Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions (GenTAC) registry predicting predictors for aortic dissection: a new thought around the corner?

The multicenter prospective National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions (GenTAC) registry collects clinical and biological data from patients with aortic aneurysm and associated genetic conditions, including Marfan syndrome (MFS), Ehlers-Danlos syndrome, Loeys-Dietz syndrome, Turner syndrome, bicuspid aortic valve (BAV), and familial or premature (age <50 years) thoracic aortic aneurysm (TAA) (1). Patient enrollment began in November 2007 and the registry was born with the main objective to compare cross-sectional and longitudinal data on risk factors related to diagnosis, treatment, and outcome among groups of enrolled patients (1).