease  
2026;
18
(6)
:605
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 (30 June 2026) 
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C1ORF112 drives lung adenocarcinoma progression through e2f8-mediated transcriptional activation
Jingsi Wang, Guixue Yang, Xufeng Deng, Xiaobing Liu, Dan Chen, Quanxing Liu
Journal of Thoracic Disease  
2026;
18
(6)
:606
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 (30 June 2026) 
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Feasibility and safety of awake extracorporeal membrane oxygenation for operating room extubation after lung transplantation
Chengfu Xian, Lihua Ao, Shangxi Zeng, Jiayu Li, Zhuolin He, Shujun Wu, Furong Lin, Fengfa Yang, Lan Lan
Journal of Thoracic Disease  
2026;
18
(6)
:607
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 (30 June 2026) 
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A decreased postoperative basophil percentage is an independent risk factor for prognosis in patients with lung cancer
Bingyuan Zhou, Jutong He, Shixue Zhang, Wen Wang, Zhaokai Huang, Ming Xu, Hexiao Tang
Journal of Thoracic Disease  
2026;
18
(6)
:608
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 (30 June 2026) 
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Prognostic value of pretreatment systemic immune-inflammation index for overall survival in esophageal squamous cell carcinoma in China: a systematic review and meta-analysis
Chenghai He, Kexin Chen, Yu Zhao, Liwei Ni, Ruonan He, Yaping Zhang, Nanting Sun, Guodong Li, Zhichao Lai
Journal of Thoracic Disease  
2026;
18
(6)
:609
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 (30 June 2026) 
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Real-time thoracic duct visualization in lung cancer surgery: feasibility of indocyanine green fluorescence imaging via inguinal lymph node injection
Jian-Ping Huang, Yuan Chen, Yi-Zhuo Hu, Yan-Ming Zhu, Hao Ding, Qi-Fan Li, Yuan Cui, Jun Chen
Journal of Thoracic Disease  
2026;
18
(6)
:610
.
 (30 June 2026) 
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Development and validation of prediction model for intrapulmonary metastasis in lung adenocarcinoma based on machine learning
Zhenglong Wang, Xiaobo Liu, Mingyue Zhang
Journal of Thoracic Disease  
2026;
18
(6)
:611
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 (30 June 2026) 
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A single-center study on prosthesis selection strategy in aortic valve replacement for patients aged 50–65 years
Jia Sun, Yuqiu He, Xinyi Mao, Xiaofei Han, Junyi Hu, Ziang Zhou, Yuming Huang, Yongfeng Shao, Yefan Jiang
Journal of Thoracic Disease  
2026;
18
(6)
:612
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 (30 June 2026) 
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Construction and validation of a machine learning-based prediction model for in-hospital acute kidney injury in patients with lung cancer complicated with sepsis: clinical and nursing applications
Huiping Zhang, Jinyan Zhang
Journal of Thoracic Disease  
2026;
18
(6)
:613
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 (30 June 2026) 
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Impact of non-pharmacological adjuvant interventions on adult asthma patients: a systematic review and network meta-analysis
Rui Mao, Yujia Liu, Yuying Li
Journal of Thoracic Disease  
2026;
18
(6)
:614
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 (30 June 2026) 
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Development and validation of a clinically interpretable risk scoring system for predicting one-year all-cause mortality in esophageal cancer: a population-based study
Handan Lin, Mengke Ma, Wendi Fei, Qinsheng Lu, Bin He
Journal of Thoracic Disease  
2026;
18
(6)
:615
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 (30 June 2026) 
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Female sex is associated with improved survival after perioperative immunotherapy in resectable non-small cell lung cancer
Vikram Krishna, Claire Perez, Kellie Knabe, Bryan Navarro, Raffaele Rocco, Andrew R. Brownlee, Clark Fuller, Harmik J. Soukiasian, Philicia Moonsamy
Journal of Thoracic Disease  
2026;
18
(6)
:616
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 (30 June 2026) 
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First-line third-generation EGFR-TKIs for advanced EGFR-mutated non-small cell lung cancer: a systematic review and network meta-analysis of randomized controlled trials
Xiaomin Liu, Qingfang Zhao, Wei Sun, Jinglong Chen
Journal of Thoracic Disease  
2026;
18
(6)
:617
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 (30 June 2026) 
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Thoracic SMARCA4-deficient undifferentiated tumor: a systematic review and meta-analysis of individual patient data with cross-cohort survival comparison
