Vol 17, No 11 (November 30, 2025): Journal of Thoracic Disease

Editorial Commentary

Subcutaneous administration of pembrolizumab: a paradigm shift toward patient-centered cancer care
Nobuaki Kobayashi
Journal of Thoracic Disease  
2025;
17
(11)
:9242-9246
.
Management of advanced non-small cell lung cancer with MET-exon-14-skipping alterations: challenges remain after the Chrysalis study
Christos Chouaïd, Jean-Baptiste Assié, Jean-Bernard Auliac
Journal of Thoracic Disease  
2025;
17
(11)
:9247-9250
.
Low dose CT for lung cancer screening
Philippe A. Grenier
Journal of Thoracic Disease  
2025;
17
(11)
:9251-9256
.
Active surveillance for clinical complete response after neoadjuvant treatment of locally advanced esophageal cancer
Jens Hoeppner, Fabian Nimczewski
Journal of Thoracic Disease  
2025;
17
(11)
:9257-9259
.
Immune checkpoint inhibitors for advanced non-small cell lung cancer with poor performance status or older patients
Naoki Furuya
Journal of Thoracic Disease  
2025;
17
(11)
:9260-9262
.
Immune checkpoint inhibitor resistance in non-small cell lung cancer: limits of vascular endothelial growth factor inhibition and new directions
Hiroyasu Kaneda
Journal of Thoracic Disease  
2025;
17
(11)
:9263-9270
.
Avoiding the toll of lung injury while driving CAR T cells to the target tumor
Victoria Cranwell, Prasad S. Adusumilli, Meriem Taleb
Journal of Thoracic Disease  
2025;
17
(11)
:9271-9274
.

Original Article

Prone positioning in cone beam CT-guided robotic bronchoscopy case series: a strategy to minimize atelectasis and improve access to posteromedial lower lobe nodules
Abdul Hamid Alraiyes, Clayton Johnson, Nikolina Madjer, Christopher Bentsen, Noah Gordon, Ronak S. Patel, Mae Leef, Danielle Gratza, Daniel Sherlock, Fayez Kheir
Journal of Thoracic Disease  
2025;
17
(11)
:9275-9286
.
Resveratrol restores glucocorticoid receptor and HDAC2 to overcome corticosteroid resistance in cigarette smoke-induced emphysema mice
Zengyu Huo, Xiaoli Chen, Guixian Zheng, Xinyan Wei, Yanbing Huang, Jiawei Zou, Siyi Ou, Cunlai Xu, Yang Yang, Siming Chen, Jing Bai
Journal of Thoracic Disease  
2025;
17
(11)
:9287-9299
.
Effective determination of pre-chronic obstructive pulmonary disease by symptoms and CT features: a multicenter cross-sectional study
Rong You, Chu Qin, Min Lu, Lirong Huang, Weijuan Xu, Lu Liu, Yanting Liu, Jintao Dai, Jie Wang, Yu Ding, Yuanyuan Wang, Haixia Mao, Yu Zhang, Haoda Yu, Tao Bian
Journal of Thoracic Disease  
2025;
17
(11)
:9300-9313
.
Prediction of EGFR mutation status and mutation sites in lung cancer based on radiomics and deep learning
Zheng Zeng, Rui Zhang, Yucai Dong, Baocong Liu, Huiyun Ma, Yuquan Zheng, Xin Gao, Qiong Li
Journal of Thoracic Disease  
2025;
17
(11)
:9314-9328
.
Association between underdiagnosed and overdiagnosed chronic obstructive pulmonary disease with all-cause mortality
Suyin Huang, Juncheng Liang, Zhishan Deng, Qi Wan, Kunning Zhou, Fan Wu, Yumin Zhou
Journal of Thoracic Disease  
2025;
17
(11)
:9329-9341
.
Risk factors and perioperative complications associated with deep venous thrombosis and pulmonary embolism after lung transplantation
Nathan T. Kim, Yudai Miyashita, Taisuke Kaihou, Joshua T. Kim, Chitaru Kurihara
Journal of Thoracic Disease  
2025;
17
(11)
:9342-9356
.
Urinothorax and pleural fluid creatinine: a retrospective analysis of pleural fluid studies at a tertiary care center and a review of the literature
Kevin E. Shayani, Jacob Schwartz, Nicole Oslance, Brandon Wilson, Oki Ishikawa, Omar Mahmoud, Viera Lakticova
Journal of Thoracic Disease  
2025;
17
(11)
:9357-9363
.
Influence of neoadjuvant immunotherapy on surgical approaches in non-small cell lung cancer: insights from a Chinese Expert Questionnaire Survey on Contemporary Practices
Han Wu, Long Jiang, Jiantao Li, Jia Huang, Yunhai Yang, Qingquan Luo, Tianxiang Chen
Journal of Thoracic Disease  
2025;
17
(11)
:9364-9374
.
Long-term clinical outcomes of mediastinal lymphoma after surgical resection: reassessing the role of surgery
Sangil Yun, Chang Hyun Kang, Tae Min Kim, Taeyoung Yun, Ji Hyeon Park, Bubse Na, Kwon Joong Na, Samina Park, Hyun Joo Lee, In Kyu Park, Young Tae Kim
Journal of Thoracic Disease  
2025;
17
(11)
:9375-9387
.
