Vol 17, No 5 (May 30, 2025): Journal of Thoracic Disease

Editorial

Viewpoints of investigator on CONSORT 2025 statement-updated guideline for reporting randomized trials
Tianxing Feng, Chouwen Zhu, Geliang Yang
Journal of Thoracic Disease  
2025;
17
(5)
:2752-2755
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 (30 May 2025) 
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Original Article

Assessing the efficacy and impact of minimally invasive thoracic surgery for diagnosing non-malignant pulmonary nodules
Jasmin Vargas, Efe Okunzuwa, Eric Hart, Kalvin Lung, Diego Avella-Patino, Samuel S. Kim, Ankit Bharat
Journal of Thoracic Disease  
2025;
17
(5)
:2756-2764
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 (30 May 2025) 
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Factors linked to lung cancer in MIMIC-IV database
Chengyuan Fang, Yuwen Bai, Yanzhong Xin, Luquan Zhang, Jianqun Ma
Journal of Thoracic Disease  
2025;
17
(5)
:2765-2777
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 (30 May 2025) 
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Enhancing survival in locally advanced esophageal cancer: a comparative analysis of neoadjuvant immunotherapy versus conventional neoadjuvant therapies using the SEER database
Qinyong Tian, Jingping Lin, Liudan Hu, Yimin Lin, Dingzhu Chen, Rongqiang Shen, Yi Zhang, Jinxin Xu, Lihua Chen
Journal of Thoracic Disease  
2025;
17
(5)
:2778-2801
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 (30 May 2025) 
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The epidemiology of chronic postsurgical pain after video-assisted thoracic surgery (VATS-CPSP) in China: a multicentre prospective study
Di Jin, Yuelun Zhang, Hui Zheng, Jingxiang Wu, Ke Wei, Jiange Han, E Wang, Fufen Meng, Yiri Du, Le Shen, Yuguang Huang
Journal of Thoracic Disease  
2025;
17
(5)
:2802-2812
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 (30 May 2025) 
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Predicting COVID-19 vaccination timing by integrating the theory of planned behavior and the diffusion of innovations: a cross-sectional survey in Macao, China
Wei He, Jianwei Wu, Caleb Huanyong Chen, Aaron Finley, Hui Wang, Hui Huang, Chanwa Ng, Tinyat Chui, Jinghua Zhang, Chitin Hon
Journal of Thoracic Disease  
2025;
17
(5)
:2813-2826
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 (30 May 2025) 
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Exploring and verifying key thin-section computed tomography features for accurately differentiating granulomas and peripheral lung cancers
Hong-Bo Xu, Fa-Jin Lv, Can Ding, Bin-Jie Fu, Wang-Jia Li, Jian-Qun Yu, Zhi-Gang Chu
Journal of Thoracic Disease  
2025;
17
(5)
:2827-2840
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 (30 May 2025) 
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Prognostic factors for non-small cell lung cancer after neoadjuvant therapy and surgery: a retrospective observational study
Yuxing Lin, Renjie Huang, Qing Liu, Xin Yan, Guoliang Liao, Maojie Pan, Jianting Du, Xian Gong, Jiekun Qian, Long Wu, Bin Zheng, Chun Chen, Zhang Yang
Journal of Thoracic Disease  
2025;
17
(5)
:2841-2855
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 (30 May 2025) 
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Efficacy evaluation of tyrosine kinase inhibitors for advanced non-small cell lung cancer patients with leptomeningeal metastasis
Yanhua Wang, Yue Hao, Manyi Xu, Lue Hong, Chunwei Xu, Zhengbo Song
Journal of Thoracic Disease  
2025;
17
(5)
:2856-2865
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 (30 May 2025) 
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A SEER prognostic nomogram analysis for extensive-stage small cell lung cancer: comparing the immune checkpoint inhibitors (ICIs) and non-ICIs eras
Xiaomei Jiang, Zhongqi Wang, Xiufeng Zhang, Liangyun Xie, Shanshan Ji, Qinqin Song, Jing Dong, Ye Jin, Shuangli Li, Zhi Zhang, Xuemei Zhang
Journal of Thoracic Disease  
2025;
17
(5)
:2866-2887
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 (30 May 2025) 
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Prognosis of critically ill immunocompromised patients with COVID-19 admitted for acute respiratory failure: a retrospective propensity score analysis
Océane Bernard de Lajartre, Alexia Le Corre, Anaelle Bichon, Nicolas Terzi, Arnaud Gacouin, Adel Maamar, Jean-Marc Tadie
Journal of Thoracic Disease  
2025;
17
(5)
:2888-2900
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 (30 May 2025) 