Zhuoying Su, Guiyang Chen, Fengmei Zhong, Bin Liu, Shuhong Wu, Fu Rong, Yanhua Lv, Xi Li
Journal of Thoracic Disease  
2026;
18
(6)
:618
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 (30 June 2026) 
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Global trends and inequalities in environmental risk-attributable chronic obstructive pulmonary disease mortality among adults aged 80+ years, 1990–2021: an analysis of the Global Burden of Disease Study 2021
Yan Wang, Shuai Jiang, Chengzeng Wang
Journal of Thoracic Disease  
2026;
18
(6)
:619
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 (30 June 2026) 
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Emerging trends and hotspots in lung-protective ventilation from 2006 to 2025: a bibliometric analysis
Shenqi Wang, Chen Xie, Xinchen Tao, Tao Liu
Journal of Thoracic Disease  
2026;
18
(6)
:620
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 (30 June 2026) 
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Clinical characteristics and surgical outcomes of uniportal video-assisted thoracoscopic surgery for lung cancer patients with concomitant pulmonary tuberculosis: a retrospective cohort study
Kangbao Kong, Dawei Liu, Gaofeng Qiao, Jiankun Zhu, Yunzeng Zhang
Journal of Thoracic Disease  
2026;
18
(6)
:621
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 (30 June 2026) 
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Micro-CT dynamic changes and molecular mechanisms in a pulmonary nodule mouse model induced by Benzo[a]pyrene and lipopolysaccharide
Dong Shao, Yakun Zhao, Keyu Zhang, Yujia Zheng, Peng Zhao, Yange Tian, Miao Zhou, Jiansheng Li
Journal of Thoracic Disease  
2026;
18
(6)
:622
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 (30 June 2026) 
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Gravity-driven modified whole-lung lavage improves procedural efficiency in pulmonary alveolar proteinosis
Weizhan Luo, Junfeng Huang, Xinyu Song, Changhao Zhong, Xiaobo Chen, Chunli Tang, Liya Lu, Yu Chen, Shiyue Li
Journal of Thoracic Disease  
2026;
18
(6)
:623
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 (30 June 2026) 
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A bibliometric analysis of lung cancer and atrial fibrillation [1991–2026]: research hotspots, thematic evolution, and translational landscape in cardio-oncology
Zongrong Lin, Sicheng Chen, Yang Liu, Hongcheng Chen, Yining Dai, Haomin Xie, Wenliang Wang, Daofu Huang, Zhenyang Fu
Journal of Thoracic Disease  
2026;
18
(6)
:624
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 (30 June 2026) 
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Association of mean blood glucose, glycemic variability, and their combined effect with 28-day mortality in critically ill ICU patients with acute myocardial infarction: a MIMIC-IV retrospective cohort study
Xinlin Luo, Jun Zhou, Fenghuan Hu, Dongzhou Liu
Journal of Thoracic Disease  
2026;
18
(6)
:625
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 (30 June 2026) 
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Balloon-expandable trilayer nitrided iron/Zn/poly-D,L-lactic acid metallic tracheal stent: structural characterization, mechanical performance, and short-term safety evaluation in rabbits
Hao Wang, Qiqi Hu, Wenxin Cao, Zihao Bai, Wanxuan Song, Xingtong Chen, Di Yu, Zhaocong Yang, Huilin Li, Chen Chen, Yuzhong Yang, Xuming Mo
Journal of Thoracic Disease  
2026;
18
(6)
:626
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 (30 June 2026) 
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Identification of neutrophil extracellular traps-related genes as feature genes and potential therapeutic targets in pulmonary hypertension
Fangwei Li, Xiaohong Ma, Ruxuan Li, Binbin Li, Qi Zhang
Journal of Thoracic Disease  
2026;
18
(6)
:627
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 (30 June 2026) 
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Small-cell transformation of advanced non-small-cell lung cancer harboring driver mutations following tyrosine kinase inhibitor therapy: a multicenter real-world study
Yuhai Lu, Xiaoliang Kang, Qiang Xu, Yu Zhou, Changbo Li, Hongxia Hu, Mao Chen
Journal of Thoracic Disease  
2026;
18
(6)
:628
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 (30 June 2026) 
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Mapping the evolution of sepsis and intestinal epithelial barrier research: a bibliometric analysis (1977–2024)
Zi Ge, Yao Zhang, Ke Ma, Zhijie Xia, Jun Cao, Hui Zhao, Jiaxin Hu
Journal of Thoracic Disease  
2026;
18
(6)
:629
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 (30 June 2026) 
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Diagnostic value of ocular imaging biomarkers in chronic obstructive pulmonary disease: a multicenter prospective cross-sectional study