Epidemiological burden and mortality of idiopathic pulmonary fibrosis in Brazil: historical trends and future outlook
Rogerio Rufino, Lucas Resende Martinez Araujo, Leonardo Palermo, Elizabeth Bessa, Bruno Rangel, Mariana Lopes, Mariana Costa Rufino, Anamelia Costa Faria, Claudia Henrique da Costa
Journal of Thoracic Disease  
2025;
17
(11)
:9388-9396
.
CT-based emphysema score is associated with prolonged air leak after lung resection: a retrospective cohort study
Wara Naeem, Arsalan A. Khan, Minha Ansari, Oluwamuyiwa W. Adebayo, Sanjib Basu, Gillian Alex, Nicole Geissen, Michael J. Liptay, Christopher W. Seder
Journal of Thoracic Disease  
2025;
17
(11)
:9397-9410
.
Development and validation of a multi-center prognostic model for predicting survival in non-small cell lung cancer using pulmonary and hematological data
Peihong Hu, Hang Gu, Zitao Tang, Wen Li, Xiaoqin Liu, Qiang Li, Run Xiang
Journal of Thoracic Disease  
2025;
17
(11)
:9411-9424
.
Efficacy and safety of mepolizumab in severe eosinophilic asthma: a systematic review and meta-analysis
Yubing Li, Jun Li, Hongxia Yang, Linguo Wu
Journal of Thoracic Disease  
2025;
17
(11)
:9425-9438
.
Survey of physicians’ approaches to the clinical evaluation of interstitial lung disease in Singapore (SoPhoCLES)
Felicia S. W. Teo, Gin Tsen Chai, Su Ying Low, Tunn Ren Tay, Simon L. F. Walsh, Maria Kokosi, Masashi Takahashi, Vincent Cottin, Wim A. Wuyts, Felix Chua, Pyng Lee, Lynette L. S. Teo, Gregory Kaw, Yuen Li Ng, Liang Shen, Chia Meng Teoh, Jin Woo Song
Journal of Thoracic Disease  
2025;
17
(11)
:9439-9450
.
Validation of cough evaluation test in subacute cough
Jianyi Li, Yuling Li, Wenzhi Zhan, Xiaomei Chen, Lianrong Huang, Fang Yi, Jiaxing Xie, Kefang Lai
Journal of Thoracic Disease  
2025;
17
(11)
:9451-9458
.
A retrospective study with whole-exome sequencing of tissue samples: analysis of risk factors in patients of persistent cough following lung segmentectomy
Xuefeng Sun, Zihua Lan, Shaopeng Li, Rixin Chen, Guibin Qiao
Journal of Thoracic Disease  
2025;
17
(11)
:9459-9469
.
Feasibility of extracting key elements from thoracic surgical operative notes using foundational large language models
Vamshi Mugu, Vera Sorin, Alex Chan, Casey Briggs, Brendan Carr, Mike Olson, John Schupbach, John Zietlow, Sahar Saddoughi, John Schmitz, Ashish Khandelwal
Journal of Thoracic Disease  
2025;
17
(11)
:9470-9477
.
Correlation between albumin-corrected calcium levels and prognosis in non-ST-elevation myocardial infarction patients: a retrospective cohort study using the MIMIC-IV database
Chenghao Wang, Yinqin Hu, Junxiong Li, Jingwen Zhang, Shanghua Liang
Journal of Thoracic Disease  
2025;
17
(11)
:9478-9491
.
Associations of inflammatory burden index with the prevalence and mortality of asthma in adults: a population based study
Zhenfa Wang, Yongwei Fan, Zhenyun Tan, Ling Wang, Jiarui Zhang, Zhaoxi Wang, Guqin Zhang
Journal of Thoracic Disease  
2025;
17
(11)
:9492-9505
.
Incidence and risk factors of posttransplant diabetes mellitus in lung transplant recipients: a retrospective cohort study
Wenwen Li, Guolong Zhang, Ying Chen, Meiqi Lai, Xiuni Zheng, Kefan Wu, Bin Wang, Daqun Wu, Minting Kuang, Min Dong, Wenjuan Rong, Liang Ruan, Danxia Huang
Journal of Thoracic Disease  
2025;
17
(11)
:9506-9516
.
Pulmonary artery reconstruction using cryopreserved allograft for lung cancer: a bi-centric comparative study
Kheira Hireche, Tayeb Benkiran, Aude Nguyen, Sébastien Frey, Adeline Morisot, Laurence Solovei, Quentin Rudondy, Jean-Philippe Berthet
Journal of Thoracic Disease  
2025;
17
(11)
:9517-9527
.
The continued importance of surgical resection in the management of pulmonary neuroendocrine tumours
Urim Starova, Dominik Herrmann, Melanie Oggiano, Thorsten Walles, Erich Hecker
Journal of Thoracic Disease  
2025;
17
(11)
:9528-9536
.
Diagnostic value of pleural fluid carbohydrate antigen 242 for malignant pleural effusion
Xi Lin, Yan Niu, Jian-Xun Wen, Mei Li, Wen-Qi Zheng, Li Yan, Ran-Tong Bao, Zhi-De Hu, Man Zhang, Ya-Nan Xu
Journal of Thoracic Disease  
2025;
17
(11)
:9537-9544
.