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Evaluating long-term bronchoscopic outcomes of tracheobronchoplasty in patients with expiratory central airway collapse
Bryan F. Vaca-Cartagena, Rodrigo Funes-Ferrada, Alanna Barrios-Ruiz, Sofia Valdes-Camacho, Alejandra Yu Lee-Mateus, Kelly S. Robertson, Sebastian Fernandez-Bussy, Mathew Thomas, Ian A. Makey, David Abia-Trujillo
Journal of Thoracic Disease  
2025;
17
(5)
:2901-2911
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 (30 May 2025) 
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Utilizing spectral detector computed tomography quantitative parameters via multimodality tumor tracking to predict occult lymph node metastasis in clinical stage 1 pure solid lung adenocarcinoma
Kaifang Liu, Yang Cao, Yiyang Gao, Yu Zhu, Kai Luo, Youtao Xu, Yinsu Zhu, Xiaodong Xie
Journal of Thoracic Disease  
2025;
17
(5)
:2912-2925
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 (30 May 2025) 
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Sarcopenic psoas muscle surface area predicts short and long-term mortality for oesophageal cancer patients
Emma Annukka Tiainen, Erkki-Ville Sakari Wirta, Tuula Marjatta Tyrväinen, Johanna Marja Laukkarinen, Mika Tapani Ukkonen
Journal of Thoracic Disease  
2025;
17
(5)
:2926-2936
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 (30 May 2025) 
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Comparison of neoadjuvant chemotherapy plus immunotherapy versus chemoradiotherapy for esophageal squamous cell carcinoma patients: efficacy and safety outcomes
Shuming Shi, Li Li, Hao Zhou, Fuhao Xu, Ning Liu, Dexian Zhang, Shuanghu Yuan
Journal of Thoracic Disease  
2025;
17
(5)
:2937-2946
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 (30 May 2025) 
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Four-year outcomes with perioperative toripalimab plus chemotherapy in resectable stage III non-small cell lung cancer (NeoTAP01 study)
Yuheng Zhou, Zerui Zhao, Wenyu Zhai, Shoucheng Feng, Weizhen Sun, Yaobin Lin, Hao Long
Journal of Thoracic Disease  
2025;
17
(5)
:2947-2957
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 (30 May 2025) 
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Segmental bronchial marking method using indocyanine green for safe thoracoscopic segmentectomy: a single-center early experience
Satoshi Takamori, Marina Nakatsuka, Hikaru Watanabe, Jun Suzuki, Makoto Endo, Satoshi Shiono
Journal of Thoracic Disease  
2025;
17
(5)
:2958-2966
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 (30 May 2025) 
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The relationship between blood biomarkers and prognosis of pathologic stage IA pure-solid non-small cell lung cancer patients
Jianlong Bu, Pinyi Zhang, Pengju Li, Yubo Yan, Mengfeng Liu, Xiaoqi Wu, Junfeng Wang, Changfa Qu
Journal of Thoracic Disease  
2025;
17
(5)
:2967-2979
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 (30 May 2025) 
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Biventricular remodeling after cone repair in Ebstein anomaly: magnetic resonance imaging data analysis
Jae Hong Lim, Chang-Ha Lee, Sungkyu Cho, Eung Re Kim, Yong Jin Kim
Journal of Thoracic Disease  
2025;
17
(5)
:2980-2988
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 (30 May 2025) 
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Impact of perineural invasion in thoracic esophageal squamous cell carcinoma—a retrospective study with long-term follow-up outcomes
Jicheng Xiong, Simiao Lu, Shuoming Liang, Hainan Chen, Ziwei Wang, Hao Meng, Yehan Zhou, Qifeng Wang, Yan Miao, Qin Xie, Guangyuan Liu, Kangning Wang, Lin Peng, Qiang Fang, Wenguang Xiao, Yongtao Han, Xuefeng Leng
Journal of Thoracic Disease  
2025;
17
(5)
:2989-3003
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 (30 May 2025) 
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Effects of intraoperative non-steroidal anti-inflammatory drugs on early postoperative pulmonary complications following lung resection: a retrospective propensity score-matched study
Wenzhi Zhu, Jing Ma, Xiaoyi Wang, Hongyu Tan
Journal of Thoracic Disease  
2025;
17
(5)
:3004-3014
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 (30 May 2025) 
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Risk factors for cough after pulmonary resection in patients with non-small cell lung cancer: a systematic review and meta-analysis
Zhenyi Li, Rongyang Li, Zhan Zhang, Yukai Wang, Sijie Zhang, Haiming Li, Lin Li, Hui Tian
Journal of Thoracic Disease  
2025;
17
(5)
:3015-3031
.