Yunpeng Xu, Yanru Chen, Cuifang He, Lei Zhu, Jian Liu
Journal of Thoracic Disease  
2026;
18
(6)
:630
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 (30 June 2026) 
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Development and validation of an interpretable machine learning model for predicting sepsis risk in pleural effusion patients
Guanghao Pan, Wenhao Wang, Guang Yang, Huining Liu
Journal of Thoracic Disease  
2026;
18
(6)
:631
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 (30 June 2026) 
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Preoperative percutaneous transthoracic needle biopsy and pleural recurrence after curative resection for stage I non-small cell lung cancer: a systematic review and meta-analysis
Shangqing Xu, Kexin Ma, Xiaoyan Han, Ning Wei, Yan Sun, Hongying Jin, Huiling Li, Minjie Ma
Journal of Thoracic Disease  
2026;
18
(6)
:632
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 (30 June 2026) 
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Epidemiological patterns of pulmonary hypertension at 3,658 meters: insights from a Tibet plateau retrospective study
Quzhen Gesang, Zhuoga Danzeng, Yangzong Suona, Qin Luo, Qucuo Meilang, Ciren Dawa, Zhuoga Baima, Ju Huang, Luobu Gesang
Journal of Thoracic Disease  
2026;
18
(6)
:633
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 (30 June 2026) 
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Prognosis comparison and prognostic model construction in patients with Siewert type II adenocarcinoma of the esophagogastric junction after neoadjuvant therapy between proximal gastrectomy and total gastrectomy
Guoyi Shen, Pubo Shi, Pengjie Yang, Benben Zhu, Yong Li, Shuchen Chen
Journal of Thoracic Disease  
2026;
18
(6)
:634
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 (30 June 2026) 
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Multicenter, real-world patient registry outcomes from intercostal nerve cryoablation during robotic-assisted thoracic surgical procedures
Lizabeth A. O’Connor, Michael Gibson, Julian Guitron, Colleen Gaughan, Brett Grizzell, Curtis C. Quinn
Journal of Thoracic Disease  
2026;
18
(6)
:635
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 (30 June 2026) 
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Prediction of one-year post-discharge mortality in patients with acute exacerbation of chronic obstructive pulmonary disease based on clinical characteristics, blood gas indicators, and duration of non-invasive ventilation
Li-Na Huang, Xiao-Hong Zhu, Jin-Mei He
Journal of Thoracic Disease  
2026;
18
(6)
:636
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 (30 June 2026) 
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Perioperative timing of surgically implanted microaxial flow pump support in high-risk coronary artery bypass grafting: a single-center Society of Thoracic Surgeons study
Maria Guadalupe Lopez-Trevino, Fatima Qamar, Marcell Szekely, Istvan Gecse, Ashley B. Chuong, Michael J. Reardon, Mahesh Ramchandani, Ziyab Sarfaraz, Andrea Quarti, Fernando Ramirez-Del Val
Journal of Thoracic Disease  
2026;
18
(6)
:637
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 (30 June 2026) 
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SMARCA4 deficiency contributes to platinum resistance in non-small cell lung cancer by activating the NF-κB-BIRC2/BIRC3 signaling axis
Yufeng Li, Na Zhou, Lin Zhang, Xingfa Huo, Yuming Zhang, Fangfang Yang, Xuchen Zhang, Chuantao Zhang, Dantong Sun, Helei Hou
Journal of Thoracic Disease  
2026;
18
(6)
:638
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 (30 June 2026) 
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Improving postoperative pain management after minimally invasive coronary surgery using methadone analgesia and early chest drain removal
De Qing F. N. Görtzen, Fleur Sampon, Marjolein Hoefeijzers, Thibaud A. J. van den Bouwhuysen, Bart Koene, Joost F. J. Ter Woorst, Ferdi Akca
Journal of Thoracic Disease  
2026;
18
(6)
:639
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 (30 June 2026) 
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Burden of chronic obstructive pulmonary disease, related heart failure and risk factors among middle-aged and elderly patients, 1990–2050
Jingwei Chai, Ning Ding, Jing Qu, Dongdong Wang, Sen Yang, Jingjing Qian, Xiang Li, Fanyu Bu, Jing Wang, Shuang Feng, Honggang Xue
Journal of Thoracic Disease  
2026;
18
(6)
:640
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 (30 June 2026) 
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Early and late outcomes of surgical aortic valve replacement with or without aortic annular enlargement in patients with small aortic annulus: an exploratory comparison of Y-incision versus Manouguian techniques
Kairui Qu, Jiaxi Gu, Yongfeng Shao
Journal of Thoracic Disease  
2026;
18
(6)
:641
.
