Right ventricular-pulmonary artery coupling—an emerging perspective in transcatheter aortic valve replacement

Since its approval in 2011 in high and prohibitive-surgical-risk patients, transcatheter aortic valve replacement (TAVR) has expanded its indication to intermediate-surgical-risk patients (1,2). Studies are underway to investigate its potential as a modality in low-surgical risk patients and establish an all-risk indication for TAVR for treatment of patients with severe symptomatic aortic stenosis. During this journey, TAVR has crossed many hurdles through refinements in risk stratification, operator experience, and technological advancements.