The present issue of the Journal of Thoracic Disease is dedicated to Surgery of the Airway. This exciting field of thoracic surgery represents a major technical challenge that has registered a significant improvement over time, thus changing the modern approach to a number of benign and malignant diseases. Outlook for cure of benign tracheal and laryngotracheal stenoses and of neoplasms involving the airway has dramatically improved in recent years together with growing experience and progressive diffusion of reconstructive techniques.