 (30 June 2026) 
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Metastasectomy versus stereotactic body radiotherapy for lung metastases: a systematic review and meta-analysis of reconstructed time-to-event data on overall and progression-free survival
Angelique Runkel, Tulio Caldonazo, Hristo Kirov, Lukas Mayer, Felipe S. Passos, Murat Mukharyamov, Johannes Fischer, Aryan Dadashzadeh K, Tim Sandhaus, Torsten Doenst, Patrick von Samson-Himmelstjerna
Journal of Thoracic Disease  
2026;
18
(6)
:642
.
 (30 June 2026) 
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Pulmonary cavitation as a dominant prognostic indicator in tuberculosis complicated by chronic pulmonary aspergillosis: a retrospective cohort study
Fen Gao, Fuming Zhao, Zhuo Zhang, Qian Li, Xingming Ye
Journal of Thoracic Disease  
2026;
18
(6)
:643
.
 (30 June 2026) 
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Myeloprotection effect of trilaciclib in lung cancer patients undergoing chemotherapy: a real-world retrospective study
Mingming Wang, Yalong He, Daihan Dong, Liang Han, Hong Yan, Xuyu Cui, Yong Zhang, Fang Zhang, Liqiang Song, Shuoyao Qu
Journal of Thoracic Disease  
2026;
18
(6)
:644
.
 (30 June 2026) 
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Ascending aortic versus axillary artery cannulation in Stanford type A aortic dissection repair: a propensity score-weighted cohort study
Yutian Sun, Hao Chen, Xiangyou Sun, Wei Yuan, Jing Zhang, Jun Zhou, Jiamin Yu, Yongjia Pei, Haibo Wu
Journal of Thoracic Disease  
2026;
18
(6)
:645
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 (30 June 2026) 
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A comparative evaluation of large language models in aligning with European Respiratory Society (ERS) guidelines for high-flow nasal cannula in acute respiratory failure
Hongxia Wu, Lumeng Lu, Yangyang Guo, Shuai Wang, Chengqi Dong, Xu Qiu, Dong Liang, Qiongya Mo, Wen Wang, Yiwei Li, Renjun Yang, Liyang Chang, Yunxing Yang, Xiaoxue Dong, Jiayi Deng, Haifang Zhou, Hanbin Wang
Journal of Thoracic Disease  
2026;
18
(6)
:646
.
 (30 June 2026) 
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Association of proton pump inhibitor use with clinical outcomes in patients with advanced non-small cell lung cancer receiving immune checkpoint inhibitors
Han Ma, Xiaoxia Lyu, Shichun Lu, Xiaolin Wang, Chao Sun, Yusheng Shu
Journal of Thoracic Disease  
2026;
18
(6)
:647
.
 (30 June 2026) 
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Usefulness of the multimodal biopsy approach in radial endobronchial ultrasound biopsy for peripheral lung lesions: a single center retrospective study
Donghyun Lee, Chul Park, Ganghee Chae, Jin Hyoung Kim, Seung Won Ra, Kwang Won Seo, Yangjin Jegal, Jong Joon Ahn, Mun-kwon Jang, Hee Won Son, Hee Yun Seol, Taehoon Lee
Journal of Thoracic Disease  
2026;
18
(6)
:648
.
 (30 June 2026) 
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Risk model based on adenylate uridylate (AU)-rich elements genes for assessing esophageal cancer prognosis and immune landscape
Chaofan Mao, Mingjiang Huang, Jianyang Ding, Bin Huang, Xuyang Peng, Xuhui Wu
Journal of Thoracic Disease  
2026;
18
(6)
:649
.
 (30 June 2026) 
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Adaptive Fourier decomposition-based time-frequency analysis of COVID-19 epidemic trends and policy interventions in Washington D.C., with comparative validation in London
Kerui Cen, Xuanfeng Li, Guibin Lu, Yiping Li, Yangqianxi Wang, Zhiqi Zeng, Zifeng Yang, Xiaoyan Deng, Chitin Hon
Journal of Thoracic Disease  
2026;
18
(6)
:650
.
 (30 June 2026) 
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Dangerous liaisons: the peri-transplant respiratory microbiota and their impact on lung transplantation outcomes
Maximilian Vorstandlechner, Julia Walter, Mara A. Bauer, David Steybe, Jan M. Fertmann, Christian P. Schneider, Sebastian Michel, Jürgen Barton, Ines Schroeder, Gökce Yavuz, Olaf M. Glueck, Alexandra Weber, Wenko Smolka, Teresa Kauke, Katharina Theresa Obermeier
Journal of Thoracic Disease  
2026;
18
(6)
:651
.
