Editorial Commentary


The tidal volume fix?

David J. Dries, John J. Marini

Abstract

Prior to publication of the ARDSNet trial of tidal volumes (VT) (1), traditional mechanical ventilation often employed VT of 10–15 mL/kg of unadjusted body weight. While these volumes had long been noted to exceed those of healthy subjects [who usually breathe at 6–8 mL/kg of predicted body weight (PBW)], they were considered necessary for intubated and mechanically ventilated patients to prevent progressive atelectasis, avoid dyspnea and maintain appropriate ventilation.

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