Vol 9, No 11 (November 29, 2017): Journal of Thoracic Disease (Quantitative Imaging of Thoracic Diseases)


Natriuretic peptide-guided versus clinically guided therapy for chronic heart failure: careful expert clinical management can remove need for biomarker-tailored dosing adjustment
Renato De Vecchis
Admitting an elderly patient with solid tumor in the intensive care unit: what do we have to look for?
Carmen Silvia Valente Barbas, Ellen Pierre de Oliveira, João Valente Barbas Filho
Editorial on “Transcription factor SPZ1 promotes TWIST-mediated epithelial—mesenchymal transition and oncogenesis in human liver cancer”
Dan J. Raz
The role of sublobar resections in the treatment of early stage non-small cell lung cancer—still awaiting evidence
Robert Dziedzic
The step forward for VA ECMO: left ventricular unloading!
Paolo Meani, Federico Pappalardo
Central sleep apnea during continuous positive airway pressure therapy in obstructive sleep apnea patients: from the compliance to adaptation, maladaptation and reflexes
Carolina Lombardi, Sergio Caravita, Gianfranco Parati
Prophylactic cranial irradiation or no prophylactic cranial irradiation in metastatic small cell lung cancer: is it a relevant question once again?
Cecile Le Pechoux, Angela Botticella, Antonin Levy, Anne Auperin
Transcriptional programs of tumor infiltrating T-cells provide insight into mechanisms of immune response and new targets for immunotherapy
Donovan Watza, Kristen S. Purrington, Kang Chen, Ann G. Schwartz
The new classifications for thymic epithelial tumors: benefits and problems
Takayuki Fukui, Kohei Yokoi
Complete mediastinal lymph node dissection versus systematic lymph node sampling in surgical treatment of non-small cell lung cancer: do we have the answer?
Yuzhao Wang, Gail E. Darling
Not like breast cancer, but like breast cancer: micrometastasis and micropapillary structure in lung cancer
Katsuhiro Masago, Shiro Fujita, Yasushi Yatabe
Reaping Wnt after calming Hippo: Wnt and Hippo signaling cross paths in lung cancer
Thomas Andl, Yuhang Zhang
Tumor epithelial tumors: do we expect a brighter or a grey future?
Rolando M. D’Angelillo, Sara Ramella
Emergent central sleep apnea during CPAP therapy-clinical implications
M. Jeffery Mador
Early stage small cell lung cancer: very rare, but a surgical disease!
Eric Vallières
KEYNOTE-010: flash of a supernova (immune-checkpoint inhibitors) in second-line non-small cell lung cancer
Hidehito Horinouchi
Routine beta-blocker administration following acute myocardial infarction: why still an unsolved issue?
Stephane Noble, Marco Roffi
Surgical risk models: how they contribute to improvement of our treatments?
Janusz R. Włodarczyk, Jarosław Kużdżał
Tumor-associated macrophages—additional effectors at anti-PD-1/PD-L1 therapy?
Kenichi Suda
Do we still need pharmacological stress ulcer prophylaxis at the ICU?
Lukas Buendgens, Frank Tacke
Seeing is believing: visualization of pulmonary vein gaps using ultra-high resolution electroanatomic mapping
Chin-Yu Lin, Fa-Po Chung, Yenn-Jiang Lin, Shih-Ann Chen
EGFR tyrosine kinase inhibitors as first-line therapy in advanced EGFR mutation-positive non-small cell lung cancer: strategies to improve clinical outcome
Andreas Tiefenbacher, Robert Pirker
Role of the modern radiotherapy in the postoperative setting for esophageal cancer
Gian-Carlo Mattiucci, Francesco Cellini
Pulmonary nodules and mini-invasive lung resection: do we have the right “tool” for their intraoperative localization?
Paola Ciriaco, Piergiorgio Muriana, Giampiero Negri
Coronary artery disease and myocardial revascularization in patients undergoing transcatheter aortic valve replacement
Raffaele Piccolo, Anna Franzone, Thomas Pilgrim