 (30 June 2026) 
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Risk and mediation analysis of early β-blocker use on survival outcomes in sepsis patients and new-onset atrial fibrillation: an analysis of the MIMIC-IV database
Tingting Xie, Yi Yu, Linbao Sheng, Li Li, Jian Li
Journal of Thoracic Disease  
2026;
18
(6)
:652
.
 (30 June 2026) 
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Tumor-associated collagen signature in relation to metastasis in lung adenocarcinoma
Michael H. Udin, Sarmila Nepali, Swati Sonkawade, Scott T. Doyle, Ciprian N. Ionita, Yongdong Ouyang, Umesh C. Sharma, Saraswati Pokharel
Journal of Thoracic Disease  
2026;
18
(6)
:653
.
 (30 June 2026) 
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Canine radiography and echocardiography sensor fusion for deep learning-based detection and classification of myxomatous mitral valve disease
Kobkarn Thepsupornkul, Sirilak Disatian Surachetpong, Alisa Kunapinun, Matthew N. Dailey
Journal of Thoracic Disease  
2026;
18
(6)
:654
.
 (30 June 2026) 
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Mediastinal lymph node metastasis pattern of subsolid non-small cell lung cancer
Xiao Sun, Yanlu Xin, Yanjun Jia, Hao Wang, Xiangyu Cui, Jun Chen
Journal of Thoracic Disease  
2026;
18
(6)
:655
.
 (30 June 2026) 
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Effects of prehabilitation on outcomes among patients undergoing surgery for lung cancer: a systematic review and meta-analysis of randomized controlled trials
Dan Li, Yan Lv, Rui Wang, Jiaqi Li, Yanqiang Zhang, Yanni Rong, Xiaona Li, Le Gao
Journal of Thoracic Disease  
2026;
18
(6)
:656
.
 (30 June 2026) 
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Transmembrane mucin 21 drives lung adenocarcinoma growth by suppressing retinoic acid receptor β signaling
Weibin Lv, Xiang Huang, Xiangwei Cheng, Yifan Wang, Linfeng Wu, Yiping Zhu
Journal of Thoracic Disease  
2026;
18
(6)
:657
.
 (30 June 2026) 
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Online symptom monitoring for lung cancer patients receiving systemic therapy: a feasibility implementation project
Sarah Reddy, Andrea Gibson, Rosemary Peacock, Christopher Bedding, Cheryl Armstrong, Robert Carter, Katy Clarke, Rosie McDonald, Majid Riaz, Galina Velikova
Journal of Thoracic Disease  
2026;
18
(6)
:658
.
 (30 June 2026) 
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Fagopyrum acutatum extract attenuates influenza A virus-stimulated inflammation and acute lung injury in vitro and in vivo
Jinbing Liu, Yingxuan Zhou, Hanwei Huang, Conglin Li, Jiayi Ke, Lifu Liu, Yintong Chen, Taotao Gao, Xiaoli Liang, Youhua Xu, Zifeng Yang
Journal of Thoracic Disease  
2026;
18
(6)
:659
.
 (30 June 2026) 
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Determinants of single‑pass specimen adequacy in endobronchial ultrasound-guided transbronchial needle aspiration: a real-world study
Yajuan Qian, Yongkang Huang, Xiaoliang Zhu, Yong Yu, Ziyan Du, Zengli Zhang
Journal of Thoracic Disease  
2026;
18
(6)
:660
.
 (30 June 2026) 
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Optimal drug regimens for squamous non-small cell lung cancer: a systematic review and a Bayesian network meta-analysis of randomized trials
Yan Ye, Yaqian Li, Nuoyu Yan, Lan Sun
Journal of Thoracic Disease  
2026;
18
(6)
:661
.
 (30 June 2026) 
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High-flow nasal cannula oxygen versus Venturi facemask in women with cardiovascular disease undergoing cesarean delivery under neuraxial anesthesia: a randomized controlled trial
Xiaorui Zhou, He Jing, Jiakai Lu, Jinglan Zhang, Dawei Zhang, Yuqiu Lu, Peirong Lin, Shuwen Li, Mu Jin, Sheng Wang
Journal of Thoracic Disease  
2026;
18
(6)
:662
.
 (30 June 2026) 
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Real world comparative outcomes of adjuvant carboplatin versus cisplatin-based chemotherapy in stage IB–IIIA non-small cell lung cancer: a propensity-weighted analysis
Molly Tokaz, Brendan T. Heiden, Daniel B. Eaton Jr, Shadia Jalal, Nahom Seyoum, Whitney S. Brandt, Nikki E. Rossetti, Su-Hsin Chang, Yan Yan, Varun Puri, Martin W. Schoen, Theodore S. Thomas
Journal of Thoracic Disease  
2026;
18
(6)
:663
.