Association of Life’s Crucial 9 with asthma in U.S. adults: a cross-sectional study from National Health and Nutrition Examination Survey (NHANES)
Kang Wang, Lijun He, Jin Wei, Liang Gong, Zhujun Chen
Journal of Thoracic Disease  
2025;
17
(11)
:9545-9556
.
A retrospective evaluation of risk factors for an inadequate surgical margin in preoperative lipiodol marking for small-sized pulmonary lesions
Sho Takeda, Satoshi Fumimoto, Shohei Okai, Yuki Shindo, Katsushi Toyohara, Kiyoshi Sato, Nobuharu Hanaoka, Takahiro Katsumata
Journal of Thoracic Disease  
2025;
17
(11)
:9557-9567
.
Global trends and hotspots in research of cough variant asthma: a bibliometric and visual analysis from 2004 to 2024
Hai-Yang Yu, Yi-Fei Fan, Fang Du
Journal of Thoracic Disease  
2025;
17
(11)
:9568-9585
.
Involvement of mitochondrial unfolded protein response and activating transcription factor 4 in the mitochondrial damage pathway of BEAS-2B cells induced by cigarette smoke extracts
Jie Jin, Tiantian Cen, Minxuan Huang, Feng Xu, Qunli Ding, Dan Lv, Shanshan Wang, Lin Fei, Hongying Ma, Panfeng Fu
Journal of Thoracic Disease  
2025;
17
(11)
:9586-9597
.
Hydrogen rescues vascular endothelial cells in obstructive sleep apnea-hypopnea syndrome by modulating nitric oxide
Qi Chen, Dandan Jiang, Jie He, Mili Sun
Journal of Thoracic Disease  
2025;
17
(11)
:9598-9609
.
Non-contact artificial intelligence-assisted intraoperative 3D navigation technology prospective application study in lung cancer surgery
Chengrun Li, Jiachun Song, Rui Yan, Bo Zhang, Bin Wang, Jingfan Fan, Yifei Yang, Hongxu Yue, Jixing Lin, Ruiji Chen, Leilei Shen, Hengliang Xu, Shurui Wu, Zhengnan Liu, Jie Li
Journal of Thoracic Disease  
2025;
17
(11)
:9610-9621
.
Development of machine learning-based prognostic models for small cell lung cancer with brain metastases: an analysis of SEER and Chinese populations
Mingyuan Guo, Jun Zhu, Xiaoman Duan, Pengyue Ren, Haitao Wang, Yu Zhang, Hailing Lu, Yanbin Zhao
Journal of Thoracic Disease  
2025;
17
(11)
:9622-9641
.
Development of a nomogram to predict 30-day mortality in patients with chronic obstructive pulmonary disease complicated by sepsis: insights from the Medical Information Mart for Intensive Care (MIMIC-IV) database
Jingjing Yin, Ruiqiang Zheng, Jiangquan Yu, Xianghui Li, Xiaoyan Wu
Journal of Thoracic Disease  
2025;
17
(11)
:9642-9654
.
Association of forced expiratory volume in 0.5 seconds/forced vital capacity ratio with all-cause mortality in adults: a cohort study
Ranxi Peng, Juncheng Liang, Fan Wu, Jie Ou, Shiyu Zhang, Leheng Tang, Qiaorui Zhou, Siman Liao, Yingtong Chen, Xiaozi Guo, Jingxian Chen, Qi Wan, Zihui Wang, Zhishan Deng, Yumin Zhou
Journal of Thoracic Disease  
2025;
17
(11)
:9655-9669
.
The role of targetable biomarker alterations in overall survival for non-small cell lung cancer (NSCLC) in a large integrated health system
Alberto Jarrin Lopez, Lori C. Sakoda, Haley I. Tupper, Jingrong Yang, William P. Carroway, Kenneth Williams, Jennifer Marie Suga, Meera Ragavan, Jeffrey B. Velotta
Journal of Thoracic Disease  
2025;
17
(11)
:9670-9679
.
Serum electrolytes as prognostic markers: a new frontier in acute exacerbation of chronic obstructive pulmonary disease (AECOPD) management
Shuting Chang, Mingming Chen, Yunpeng Xu, Donglun Li, Xue Han, Qiuyu Chen, Jian Liu
Journal of Thoracic Disease  
2025;
17
(11)
:9680-9695
.
Lung-protective effects of esketamine in patients undergoing video-assisted thoracoscopic surgery: a randomized controlled trial
Fei Yang, Tong Mu, Wanling Xiong, Xia Yin, Wei Ran, Ruixue Yuan, Ning Liang, Jin Gao
Journal of Thoracic Disease  
2025;
17
(11)
:9696-9710
.
Interleukin-6-to-lymphocyte count ratio in the prognosis of moderate-to-severe acute respiratory distress syndrome supported by venovenous extracorporeal membrane oxygenation: a single-center retrospective study
Xiaojiao Tan, Lin Han, Jing Pang, Shulin Xiang, Bin Xiong
Journal of Thoracic Disease  
2025;
17
(11)
:9711-9720
.
Development and validation of a multimodal radiomics-serum biomarker model for diagnosing solid pulmonary nodules via machine learning
Kai Wang, Xu-Feng Deng, Zhi Zheng, Zi-Qi Huang, Shuang-Qing Liao, Si-Jin Liu, Zhuo-Xin Dai, Ji-Gang Dai, Quan-Xing Liu
Journal of Thoracic Disease  
2025;
17
(11)
:9721-9734
.