Percutaneous patent foramen ovale closure for cryptogenic stroke: learning from clinical trial and error
Mohammad K. Mojadidi, Ahmed N. Mahmoud, Islam Y. Elgendy
The future of immune checkpoint blockade immunotherapy: towards personalized therapy or towards combination therapy
Zhiwei Hu
Surgery compared to stereotactic body radiation therapy for earlystage non-small cell lung cancer: better, equivalent or worse?
Paul E. Van Schil
What is the optimal adjuvant therapy for T3N0 lung cancer invading the chest wall?
Makoto Suzuki, Takeshi Mori, Kenji Shiraishi, Koei Ikeda, Yoshiko Masuda, Eri Matsubara, Chika Shirakami, Hironori Hinokuma
Timing of invasive strategy in patients with non-ST-segment elevation acute coronary syndrome and effect on clinical outcomes
Vladan Vukcevic, Goran Stankovic
The role of Piccolo in cancer treatment: relationship with EGFR and related therapies, and a marker for new targeted therapies
Milo Frattini, Francesca Molinari, Samantha Epistolio
Establishing the entity of neonatal acute respiratory distress syndrome
Judith Ju-Ming Wong, Bin Huey Quek, Jan Hau Lee
Intratumoral heterogeneity and biomarkers for transformation into small cell lung carcinomas from lung adenocarcinomas
Hyun Lee, Sang-Won Um
Antithrombotic treatment following transcatheter valve replacement: current considerations
Ioanna Koniari, Nicholas G. Kounis, George Hahalis
Antithrombotic therapy after transcatheter aortic valve implantation: a new piece of the still unresolved puzzle
Giuseppe Gargiulo, Marco Valgimigli
Are specialized pro-resolving mediators promising therapeutic agents for severe bronchial asthma?
Takeshi Hisada, Haruka Aoki-Saito, Yasuhiko Koga
Extracapsular lymph node involvement in patients with esophageal cancer treated with neoadjuvant chemoradiation therapy followed by surgery: the closer you look, the less you see
Yin-Kai Chao
The extracorporeal membrane oxygenation (ECMO) high-fidelity simulator: the best complementary tool to learn the technique
Santiago Montero, Alain Combes, Matthieu Schmidt
Looking for sputum biomarkers in lung cancer secondary prevention: where are we now?
Nicola Fusco, Caterina Fumagalli, Elena Guerini-Rocco
Role of intrapulmonary lymph node retrieval for pathological examination in resectable non-small cell lung cancer
Apichat Tantraworasin, Emanuela Taioli, Sophon Siwachat, Somcharoen Saeteng
High-fidelity simulation for extracorporeal membrane oxygenation training, utile or futile?
Carlo Banfi, Karim Bendjelid, Raphaël Giraud
Pathologic N1 disease in lung cancer: the segmental and subsegmental lymph nodes
Marc Riquet, Ciprian Pricopi, Giuseppe Mangiameli, Alex Arame, Alain Badia, Françoise Le Pimpec Barthes
Vaccine against PCSK9: the natural strategy from passive to active immunization for the prevention of atherosclerosis
Fernando Civeira, Estíbaliz Jarauta
Exosomes: recruits for tumour surveillance?
Francesco Pezzella
Tumor microenvironment as a potential source of clinical biomarkers in non-small cell lung cancer: can we use enemy territory at our advantage?
Carlo Genova, Erika Rijavec, Francesco Grossi
Heparin versus bivalirudin for percutaneous coronary intervention: has the debate come to an end?
Islam Y. Elgendy, Davide Capodanno
Sputum-based DNA methylation biomarkers to guide lung cancer screening decisions
Delphine Lissa, Ana I. Robles
Status of lung cancer screening
James L. Mulshine
Different techniques in robotic lung resection
Pierluigi Novellis, Marco Alloisio, Umberto Cariboni, Giulia Veronesi
Minimally invasive resection and reconstruction of the intrathoracic trachea and carina
Gregor J. Kocher, Patrick Dorn
The price of innovation: a primer on high risk, high reward surgery
Alejandro Bribriesco, Usman Ahmad, Siva Raja