 (30 June 2026) 
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Increased rates of surgical resection of early-stage small cell lung cancer in a single-institution cohort
Sora Ely, Justin M. Bader, Brooks Van Udelsman, Emily June Zolfaghari, Anne C. Chiang, William de Santis, Shawn Reginauld, Andrew P. Dhanasopon, Robert Homer, Guoping Cai, Gavitt Alida Woodard
Journal of Thoracic Disease  
2026;
18
(6)
:664
.
 (30 June 2026) 
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Integrative single-cell and bulk transcriptomic analyses identify IGFBP2 within a peri-anesthetic stress-related gene framework linked to injury/transitional remodeling of alveolar type II cells in idiopathic pulmonary fibrosis
Jinxiang Yu, Xiaochuan Feng, Haikun Zhang, Lifeng Jia, Pengcheng Ma, Le Cao, Nianliang Zhang, Tao Zhao
Journal of Thoracic Disease  
2026;
18
(6)
:665
.
 (30 June 2026) 
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Efficacy of cemiplimab in biomarker defined subgroups of non-small cell lung cancer: a systematic review and meta-analysis
Yuanyuan Wang, Jianfei Wang, Shuangqing Liu, Haipeng Zhang, Yang Cao
Journal of Thoracic Disease  
2026;
18
(6)
:666
.
 (30 June 2026) 
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Preoperative prediction of lymph node metastasis in lung adenocarcinoma based on tumor size and carcinoembryonic antigen
Tao Lin, Jian Zhao, Feng Zhu, Tengfei Ge, Lei Tang, Dan Liu, Lu Wang, Hua Guo, Peng Qian, Wenglong Zhang, Xianbao Cao, Dongchun Ma
Journal of Thoracic Disease  
2026;
18
(6)
:667
.
 (30 June 2026) 
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Integrated hypoxia and metabolic gene signature to predict clinical outcomes and therapeutic vulnerabilities in lung adenocarcinoma
Yuquan Ma, Mengmeng Yang, Zhitao Sun, Fei Liu, Boying Zheng, Yanwei Wang, Junfeng Liu
Journal of Thoracic Disease  
2026;
18
(6)
:668
.
 (30 June 2026) 
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Brief Report

Safety and pathologic response of neoadjuvant pulsed electric field ablation and systemic therapy in early-stage resectable lung cancer: case series
Janani S. Reisenauer, David M. DiBardino, Gerard J. Criner, Stephen J. Hunt, Joseph Panaro, Joseph Friedberg, Aaron S. Mansfield, Charu Aggarwal, J. Nicholas Bodor, Matthew R. Callstrom
Journal of Thoracic Disease  
2026;
18
(6)
:669
.
 (30 June 2026) 
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A novel technique using diode laser-assisted endobronchial ultrasound-guided transbronchial biopsy: a brief report
Ashish Jain, Jonathan Munoz, Anthony Vaccarello, Elio Feghali, Khaled Abdullah, Tarek Dammad
Journal of Thoracic Disease  
2026;
18
(6)
:670
.
 (30 June 2026) 
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Study Protocol

Induction therapy of pralsetinib followed by conversion surgery for unresectable locally advanced non-small cell lung cancer with the rearranged during transfection (RET) fusion gene mutation: protocol for a single-arm phase II prospective trial (the SALVAGE-P trial)
Han-Yu Deng, Xiao-Ming Qiu, Lu Li, Xiao-Jun Tang, Qinghua Zhou
Journal of Thoracic Disease  
2026;
18
(6)
:671
.
 (30 June 2026) 
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Review Article

The role of radiologic assessment in evaluating and monitoring respiratory function in amyotrophic lateral sclerosis (ALS) patients: a narrative review
Bimaje Akpa
Journal of Thoracic Disease  
2026;
18
(6)
:672
.
 (30 June 2026) 
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Vaping-related lung disease: a narrative review
Christie Mellor, Richard Davidson, Benjamin Pippard
Journal of Thoracic Disease  
2026;
18
(6)
:673
.
 (30 June 2026) 
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Lung hernia: an updated narrative review
Vladislav Muldiiarov, Mark Shacker, Sreeja Biswas Roy, Rajat Walia, Samad Hashimi, Michael A. Smith, Lara Schaheen, Ross M. Bremner, Ashwini Arjuna
Journal of Thoracic Disease  
2026;
18
(6)
:674
.