Is induction therapy optimal for all patients with locally advanced distal esophagus adenocarcinoma?—The impact of age and co-morbidities on treatment and outcomes
Mark F. Berry, Chris Aboujudom, Michelle Chan, Douglas Z. Liou
Journal of Thoracic Disease  
2025;
17
(11)
:9735-9750
.
Risk factors in psychological resilience of patients receiving chemotherapy for lung cancer
Yi Zhao, Xuejiao Leng, Ruo Du, Zhiwei Chen
Journal of Thoracic Disease  
2025;
17
(11)
:9751-9762
.
Comparison of short-term outcomes between non-intubated and intubated video-assisted thoracoscopic surgery: a propensity score matching analysis
Weixiang Lu, Hongsheng Deng, Qing Ai, Ze Wang, Jianxing He, Wenlong Shao, Long Jiang
Journal of Thoracic Disease  
2025;
17
(11)
:9763-9773
.
Preoperative pulmonary function and nutrition predict survival in lung cancer patients with previous operated malignancies
Hiromichi Niikawa, Hirotsugu Notsuda, Ken Onodera, Tatsuaki Watanabe, Yui Watanabe, Takashi Hirama, Takeo Togo, Sakiko Kumata, Takaya Suzuki, Hisashi Oishi, Masafumi Noda, Yoshinori Okada
Journal of Thoracic Disease  
2025;
17
(11)
:9774-9788
.
Predictive factors for late recurrence beyond 5 years after curative resection of stage I non-small cell lung cancer: a risk scoring approach
Masaya Tamura, Naoki Furukawa, Yujiro Bunno, Marino Yamamoto, Ryohei Miyazaki, Hironobu Okada
Journal of Thoracic Disease  
2025;
17
(11)
:9789-9798
.
SCM-198 ameliorates pulmonary arterial hypertension by modulating gut microbiota in rats
Jianyu Xiong, Qinyang Ge, Bohan Fu, Jiayao Li, Zhongxiao Lin, Yi Zhun Zhu
Journal of Thoracic Disease  
2025;
17
(11)
:9799-9812
.
Clinical characteristics and prognostic analysis of 22 cases of SMARCA4-deficient thoracic tumors: a retrospective observational study
Xuemin Yang, Mingming Wang, Feng Jin, Xin Fu, Lu Wang, Liqiang Song, Wenrui Jiang
Journal of Thoracic Disease  
2025;
17
(11)
:9813-9826
.
Bronchiectasis complicated by pulmonary aspergillosis: a multicenter study on prognosis and risk factors
Jie Yang, Xinyu Wang, Shuai Lu, Kui Zhang, Xin Su
Journal of Thoracic Disease  
2025;
17
(11)
:9827-9835
.
Preoperative C-reactive protein-augmented CONUT score as a better prognostic indicator than CONUT alone in non-small cell lung cancer across age groups
Takashi Sakai, Masaya Tamura, Naoki Furukawa, Yujiro Bunno, Marino Yamamoto, Ryohei Miyazaki, Hironobu Okada
Journal of Thoracic Disease  
2025;
17
(11)
:9836-9846
.
Electronic patient-reported outcomes for outpatient care after non-intubated thoracic surgery in early-stage lung cancer
Shiqin Xie, Meihua Li, Run Li, Ying Chen, Wenwei Guo, Danxia Huang
Journal of Thoracic Disease  
2025;
17
(11)
:9847-9855
.
Comparison of uniportal and three-portal video-assisted thoracoscopic thymectomy for thymoma: a propensity score-matched study
Zipu Yu, Guofei Zhang, Gang Shen
Journal of Thoracic Disease  
2025;
17
(11)
:9856-9863
.
Evaluating the role of American Thoracic Society/European Respiratory Society/Japanese Respiratory Society/Latin American Thoracic Society high-resolution CT-thorax usual interstitial pneumonitis imaging categories in selecting candidates for transbronchial lung cryobiopsy for undifferentiated interstitial lung disease, a retrospective study
Sean Landers, Juliette M. Morrow, Grace O’Sullivan, Louise Burke, Deirdre Doyle, Michael M. Maher, Michael T. Henry
Journal of Thoracic Disease  
2025;
17
(11)
:9864-9873
.
Fractional exhaled nitric oxide (FeNO) in chronic obstructive respiratory diseases is associated with the bronchodilator response
Thuy Chau Nguyen, Hoa Vi Thi Tran, Thanh Hiep Nguyen, Mong Hiep Thi Tran, Isabelle Godin, Olivier Michel
Journal of Thoracic Disease  
2025;
17
(11)
:9874-9884
.
Evaluating non-contrast 3D reconstructions for pulmonary segmentectomy: a reliable alternative to contrast-enhanced models in thoracic surgery
Chloé Lafouasse, Rime Essid, Guillaume Boddaert, Agathe Seguin-Givelet
Journal of Thoracic Disease  
2025;
17
(11)
:9885-9894
.
Dynamic Modified Early Warning Score for predicting postoperative mortality in acute type A aortic dissection: a retrospective study
Xiluan Li, Yongquan Zhang, Yequn Chen, Zhili Liu, Yanchun Wu, Manshan Sun, Hong Zhang
Journal of Thoracic Disease  
2025;
17
(11)
:9895-9903
.
