Preface

Chronic obstructive pulmonary disease (COPD) is a world-wide problem that is increasing in prevalence. COPD is a chronic lung disease characterised by persistent airflow limitation that is not fully reversible. COPD is the third leading cause of death world-wide. It is a heterogeneous disease, with multiple aetiological factors, clinical phenotypes and comorbidities. Acute exacerbations and progressive decline in lung function contribute to symptoms and outcomes. It is vitally important that we develop a deeper understanding of this complex chronic disease, in order to enhance the preventive and therapeutic strategies for patients with COPD, with the ultimate goal of effective management using a “personalised medicine” approach.