Original Article

Restrictive ventilatory impairment is associated with poor outcome in patients with cT1aN0M0 peripheral squamous cell carcinoma of the lung
Hiroyuki Tao, Junichi Soh, Hiromasa Yamamoto, Toshiya Fujiwara, Tsuyoshi Ueno, Makio Hayama, Mikio Okazaki, Ryujiro Sugimoto, Motohiro Yamashita, Yoshifumi Sano, Kazunori Okabe, Motoki Matsuura, Kazuhiko Kataoka, Shigeharu Moriyama, Shinichi Toyooka, Shinichiro Miyoshi
Short and long-term results of sternectomy for sternal tumours
Stefano Bongiolatti, Luca Voltolini, Sara Borgianni, Roberto Borrelli, Marco Innocenti, Giulio Menichini, Leonardo Politi, Giorgia Tancredi, Domenico Viggiano, Alessandro Gonfiotti
Postoperative pain in thoracic surgery: re-evaluating the benefits of VATS when coupled with epidural analgesia
Toshiro Obuchi, Yasuhiro Yoshida, Toshihiko Moroga, Naofumi Miyahara, Akinori Iwasaki
The methylation state of VDR gene in pulmonary tuberculosis patients
Chao Jiang, Junjie Zhu, Yuxiao Liu, Xidi Luan, Yan Jiang, Gening Jiang, Jiang Fan
Long-term survival after surgery for pulmonary metastases from colorectal cancer: an observational cohort study
Mamdoh Al-Ameri, Michael Persson, Per Bergman, Anders Franco-Cereceda, Ulrik Sartipy
A meta-analysis of late outcomes of mitral valve repair in patients with rheumatic heart disease
Jin-Tao Fu, Mohammad Sharif Popal, Hai-Bo Zhang, Wei Han, Qiu-Ming Hu, Xu Meng, Chun-Ye Ma
Doxycycline attenuates paraquat-induced pulmonary fibrosis by downregulating the TGF-β signaling pathway
Xu-Fang Hua, Xiao-He Li, Mi-Mi Li, Cheng-Yu Zhang, Hui-Juan Liu, Tao Sun, Hong-Gang Zhou, Cheng Yang
Volume doubling time of lung adenocarcinomas considering epidermal growth factor receptor mutation status of exon 19 and 21: three-dimensional volumetric evaluation
Rui Zhang, Bojiang Chen, Yongzhao Zhou, Ping Zhou, Jing Jin, Longchao Zhao, Weimin Li
Urban particulate matter triggers lung inflammation via the ROSMAPK- NF-κB signaling pathway
Jian Wang, Jianan Huang, Linlin Wang, Cuicui Chen, Dong Yang, Meiling Jin, Chunxue Bai, Yuanlin Song
Clinical implications of differentiating between types of post- tracheostomy tracheal stenosis
Beomsu Shin, Kang Kim, Byeong-Ho Jeong, Jung Seop Eom, Won Jun Song, Hojoong Kim
Replacement of calcified ascending aorta in patients undergoing aortic valve replacement
Hyoung Woo Chang, Dong Seop Jeong, Yang Hyun Cho, Kiick Sung, Wook-Sung Kim, Young Tak Lee, Pyo Won Park
Comprehensive investigation of clinicopathologic features, oncogenic driver mutations and immunohistochemical markers in peripheral lung squamous cell carcinoma
Yang Zhang, Difan Zheng, Yuan Li, Yunjian Pan, Yihua Sun, Haiquan Chen
The impact of extreme obesity on outcomes after left ventricular assist device implantation
Gardner Yost, Laura Coyle, Colleen Gallagher, Nicole Graney, Roxanne Siemeck, Antone Tatooles, Patroklos Pappas, Geetha Bhat
Pneumonectomy is safe and effective for non-small cell lung cancer following induction therapy
Abby White, Suden Kucukak, Raphael Bueno, Elliot Servais, Daniel N. Lee, Yolonda Colson, Michael Jaklitsch, Ciaran McNamee, Steven Mentzer, Jon Wee, Scott J. Swanson
Impact of major video-assisted thoracoscopic surgery on care quality