Predictors of forced vital capacity response to immunosuppression in fibrotic hypersensitivity pneumonitis: a retrospective cohort analysis of 203 patients
Tananchai Petnak, Teng Moua
Journal of Thoracic Disease  
2025;
17
(11)
:9904-9914
.
Pemetrexed plus platinum outperforms other platinum-based adjuvant chemotherapy regimens for resected stage II–IIIA lung adenocarcinoma: an open-label, historical-control study
Xumeng Ji, Qiwen Zheng, Bo Jia, Lingdong Kong, Yuling He, Xiaoyu Zhai, Tongtong An, Jianjie Li, Yuyan Wang, Yujia Chi, Jingjing Wang, Lu Ding, Yidi Tai, Reyizha Nuersulitan, Xingsheng Hu, Fan Yang, Ziping Wang
Journal of Thoracic Disease  
2025;
17
(11)
:9915-9926
.
Single-cell and spatial transcriptome landscapes reveal the spatial immune defense pattern shared by primary and brain metastatic lung adenocarcinoma
Fanchen Meng, Yuxiang Sun, Jianyu Li, Lin Xu
Journal of Thoracic Disease  
2025;
17
(11)
:9927-9942
.
Global trends in the burden of tracheal, bronchus, and lung cancer attributable to household air pollution
Shen Lao, Jianfu Li, Wangzhong Li, Hengrui Liang, Wenhua Liang, Fuli Li, Wei Wang
Journal of Thoracic Disease  
2025;
17
(11)
:9943-9957
.
Comparison of thoracic epidural anesthesia with an erector spinae plane infusion for post-esophagectomy analgesia: a pragmatic retrospective cohort study
Robert J. McCarthy, Denis Snegovskikh, Daniel Torrez, Kathryn L. Schmitt, Zoë E. Bilello, Asokumar Buvanendran
Journal of Thoracic Disease  
2025;
17
(11)
:9958-9968
.
Body mass index, ventilator parameters, and mortality in acute respiratory distress syndrome: re-examining the obesity paradox
Tae Wan Kim, Hyo Suk Oh, Ji Hyun Cha, Miryo Nam, Gee Young Suh, Chi Ryang Chung, Ryoung-Eun Ko
Journal of Thoracic Disease  
2025;
17
(11)
:9969-9979
.
Association between early-life respiratory syncytial virus infection and the risk of asthma: a meta-analysis
Xi-Qun Jia, Liang Lu, Shi-Yang Lou, Si-Yu Han, Lin-Li Deng, Wei-Sheng Wu, Shu-Hua Liu
Journal of Thoracic Disease  
2025;
17
(11)
:9980-9996
.
Effect of cardiovascular risk factors on overall survival in postoperative patients with esophageal squamous cell carcinoma: a retrospective cohort analysis
Yang Zhang, Sen Chen, Jia-Xing Ke, Nan Lu, Xue-Ping Zhang, Hai-Feng Chen
Journal of Thoracic Disease  
2025;
17
(11)
:9997-10009
.
Impact of prognostic nutritional index on postoperative outcome of acute empyema
Toshio Shiotani, Noriaki Shiraha, Kaoru Kondo, Shinichi Furukawa, Mototsugu Watanabe
Journal of Thoracic Disease  
2025;
17
(11)
:10010-10022
.
Vaping nicotine is associated with increased medically-attended COVID-19 in women of reproductive age in an integrated health system
Jeffrey B. Velotta, Ilya Moskalenko, Shiyun Zhu, Sara R. Adams, Joshua R. Nugent, Tyler Chervo, Jacek Skarbinski, Judith J. Prochaska, Qiana L. Brown, Cynthia I. Campbell, Aurash J. Soroosh, Monique B. Does, Kelly C. Young-Wolff
Journal of Thoracic Disease  
2025;
17
(11)
:10023-10035
.
Comparison of metagenomic next-generation sequencing (mNGS) technology with routine laboratory culture for bacterial and fungal detection in bronchoalveolar lavage fluid
Yang Liu, Nan Deng, Yuting Lu, Jiayi Peng, Siqi Yuan
Journal of Thoracic Disease  
2025;
17
(11)
:10036-10044
.
The prevalence of chronic obstructive pulmonary disease in high-altitude areas of China: a systematic review and meta-analysis
Shuna Wei, Xiaoju Liu
Journal of Thoracic Disease  
2025;
17
(11)
:10045-10057
.
Global research trends in influenza-associated acute lung injury/acute respiratory distress syndrome: a bibliometric analysis from 2010 to 2024
Jiajie Li, Jinxing Liu, Ze Zhou, Yaping Wang, Cheng Luo, Huantian Cui, Qin Li, Weibo Wen
Journal of Thoracic Disease  
2025;
17
(11)
:10058-10076
.
Association between hemoglobin-to-red cell distribution width ratio and 30-day mortality after cardiac surgery
Xian-Dong Wang, Xu Liu, Xiong-Fei Xia, Yang Lan, Yun-Yun Wang, Xin-Yue Yang, Zhi-Yong Quan, Dai Li, Jia-Feng Wang, Jin-Jun Bian
Journal of Thoracic Disease  
2025;
17
(11)
:10077-10088
.
Maintaining lung volume in a chest wall deformity after chest wall reconstruction
Shogo Mitamura, Akio Sakamoto, Kazuhiro Murotani, Takashi Noguchi, Shuichi Matsuda
Journal of Thoracic Disease  
2025;
17
(11)
:10089-10097
.
