Rabies after lung transplantation: Existed evidence
Letter to the Editor
Rabies after lung transplantation: Existed evidence
Sir, rabies is a non-curable viral infection of the central nervous system. It is transmitted by animal bite. However, the uncommon mode of rabies transmission, transplantation transmission is possible (1). The consideration on lung transplantation should be mentioned. From simple literature searching, there are at least 3 reports on 4 rabid lung recipients from several non-tropical countries after lung transplantation (2-4). Common source from infectious donor was also reported (3). Of interest, there was no pre-transplantation screening of rabies. Also, no signs and symptoms of rabies could be seen in problematic donor. Since lung transplantation practice is the new therapeutic approach that is increasingly performed around the world, the concern on risk of infectious transplantation is needed. The risk of rabies should be kept in mind. As noted, the rabies transmission can be seen in nontropical countries, which are not the actual endemic area of rabies. Donor screening for rabies before transplantation might be needed.
Disclosure: The authors declare no conflict of interest.
Somsri Wiwanitkit, Viroj Wiwanitkit
Email: somsriwiwan@hotmail.com
DOI: 10.3978/j.issn.2072-1439.2012.05.01
  • Razonable RR. Rare, unusual, and less common virus infections after organ transplantation. Curr Opin Organ Transplant 2011;16:580-7.
  • Wohlsein P, Baumgärtner W, Kreipe HH, et al. [Rabies transmission through organ transplantation]. Pathologe 2011;32:406-10.
  • Maier T, Schwarting A, Mauer D, et al. Management and outcomes after multiple corneal and solid organ transplantations from a donor infected with rabies virus. Clin Infect Dis 2010;50:1112-9.
  • Mattner F, Henke-Gendo C, Martens A, et al. Risk of rabies infection and adverse effects of postexposure prophylaxis in healthcare workers and other patient contacts exposed to a rabies virus-infected lung transplant recipient. Infect Control Hosp Epidemiol 2007;28:513-8.
Cite this article as: Wiwanitkit S, Wiwanitkit V. Rabies after lung transplantation: Existed evidence. J Thorac Dis 2012;4(3):339-340. doi: 10.3978/j.issn.2072-1439.2012.05.01

Download Citation