Florencio Quero Valenzuela, Inmaculada Piedra Fernández, Maria Del Carmen Martínez Cirre, Abel Sánchez-Palencia, Antonio Cueto Ladrón de Guevara
Prognostic significance and role in TNM stage of tumor deposits in esophageal cancer
Qi-Xin Shang, Yu-Shang Yang, Li-Yan Xu, En-Min Li, Wei-Peng Hu, Long-Qi Chen
Post-traumatic acute thoracic aortic injury (TAI)—a single center experience
Piotr Buczkowski, Mateusz Puslecki, Sebastian Stefaniak, Robert Juszkat, Jerzy Kulesza, Bartłomiej Perek, Marcin Misterski, Tomasz Urbanowicz, Marcin Ligowski, Bartosz Zabicki, Marek Dabrowski, Lukasz Szarpak, Marek Jemielity
Short-term inpatient-based high-intensive pulmonary rehabilitation for lung cancer patients: is it feasible and effective?
Kun Zhou, Jianhua Su, Yutian Lai, Pengfei Li, Shuangjiang Li, Guowei Che
Spontaneous ventilation anesthesia combined with uniportal and tubeless thoracoscopic lung biopsy in selected patients with interstitial lung diseases
Guilin Peng, Mengyang Liu, Qun Luo, Hanzhang Chen, Weiqiang Yin, Wei Wang, Jun Huang, Yuan Qiu, Zhihua Guo, Lixia Liang, Qinglong Dong, Xin Xu, Jianxing He
Rhinovirus is associated with severe adult community-acquired pneumonia in China
Keqiang Wang, Wen Xi, Donghong Yang, Yali Zheng, Yaqiong Zhang, Yusheng Chen, Chunliang Yan, Guizhen Tian, Shuchang An, Xiangxin Li, Fucheng An, Juan Du, Ke Hu, Jie Cao, Lili Ren, Fang Huang, Zhancheng Gao
Stereotactic body radiotherapy (SBRT) for pulmonary metastases from renal cell carcinoma—a multicenter analysis of the German working group “Stereotactic Radiotherapy”
Juliane Hoerner-Rieber, Marciana Duma, Oliver Blanck, Guido Hildebrandt, Andrea Wittig, Fabian Lohaus, Michael Flentje, Frederick Mantel, Robert Krempien, Michael J. Eble, Klaus Henning Kahl, Judit Boda-Heggemann, Stefan Rieken, Matthias Guckenberger
Pneumonectomy in pulmonary metastasis
Noriyuki Matsutani, Sakae Okumura, Ichiro Yoshino, Norihiko Ikeda, Yuichi Ozeki, Masafumi Kawamura, The Metastatic Lung Tumor Study Group of Japan
Characteristics of coronary microcirculatory function in patients with Takotsubo syndrome
Giuseppina Novo, Angelo Quagliana, Dario Buccheri, Salvatore Rizzo, Salvatore Giambanco, Francesco Giambanco, Salvatore Evola, Giovanna Geraci, Salvatore Novo
Reference values for spirometry in Chinese aged 4–80 years
Wenhua Jian, Yi Gao, Chuangli Hao, Ning Wang, Tao Ai, Chuanhe Liu, Yongjian Xu, Jian Kang, Lan Yang, Huahao Shen, Weijie Guan, Mei Jiang, Nanshan Zhong, Jinping Zheng
Elevated pretreatment serum lactate dehydrogenase level predicts inferior overall survival and disease-free survival after resection of thymic carcinoma
Qianwen Liu, Xiayu Fu, Xiaodong Su, Xin Wang, Yijun Zhang, Hong Yang, Yi Hu, Jing Wen, Jianhua Fu
Long-term outcomes of stage I NSCLC (≤3 cm) patients following segmentectomy are equivalent to lobectomy under analogous extent of lymph node removal: a PSM based analysis
Xiao Qu, Kai Wang, Tiehong Zhang, Hongchang Shen, Wei Dong, Qi Liu, Jiajun Du
Coated expandable metal stents are effective irrespective of airway pathology
Cecilia Menna, Camilla Poggi, Mohsen Ibrahim, Antonio D’Andrilli, Anna Maria Ciccone, Giulio Maurizi, Francesco Cassiano, Alberto E. Baccarini, Domenico Massullo, Federico Venuta, Erino A. Rendina, Claudio Andreetti