Endovascular treatment outcomes for descending thoracic aortic pathologies in octogenarians: retrospective study
Emad M. AL-Osail, Alizee Porto, Mariangela De Masi, Virgile Omnes, Alexis Jacquier, Philippe Piquet, Marine Gaudry
Journal of Thoracic Disease  
2025;
17
(11)
:10098-10105
.
Rate of early restenosis after tracheal resection in patients post-COVID-19 infection: a multicenter real-life study
Giuseppe Mangiameli, Debora Brascia, Beatrice Trabalza Marinucci, Umberto Cariboni, Giulio Maurizi, Diana Bacchin, Marco Lucchi, Marco Mammana, Federico Rea, Giuseppe Marulli, Erino Angelo Rendina
Journal of Thoracic Disease  
2025;
17
(11)
:10106-10117
.
Evaluation of Progel in minimally invasive segmentectomy: a multicentric retrospective series
Giulia Fabbri, Nabih Berjaoui, Akshay Patel, Alessandro Maraschi, Savvas Lampridis, Ilies Bouabdallah, Andrea Bille
Journal of Thoracic Disease  
2025;
17
(11)
:10118-10126
.
Performance evaluation of deep learning-based osteoporosis diagnostic models with conventional chest X-ray in a clinical cohort
Bona Koo, Yelin Roh, Gyubin Shin, Yujin Yang, Rena Lee, Sungho Cho, So Hyun Ahn, Kwan-Chang Kim
Journal of Thoracic Disease  
2025;
17
(11)
:10127-10137
.
The effect of lobar versus sublobar video-assisted thoracoscopic surgery lung resection on patient quality of life
Lyndon C. Walsh, Joseph Seitlinger, Morgan S. Gold, Mark Sorin, Francesca Fermi, James Tankel, Merav Rokah, Roni Rayes, David Mulder, Christian Sirois, Jonathan Cools-Lartigue, Sara Najmeh, Lorenzo Ferri, Julio F. Fiore Jr, Jonathan D. Spicer
Journal of Thoracic Disease  
2025;
17
(11)
:10138-10148
.
Hepatocyte growth factor alleviates alcoholic cardiomyopathy through the Nrf2 pathway—a focus on iron metabolism
Yichao Yu, Ji Chen, Kejiang Cao, Jian Zhang
Journal of Thoracic Disease  
2025;
17
(11)
:10149-10162
.
Feasibility of establishing a nude mouse model of thymoma-associated myasthenia gravis
Jun Zhang, Yijie Yan, Zhiyu Guan
Journal of Thoracic Disease  
2025;
17
(11)
:10163-10171
.
Intraprocedural O-arm computed tomography-guided navigation with ventilatory strategy for atelectasis electromagnetic navigation bronchoscopic biopsy of peripheral lung lesions: an IDEAL stage 2a study
Guoqiu Xu, Jian Tang, Shaohua Dai
Journal of Thoracic Disease  
2025;
17
(11)
:10172-10185
.
Non-intubated uniportal video-assisted thoracoscopic anatomical lung volume reduction surgery—an institutional report
Tomoyuki Nakagiri, Hayan Merhej, Alaa Selman, Akylbek Saipbaev, Tobias Goecke, Arjang Ruhparwar, Patrick Zardo
Journal of Thoracic Disease  
2025;
17
(11)
:10186-10194
.
Integrative use of conventional mode and elastography in endobronchial ultrasound for the diagnosis of malignant intrathoracic lymphadenopathy
Potjanee Korrungruang, Viboon Boonsarngsuk, Prapaporn Pornsuriyasak, Thammanard Charernboon
Journal of Thoracic Disease  
2025;
17
(11)
:10195-10208
.
Phase 2 feasibility study of adjuvant chemotherapy with cisplatin (CDDP) and TS-1, followed by alternate-day TS-1 maintenance therapy, in patients with completely resected pathological stage II-IIIA non-small cell lung cancer
Kosuke Fujino, Riichiroh Maruyama, Takashi Marutsuka, Kazunori Iwatani, Masaya Aoki, Takayuki Suetsugu, Masaru Takenaka, Sho Saeki, Shinya Sakata, Yamato Motooka, Yoshiko Masuda, Kentaro Yoshimoto, Koei Ikeda, Makoto Suzuki
Journal of Thoracic Disease  
2025;
17
(11)
:10209-10219
.
Pressure record analysis method parameters during weaning success and failure from mechanical ventilation in prolonged ventilated patients after cardiac surgery
Yuankai Zhou, Shengjun Liu, Liangyu Mi, Yingying Yang, Siyi Yuan, Huaiwu He, Yun Long
Journal of Thoracic Disease  
2025;
17
(11)
:10220-10229
.
Slow-firing mode reduces stump oozing during pulmonary vessel stapling
Takuya Kohama, Masayuki Tanahashi, Haruhiro Yukiue, Takeshi Yamada, Eriko Suzuki, Naoko Yoshii, Takuya Watanabe, Hiroyuki Tsuchida, Kosuke Shibata, Takumi Endo
Journal of Thoracic Disease  
2025;
17
(11)
:10230-10240
.