 (30 May 2025) 
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Association between red blood cell distribution width to albumin ratio (RAR) and long-term prognosis of patients with sudden cardiac arrest
Fan Li, Junjie Li, Zijian Liu, Chen Zeng, Hongyan Wei, Keke Wang
Journal of Thoracic Disease  
2025;
17
(5)
:3032-3052
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 (30 May 2025) 
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Long-term outcomes of modified enhanced recovery after surgery (mERAS) protocols in peri-operative management of minimally invasive esophagectomy
Bin Zheng, Maohui Chen, Yizhou Huang, Taidui Zheng, Shuliang Zhang, Wei Li, Chun Chen
Journal of Thoracic Disease  
2025;
17
(5)
:3053-3063
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 (30 May 2025) 
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Malignant pleural effusion is a negative prognostic factor for immunotherapy outcomes in non-small cell lung cancer: a single-center retrospective study
Jing Wang, Boyue Pang, Jiali Zhang, Xiubao Ren, Ying Han
Journal of Thoracic Disease  
2025;
17
(5)
:3064-3072
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 (30 May 2025) 
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The impact of perceval sutureless aortic valve in multiple valve surgery: implications of short- and mid-term outcomes—a propensity score matched study
Jung-Hoon Shin, Hyun-Chul Joo, Jung-Hwan Kim, Sak Lee, Young-Nam Youn, Seung-Hyun Lee
Journal of Thoracic Disease  
2025;
17
(5)
:3073-3084
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 (30 May 2025) 
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Pneumonectomy after neoadjuvant immunotherapy combined with chemotherapy is a safe and effective option for central non-small-cell lung cancer patients, a single-center experience
Tao Cheng, Xiaolong Huang, Huiqin Yang, Chunlai Lu, Teng Ma, Fengkai Xu, Jie Gu, Di Ge
Journal of Thoracic Disease  
2025;
17
(5)
:3085-3096
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 (30 May 2025) 
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Prognostic value of cardiac biomarkers in surgery for acute type A aortic dissection: mid-term follow-up results
Sangyu Zhou, Yanxiang Liu, Bowen Zhang, Luchen Wang, Mingxin Xie, Haoyu Wang, Xiaogang Sun
Journal of Thoracic Disease  
2025;
17
(5)
:3097-3105
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 (30 May 2025) 
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Tracheostomy in COVID-19 critically ill patients: a bibliometric and visual analysis
Raffaele Merola, Stefania Troise, Antonio Romano, Maria Vargas
Journal of Thoracic Disease  
2025;
17
(5)
:3106-3117
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 (30 May 2025) 
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Safety, efficacy, and postoperative pulmonary function recovery of uniportal and multiportal thoracoscopic lung segmentectomy
Xinyu Guo, Dajiang Liu, Zhuang Shao, Yongsheng Meng, Bingyang Huang, Xiaoyong Song
Journal of Thoracic Disease  
2025;
17
(5)
:3118-3127
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 (30 May 2025) 
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Survival outcome after systematic lymphadenectomy in non-small cell lung cancer according to the latest proposed edition of the TNM system
Mohamed Haj Khalaf, Hayk Kikoyan, Denis Trufa, Mostafa Higaze, Koblandy Khamitov, Chirag Parjiea, Olena Stets Romaniwna, Arndt Hartmann, Ralf Rieker, Horia Sirbu
Journal of Thoracic Disease  
2025;
17
(5)
:3128-3137
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 (30 May 2025) 