Technical Note

Prevention of cardiac herniation and left artery descending obstruction in cases of extensive surgical pericardial window procedure
Anton Sabashnikov, Ferdinand Kuhn-Régnier, Mohamed Zeriouh, Yeong-Hoon Choi, Navid Madershahian, Thorsten Wahlers


Clinical consensus of emergency airway management
Feng Sun, Ya Wang, Shicheng Ma, Huadong Zhu, Xuezhong Yu, Jun Xu, on behalf of Chinese Collaboration Group for Emergency Airway Management
Chinese Guideline on allergen immunotherapy for allergic rhinitis
Yixiao Bao, Jianjun Chen, Lei Cheng, Yinshi Guo, Suling Hong, Weijia Kong, He Lai, Houyong Li, Huabin Li, Jing Li, Tianying Li, Xiaoping Lin, Shixi Liu, Zheng Liu, Hongfei Lou, Juan Meng, Qianhui Qiu, Kunling Shen, Wei Tang, Zezhang Tao, Chengshuo Wang, Xiangdong Wang, Qingyu Wei, Li Xiang, Hua Xie, Yu Xu, Gehua Zhang, Yuan Zhang, Yiwu Zheng, Yuxiang Zhi, Dehua Chen, Haiyu Hong, Quansheng Li, Lin Liu, Yifan Meng, Nan Wang, Yihui Wang, Yue Zhou, Luo Zhang, Chinese Society of Allergy (CSA), Chinese Allergic Rhinitis Collaborative Research Group (C2AR2G)

Original Article of Interventional Pulmonology Corner1

Airway stent complications: the role of follow-up bronchoscopy as a surveillance method
Hans J. Lee, Wassim Labaki, Diana H. Yu, Benjamin Salwen, Christopher Gilbert, Andrea L. C. Schneider, Ricardo Ortiz, David Feller-Kopman, Sixto Arias, Lonny Yarmus

Review Article of Interventional Pulmonology Corner1

Persistent air leaks: a review with an emphasis on bronchoscopic management
Donald R. Lazarus, Roberto F. Casal

Original Article on Quantitative Imaging of Thoracic Diseases4

Texture analysis of CT imaging for assessment of esophageal squamous cancer aggressiveness
Song Liu, Huanhuan Zheng, Xia Pan, Ling Chen, Minke Shi, Yue Guan, Yun Ge, Jian He, Zhengyang Zhou
Combined CT angiography of the aorta and craniocervical artery: a new imaging protocol for assessment of acute type A aortic dissection
Didi Wen, Hongliang Zhao, Weixun Duan, Rui An, Jian Li, Minwen Zheng
The impact of chemotherapy on persistent ground-glass nodules in patients with lung adenocarcinoma
Wenwen Lu, Matthew D. Cham, Linlin Qi, Jianwei Wang, Wei Tang, Xiaolu Li, Jie Zhang
Logistic regression analysis and a risk prediction model of pneumothorax after CT-guided needle biopsy
Yanfeng Zhao, Xiaoyi Wang, Yong Wang, Zheng Zhu
Preliminary study on the diagnostic value of single-source dual-energy CT in diagnosing cervical lymph node metastasis of thyroid carcinoma
Yanfeng Zhao, Xiaolu Li, Lin Li, Xiaoyi Wang, Meng Lin, Xinming Zhao, Dehong Luo, Jianying Li
Ultrasound-guided percutaneous microwave ablation for benign breast lesions: evaluated by contrast-enhanced ultrasound combined with magnetic resonance imaging
Wei Zhang, Jian-Min Li, Wen He, Xiao-Ming Pan, Zhan-Qiang Jin, Ting Liang, Hui Zhang
Comparison of sonographic characteristics of primary thyroid lymphoma and anaplastic thyroid carcinoma
Li-Shuang Gu, Ning-Yi Cui, Yong Wang, Shu-Nan Che, Shuang-Mei Zou, Wen He, Jun-Ying Liu, Xuan-Tong Gong
CT findings of pulmonary nocardiosis: a report of 9 cases
Baoliang Liu, Yuanlong Zhang, Jingshan Gong, Shubing Jiang, Yunkai Huang, Lingwei Wang, Jianmin Xu, Chen Qiu
Evaluation of supplementary diagnostic value of contrast-enhanced ultrasound for lymph node puncture biopsy
Jie Zhang, Xin Hao, Yang Yang, Chang-Shuai Yan, Chao Ma, Ming Xiao, Li-Shuang Gu, Yong Wang