 (30 June 2026) 
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Post pneumonectomy syndrome: a narrative review of current management strategies
Ethyn G. Loreno, Min P. Kim
Journal of Thoracic Disease  
2026;
18
(6)
:675
.
 (30 June 2026) 
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Evolution and refinements in minimally invasive esophagectomy: a narrative review
Emma Jacobs, Hiran C. Fernando
Journal of Thoracic Disease  
2026;
18
(6)
:676
.
 (30 June 2026) 
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Application of confocal laser endomicroscopy in the diagnosis of peripheral pulmonary lesions: a narrative review
Ziyun Wu, Chunxi Zhang, Fangfang Xie, Junxiang Chen, Haoran Ding, Jiayuan Sun
Journal of Thoracic Disease  
2026;
18
(6)
:677
.
 (30 June 2026) 
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Exercise-induced gut microbiota metabolites and the gut-lung axis: implications for chronic obstructive pulmonary disease
Zhiwei Fan, Jun Chen, Junyi Fang, Weiyi Yan, Weibing Wu
Journal of Thoracic Disease  
2026;
18
(6)
:678
.
 (30 June 2026) 
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Response-adapted perioperative therapy for resectable esophageal cancer in the immunotherapy era: a narrative review
Yuyang Yan, Jiahua Lyu, Yungchang Chen, Xuefeng Leng
Journal of Thoracic Disease  
2026;
18
(6)
:679
.
 (30 June 2026) 
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Connecting the dots: historical perspective on lung volume reduction
Avantika Nathani, Jean Luis Reinoso, Ashutosh Sachdeva, Tudor P. Toma, Atul C. Mehta
Journal of Thoracic Disease  
2026;
18
(6)
:680
.
 (30 June 2026) 
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Lung transplantation in 2025: a narrative review of progress, challenges, and the road ahead
Xiaohan Jin, Jiaqi Li, Yaling Liu, Audrey Yaulap Li, Jier Ma, Linxi Liu, Zhiqiang Deng, Zengwei Yu, Xiangyun Zheng, Haoji Yan, Qiang Pu, Lunxu Liu, Masaaki Sato, Dong Tian
Journal of Thoracic Disease  
2026;
18
(6)
:681
.
 (30 June 2026) 
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Beyond survival: empowering adults with congenital heart disease through communication and co-designed education
Hajar Habibi, Margarita Brida, Michael A. Gatzoulis
Journal of Thoracic Disease  
2026;
18
(6)
:682
.
 (30 June 2026) 
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Reducing the complications from community acquired pneumonia: a review
Krishan Bansal, Jodie Chalmers, David T. Arnold
Journal of Thoracic Disease  
2026;
18
(6)
:683
.
 (30 June 2026) 
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Recent advances in artificial intelligence across interventional pulmonology: a narrative review
Shaheen Rizly, Anthony Saleh, Keerthana Keshava, Noah Reisman, Stephen J. Peterson, Janice M. Ayuda, Jeremy A. Weingarten
Journal of Thoracic Disease  
2026;
18
(6)
:684
.
 (30 June 2026) 
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Pulmonary hypertension following lung transplant: a systematic review
Roudi Bachar, Dany Tager, Jana Berro, Neil Nero, Sameep Sehgal, Atul C. Mehta
Journal of Thoracic Disease  
2026;
18
(6)
:685
.
 (30 June 2026) 
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Research progress, translation-related challenges, and clinical prospects of surface-enhanced Raman spectroscopy in respiratory virus detection: a narrative review
Jiayang Wang, Lingyi Kong, Boyu Zhao, Shaoshuai Han, Zhenlin Wu
Journal of Thoracic Disease  
2026;
18
(6)
:686
.
 (30 June 2026) 
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Editorial Commentary

Targeting the diaphragm during weaning from mechanical ventilation
Bruno Valle Pinheiro, Lídia Maria Carneiro Fonseca, Erich Vidal Carvalho
Journal of Thoracic Disease  
2026;
18
(6)
:687
.
 (30 June 2026) 
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Keeping both lungs open during open-lung surgery: an impossible challenge?
Arnaud Gacouin, Jean-Marc Tadié
Journal of Thoracic Disease  
2026;
18
(6)
:688
.
 (30 June 2026) 
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Mechanical thrombectomy in intermediate-high risk pulmonary embolism: progress, promise, and remaining uncertainty
Orly Ran Sapir, Stanislav Henkin
Journal of Thoracic Disease  
2026;
18
(6)
:689
.
