Reaping Wnt after calming Hippo: Wnt and Hippo signaling cross paths in lung cancer

It has become clear in recent years that many signaling pathways influence each other and work cooperatively to regulate biological processes, such as the generation of complex multicellular tissues, organs, and organisms. These complex interactions are the subject of systems biology, a young and still poorly established approach in defining the complexities of life and the intricate interactions of major signaling pathways (1).