Modified free pericardial fat pledget technique for intraoperative air leak management in robotic-assisted thoracic surgery
Yoshiki Chiba, Masahiro Miyajima, Kazuya Honda, Kazuki Sato, Takeshi Ohyu, Yuki Takahashi, Ryunosuke Maki, Atsushi Watanabe
Journal of Thoracic Disease  
2025;
17
(11)
:10241-10253
.
Outcomes of minimally invasive lung resection with concomitant chest wall resection in non-small cell lung cancer (NSCLC)
Sneha S. Alaparthi, Anurag Ishwar, Isheeta Madeka, Annie Ho, Tyler Grenda, Nathaniel R. Evans III, Olugbenga T. Okusanya
Journal of Thoracic Disease  
2025;
17
(11)
:10254-10261
.
Enhanced recovery in lung surgery: coaxial versus conventional chest drains following video-assisted thoracoscopic surgery lobectomy—a prospective randomized trial
Mohamed Salama, Michael Rolf Mueller
Journal of Thoracic Disease  
2025;
17
(11)
:10262-10271
.
Association between stress hyperglycemia ratio and 28-day all-cause mortality in critically ill atrial fibrillation patients: a retrospective cohort study based on the MIMIC-IV database
Qianqian Zhang, Nianzhi Zhang, Jing Zhou, Ying Zheng, Yuanyuan Wang
Journal of Thoracic Disease  
2025;
17
(11)
:10272-10284
.
Risk factors and survival associated with lung cancer recurrence after curative-intent surgery: beyond TNM pathological staging
Brandon S. Hendriksen, Belisario A. Ortiz, Dennis A. Wigle, Stephen D. Cassivi, Sahar A. Saddoughi, Carlos A. Puig, K. Robert Shen, Janani S. Reisenauer, Luis F. Tapias
Journal of Thoracic Disease  
2025;
17
(11)
:10285-10297
.
Performance of metagenomic next-generation sequencing, Xpert MTB/RIF and acid-fast staining for diagnosing tuberculous pleurisy and empyema
Hong Liu, Saiguang Ji, Fuchen Xing, Chenyan Wang, Wei Sun, Hongan Shao, Chunmei Hu
Journal of Thoracic Disease  
2025;
17
(11)
:10298-10307
.
Effects of driving pressure-guided lung-protective ventilation strategy on respiratory mechanics, oxygenation, and postoperative pulmonary complications in patients undergoing minimally invasive esophagectomy: a randomized clinical trial
Lin Zhang, Zhengxia Sun, Jiaqi Chang, Yu Ma, Hui Liu, Qingming Bian
Journal of Thoracic Disease  
2025;
17
(11)
:10308-10323
.
Impact of preoperative left ventricular diastolic dysfunction on primary graft dysfunction and mortality following lung transplantation
Shixiao Tang, Xinyu Feng, Jieyu Hua, Mingyue Chen, Ke Wang, Shuai Miao, Jingjing Xu, Min Dai, Sijia Gu, Xiao Liang, Yiling Qian, Chunxiao Hu, Dongxiao Huang
Journal of Thoracic Disease  
2025;
17
(11)
:10324-10336
.
Outpatient opioid use after minimally invasive surgery for lung cancer: a Surveillance, Epidemiology, and End Results-Medicare cohort study
Alyssa Murillo, Gediwon Milky, Tessa Runels, I-Fan Shih, Daniel S. Oh, Johannes R. Kratz
Journal of Thoracic Disease  
2025;
17
(11)
:10337-10347
.
Delay in lung volume reduction surgery due to the COVID-19 pandemic: impact on patient performance and mortality
Alberte Lund, Henrik J. Hansen, Kåre Hornbech, Michael Perch, Anna Kalhauge, Jann Mortensen, Kristine Jensen, René H. Petersen
Journal of Thoracic Disease  
2025;
17
(11)
:10348-10355
.
Global trends and research hotspots in pulmonary rehabilitation for chronic obstructive pulmonary disease: a bibliometric analysis (2011–2024)
Qian Yuan, Zhu Zeng
Journal of Thoracic Disease  
2025;
17
(11)
:10356-10374
.
Contrast-enhanced computed tomography-based intratumoral and peritumoral radiomics for identifying malignancy in pulmonary ground-glass nodules
Zhiqiang Peng, Fei Xie, Xiaofei Tang, Qifu Liu, Lei Nie, Ailin Chen
Journal of Thoracic Disease  
2025;
17
(11)
:10375-10385
.
The evolution of airway stenting research: a bibliometric analysis of the 100 most influential articles
Jinjiang Li, Jiansheng Yin, Siyun Song
Journal of Thoracic Disease  
2025;
17
(11)
:10386-10406
.
Computed tomography-guided lipiodol marking enables margin-secure wedge resection for colorectal pulmonary metastases
Katsushi Toyohara, Satoshi Fumimoto, Nobuharu Hanaoka, Yuki Shindo, Kiyoshi Sato, Takahiro Katsumata
Journal of Thoracic Disease  
2025;
17
(11)
:10407-10416
.
A computed tomography-based deep learning radiomics for predicting the response to neoadjuvant chemotherapy combined with immunotherapy in patients with locally advanced esophageal cancer: a multicenter cohort study
Minhua Ye, Junjie Mao, Jiang Jin, Hao Liu, Haixie Guo, Yunrui Xu, Pengjie Yang, Liang Ma
Journal of Thoracic Disease  
2025;
17
(11)
:10417-10429
.
