Challenges in assessing response of oesophageal cancer to neoadjuvant therapy, and the potential of composite PET-CT and multimodal metrics

We read with interest Dr. Włodarczyk and Professor Kużdżał’s appraisal of the potential for composite positron emission tomography-computed tomography (PET-CT) metrics to improve the assessment of oesophageal cancer to neoadjuvant therapy, in particular that of a new metric we recently described: metabolic nodal response (mNR) (1,2).