 (30 June 2026) 
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Refining first-line therapy in ALK-positive non-small cell lung cancer: final overall survival from the ALEX trial and an evolving treatment landscape
Mitchell Boshkos, Mitchell Parma, Eric K. Singhi
Journal of Thoracic Disease  
2026;
18
(6)
:690
.
 (30 June 2026) 
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PCSK9 inhibition after heart transplantation: how low does low-density lipoprotein cholesterol need to go for cardiac allograft vasculopathy prevention?
Michael Weis
Journal of Thoracic Disease  
2026;
18
(6)
:691
.
 (30 June 2026) 
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Beyond exon 19 and 21: positioning lazertinib and the next generation of strategies for uncommon EGFR mutations
Takayuki Takahama
Journal of Thoracic Disease  
2026;
18
(6)
:692
.
 (30 June 2026) 
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Redefining outcomes in esophageal cancer surgery: insights from longitudinal Medicare data
Thomas Birdas
Journal of Thoracic Disease  
2026;
18
(6)
:693
.
 (30 June 2026) 
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A decade within reach-but not the destination: transcatheter aortic-valve replacement durability beyond year 10
Jeffrey H. Shuhaiber
Journal of Thoracic Disease  
2026;
18
(6)
:694
.
 (30 June 2026) 
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Robotic mitral valve repair in the setting of mitral annular calcification: the value of repair, the valor of judgment
Rakesh M. Suri, Shaan A. Asif
Journal of Thoracic Disease  
2026;
18
(6)
:695
.
 (30 June 2026) 
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Mechanistic success and clinical neutrality: lessons from the OXICARD trial
Ioana Cozma, Emilie P. Belley-Côté, Jessica Spence
Journal of Thoracic Disease  
2026;
18
(6)
:696
.
 (30 June 2026) 
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Improving dermatological adverse events from amivantamab plus lazertinib: lessons from the COCOON trial
Tess Gillham, Federico Monaca, Raffaele Califano
Journal of Thoracic Disease  
2026;
18
(6)
:697
.
 (30 June 2026) 
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Heller myotomy in achalasia: clinical implications from long-term outcomes
Keerthana Kota, Christopher DuCoin
Journal of Thoracic Disease  
2026;
18
(6)
:698
.
 (30 June 2026) 
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Intraoperative recurrent laryngeal nerve monitoring in esophagectomy with lymphadenectomy
Femke E. Lammes, B. Feike Kingma, Jelle P. Ruurda, Richard van Hillegersberg
Journal of Thoracic Disease  
2026;
18
(6)
:699
.
 (30 June 2026) 
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Critical appraisal of open lung ventilation strategies in thoracic surgery: the role of PEEP and recruitment maneuvers
Andres Zorrilla-Vaca, Michael C. Grant, Matthew B. Allen
Journal of Thoracic Disease  
2026;
18
(6)
:700
.
 (30 June 2026) 
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Beta-blockers for prevention of atrial fibrillation in cardiac surgery
Marc-Olivier Fischer
Journal of Thoracic Disease  
2026;
18
(6)
:701
.
 (30 June 2026) 
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PD-L1 score among non-small cell lung cancer patients: are we holding out for a hero?
Gilson Gabriel Viana Veloso, Fernanda Telles Lins Taveira, Carlos Gil Ferreira
Journal of Thoracic Disease  
2026;
18
(6)
:702
.
 (30 June 2026) 
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Book Review

A guiding beacon for surgeon-scientists: book review of Surgeons’ Guide to Medical Writing
Jinlin Wu
Journal of Thoracic Disease  
2026;
18
(6)
:703
.
 (30 June 2026) 
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Letter to the Editor

Bronchodilator response in bronchiectasis: mind the gap between definition and clinical reality
Kang Li
Journal of Thoracic Disease  
2026;
18
(6)
:704
.
 (30 June 2026) 
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Refining the role of extended resection in multidisciplinary treatment for cT4b esophageal cancer
Tomoki Makino, Makoto Yamasaki, Shigeru Miyagawa, Hidetoshi Eguchi, Yuichiro Doki
Journal of Thoracic Disease  
2026;
18
(6)
:705
.
 (30 June 2026) 
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Retraction

Retraction: miR-107 inhibited malignant biological behavior of non-small cell lung cancer cells by regulating the STK33/ERK signaling pathway in vivo and vitro
Xueqiang Wei, Yujie Lei, Minjie Li, Guangqiang Zhao, Yongchun Zhou, Lianhua Ye, Yunchao Huang
Journal of Thoracic Disease  
2026;
18
(6)
:706
.
 (30 June 2026) 
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