Proximal stent graft combined with distal bare stent vs. conventional thoracic endovascular aortic repair in the treatment of complicated Stanford type B aortic dissection: a systematic review and meta-analysis
Peng Lin, Shouji Qiu, Chengkai Hu, Yuchong Zhang, Enci Wang, Fandi Mo, Weiguo Fu, Lixin Wang
Journal of Thoracic Disease  
2025;
17
(11)
:10430-10444
.
Pseudomonas putida KT2440-induced RBM47 regulates non-small cell lung cancer stem cell properties and T cell-mediated antitumor activity
Qiu-Xiang Zheng, Bao-Ling Guo, Yun-Shan Jiang, Rong-Rong Zhong, Nagashree Seetharamu, Katsuhiro Okuda, Alessandro Inno, Ying Zhan, Wen-Jin Huang, Zhi-Yong Chen
Journal of Thoracic Disease  
2025;
17
(11)
:10445-10458
.
Molecular mechanism of obesity-related left ventricular systolic dysfunction in mice and application of ultrasonic strain detection technology
Xin Ma, Fu-Xin Wan, Na Gao, Jing Xu, Tomasz Urbanowicz, Dhruv Nayyar, Qin Wang
Journal of Thoracic Disease  
2025;
17
(11)
:10459-10470
.

Brief Report

Consensus map for robotic right lower lobectomy—essential components for artificial intelligence and education applications
Arian Mansur, Christina L. Costantino, Lillian L. Tsai, Judith Amores, Sophia K. McKinley, Harald C. Ott, Hugh Auchincloss, Michael S. Kent, Inderpal S. Sarkaria, Richard S. Lazzaro, Stephen C. Yang, Daniel A. Hashimoto, Chi-Fu Jeffrey Yang, Lana Schumacher
Journal of Thoracic Disease  
2025;
17
(11)
:10471-10477
.

Review Article

Use of artificial humidification during non-invasive mechanical ventilation in patients with acute respiratory failure: a narrative review
Jorge Ricoy, Nuria Rodríguez-Núñez, Roi Soto-Feijóo, María E. Toubes, Lucía Ferreiro, Luis Valdés
Journal of Thoracic Disease  
2025;
17
(11)
:10478-10487
.
A narrative review of the early diagnosis and treatment of idiopathic pulmonary fibrosis with lung cancer
Haoxiang Qi, Xinhua Chai, Feng Zhou, Yuli Jiang, Yongxia Bao
Journal of Thoracic Disease  
2025;
17
(11)
:10488-10500
.
Lung and lobe torsion: a narrative review
Julian Brouillette, Ali Mokhtari, Emmanuelle Papleux, Apostolos C. Agrafiotis
Journal of Thoracic Disease  
2025;
17
(11)
:10501-10509
.
Analyzing pleural fluid attributes in SARS-CoV-2 infection: a systematic review
Roi Soto-Feijóo, Elisa Landín, Honorio Martínez-Martínez, María Carreiras, Ainoa Fanego, Lucía Ferreiro, Nuria Rodríguez-Núñez, María E. Toubes, Luis Valdés
Journal of Thoracic Disease  
2025;
17
(11)
:10510-10518
.
Revisiting optimal static lung preservation techniques in an era when machine perfusion is transforming organ recovery: thermoregulation is still an important concept
Norihisa Shigemura, Chadi A. Hage
Journal of Thoracic Disease  
2025;
17
(11)
:10519-10524
.
The central regulatory network of cough: a cornerstone of cough management
Shukun Wang, Jingjing Yang, Mengyue Su, Yu Feng, Xiuyun Zhang, Wei Li, Peng Sun
Journal of Thoracic Disease  
2025;
17
(11)
:10525-10540
.
Sustained breath-holds in bronchoscopy: a pause worth taking?—a narrative review
Ankush P. Ratwani, Jennifer D. Duke, Rafael Paez, Greta Bridwell, Samira Shojaee, Robert J. Lentz, Susan Eagle, Krish Bhadra, Fabien Maldonado
Journal of Thoracic Disease  
2025;
17
(11)
:10541-10550
.
Off-label use of lung sealants: the need for evidence-based guidelines and adequate indications for use
Bob P. Hermans, Wilson W. L. Li, Stefan M. van der Heide, Ad F. T. M. Verhagen
Journal of Thoracic Disease  
2025;
17
(11)
:10551-10557
.
Advantages of integrating artificial intelligence and spectral CT for lung nodule classification and prognostic judgment: a narrative review
Minyuan Zhong, Silong Li, Yi Wang, Yiyang Ma, Sixue Mao, Zonghui Huang, Huiyun Xiao, Yuguang Wang, Tianyu Zhang
Journal of Thoracic Disease  
2025;
17
(11)
:10558-10570
.
The value of continuous cough monitoring: a narrative review
Mindaugas Galvosas, Peter M. Small
Journal of Thoracic Disease  
2025;
17
(11)
:10571-10583
.

Letter to the Editor

Remnant cholesterol in chronic obstructive pulmonary disease—phenotypes and pharmacotherapy matter
Junfeng Hao, Xianbin Gu
Journal of Thoracic Disease  
2025;
17
(11)
:10584-10585
.
Methodological considerations for the Lianhua Qingwen capsule influenza prevention trial
Chunfang Xue, Jiaqian Chen
Journal of Thoracic Disease  
2025;
17
(11)
:10586-10587
.