Does less equal more? The curious issue of small-sized lung cancer

Lung cancer is the leading cause of cancer-related death and continues to be a major global health problem (1). Nevertheless, as a result of advances in imaging techniques and the introduction of screening programs, significant progress in early stage diagnosis and reduction in mortality is observed (2). The increasing detection numbers of early staged non-small cell lung cancer (NSCLC) elicit multiple questions concerning the appropriate treatment approach in these patients.