Case Report

Complete thoracoscopic excision of an infected bronchogenic cyst due to mediastinitis
Yong Hwan Kim, Jae Jun Kim, Si Young Choi, Seong Cheol Jeong, In Sub Kim
A laceration of left internal mammary artery caused by an amateur golfer’s swing
Deog-Gon Cho, Yong-Jin Chang, Kyu-Do Cho
Crizotinib plus radiotherapy in brain oligoprogressive NSCLC ROS1 rearranged and PD-L1 strong
Mario Occhipinti, Rosa Falcone, Concetta Elisa Onesti, Andrea Botticelli, Federica Mazzuca, Paolo Marchetti, Salvatore Lauro
Robot-assisted Ivor-Lewis esophagectomy with intrathoracic robot-sewn anastomosis
Runsen Jin, Jie Xiang, Dingpei Han, Yajie Zhang, Hecheng Li
Disseminated intravascular coagulopathy caused by type II endoleak after endovascular aneurysm repair in severe aortic stenosis
Jeong Seob Yoon, Jong Hui Suh, Do Yeon Kim, Chan Beom Park
Completion pneumonectomy after fenestration for empyema due to nontuberculous mycobacteriosis associated with destroyed lung as a result of cancer surgery
Ryo Takahashi, Taiki Fujiwara, Hisami Yamakawa
Use of veno-arterial extracorporeal membrane oxygenation in a case of tracheal injury repair in a patient with severe relapsing polychondritis
Anne-Sophie Laliberte, Christine McDonald, Tom Waddell, Kazuhiro Yasufuku
Dysphagia in the aging cardiovascular patient
Nicolas J. Mouawad, Guneet S. Ahluwalia
One-stage surgery in combination with thoracic endovascular grafting and resection of T4 lung cancer invading the thoracic aorta and spine
Seijiro Sato, Tatsuya Goto, Terumoto Koike, Takeshi Okamoto, Hirokazu Shoji, Masayuki Ohashi, Kei Watanabe, Masanori Tsuchida
Pulmonary inflammatory myofibroblastic tumor with TPM4-ALK translocation
Katsuhiro Okuda, Takuya Watanabe, Risa Oda, Tadashi Sakane, Osamu Kawano, Hiroshi Haneda, Satoru Moriyama, Ryoichi Nakanishi
Video-assisted thoracoscopic surgery right upper lobectomy in a situs inversus totalis patient
Minhua Ye, Jianfei Shen, Min Kong, Jiang Lin, Xiaodong Li, Baofu Chen
Routine aortic valve replacement followed by a myriad of complications: role of 3D printing in a difficult cardiac surgical case
Kálmán Benke, János Imre Barabás, László Daróczi, Alex Ali Sayour, Bálint Szilveszter, Miklós Pólos, Árpád Lux, Andrea Székely, Tamás Radovits, István Hartyánszky, Béla Merkely, Zoltán Szabolcs

Preface on Quantitative Imaging of Thoracic Diseases

Preface to 2017 focused issue: Quantitative Imaging of Thoracic Diseases
Yì Xiáng J. Wáng, Jiang Lin


1. The series “Interventional Pulmonology Corner” was commissioned by the Editorial office, Journal of Thoracic Disease without any sponsorship or funding. Kassem Harris served as the unpaid Guest Editor for the series.

2. The series “ECG Pearls” was commissioned by the Editorial office, Journal of Thoracic Disease without any sponsorship or funding. Adrian Baranchuk served as the unpaid Guest Editor for the series.

3. The series “GARD Section” was commissioned by the Editorial office, Journal of Thoracic Disease without any sponsorship or funding. Yousser Mohammad and Alvaro A. Cruz served as the unpaid Guest Editors for the series.

4. The series “Quantitative Imaging of Thoracic Diseases” was commissioned by the Editorial office, Journal of Thoracic Disease without any sponsorship or funding. Yì Xiáng J. Wáng and Jiang Lin served as the unpaid Guest Editors for the series.