Von Willebrand factor multimers during transcatheter aortic valve replacement—an additional clue for detecting post-procedural aortic regurgitation?

Severe aortic valvular stenosis is among the most common forms of valvular heart disease, with disabling symptoms and a poor prognosis if left untreated (1). Parallel to the ageing of the general population and the rise of overall life expectancy, an increasing prevalence of the disease can be observed, and a growing need to treat patients who are deemed unsuitable for traditional valve replacement owing to high calculated surgical risk or general frailty.