Chemotherapy induced changes to fibrin clots properties in lung cancer: is it favorable?

Patients with cancer are frequently in a hypercoagulable state and the reported incidences of venous thromboembolism (VTE) and arterial thrombosis in patients with cancer are 4–20% and 2–5%, respectively (1-3). In particular, VTE is associated with worse prognosis in patients with cancer (4,5); therefore, extensive investigations have been performed for the development of useful risk assessment models, identification of better VTE biomarkers, and exploration of efficient therapeutic interventions.