Review Article


Pneumothorax in sarcoidosis

Katerina Manika, Ioannis Kioumis, Konstantinos Zarogoulidis, Ioanna Kougioumtzi, Georgios Dryllis, Georgia Pitsiou, Nikolaos Machairiotis, Nikolaos Katsikogiannis, Sofia Lampaki, Antonis Papaiwannou, Bojan Zaric, Perin Branislav, Haidong Huang, Qiang Li, Paschalis Steiropoulos, Paul Zarogoulidis

Abstract

While sarcoidosis is a relatively common but often underdiagnosed disease, pneumothorax appears to be a rare clinical event observed mostly at the late stages of the disease course. The precise underlying mechanism of such complication is unclear and probably involves the formation of bullae due to bronchial obstruction and retraction-collapse of distracted lung tissue. Thoracoscopic bullectomy represent the preferred treatment option for recurrent pneumothoraces. The administration of corticosteroids for the treatment of pulmonary sarcoidosis may have a protecting effect for such recurrences, but remains a controversial issue.

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