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Predictors of successful closure following open-window thoracostomy in patients with empyema: a single-center retrospective cohort study
Hiroki Matsumiya, Masataka Mori, Katsuma Yoshimatsu, Rintaro Oyama, Natsumasa Nishizawa, Masatoshi Kanayama, Akihiro Taira, Shinji Shinohara, Taiji Kuwata, Masaru Takenaka, Koji Kuroda, Fumihiro Tanaka
Journal of Thoracic Disease  
2025;
17
(5)
:3138-3146
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 (30 May 2025) 
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Perioperative outcomes of uniportal video-assisted thoracoscopic lobectomy in scope operation performed by a clinical engineer
Hidenori Goto, Kozo Nakanishi
Journal of Thoracic Disease  
2025;
17
(5)
:3147-3156
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 (30 May 2025) 
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First-line serplulimab-based immunochemotherapy in elderly patients with extensive-stage small cell lung cancer: a multicenter, real-world study
Meiqi Shi, Wenyue Yang, Yun Zhou, Xiaodong Xia, Min Zhou, Xinli Zhou, Jialei Wang
Journal of Thoracic Disease  
2025;
17
(5)
:3157-3169
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 (30 May 2025) 
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A retrospective study on the prognosis of patients with small cell lung cancer with or without interstitial pneumonia treated with postoperative chemotherapy
Mikihito Saito, Go Saito, Mitsuhiro Abe, Akira Nishiyama, Masayuki Ota, Hidemi Suzuki, Ichiro Yoshino, Yuichi Takiguchi, Takuji Suzuki
Journal of Thoracic Disease  
2025;
17
(5)
:3170-3181
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 (30 May 2025) 
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Critical role of spread through air spaces in prognosis of stage IA3 non-small cell lung cancer: insights from a real-world multicenter study
Shaobin Yu, Zhifan Zhang, Xiao Han, Chen Hui, Guibin Huang, Guofeng Yang, Shuchen Chen
Journal of Thoracic Disease  
2025;
17
(5)
:3182-3199
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 (30 May 2025) 
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Clinical outcomes of subxiphoid uniportal video-assisted thoracoscopic thymectomy using a double sternum retractor versus conventional approaches
Weiyang Chen, Hongtao Tang, Zengwei Yu, Lei Wang, Jie Li, Lin Lin, Jinlan Zhao, Qing Liu, Chunyan Zhao, Lin Ma, Wenya Li, Longqi Chen, Dong Tian
Journal of Thoracic Disease  
2025;
17
(5)
:3200-3209
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 (30 May 2025) 
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Challenges and current practices in the management of pulmonary nodules in China: a mixed methods study
Dan Chen, Liduo Shao, Yuxing Dong, Changjiang Lyu, Yuichi Saito, Alberto Salvicchi, Jie Gu, Jiping Shen, Jing Cang
Journal of Thoracic Disease  
2025;
17
(5)
:3210-3222
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 (30 May 2025) 
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A systematic review and meta-analysis of artificial intelligence software for tuberculosis diagnosis using chest X-ray imaging
Zhi-Lin Han, Yu-Yang Zhang, Jian Li, Shan Gao, Wei Liu, Wan-Jie Yang, Zhi-Heng Xing
Journal of Thoracic Disease  
2025;
17
(5)
:3223-3237
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 (30 May 2025) 
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The effects of a modified deep serratus anterior plane block on surgical stress and perioperative neurocognitive disorders in elderly patients undergoing thoracic surgery: a randomized clinical study
Weiping Lei, Jiating Cheng, Elena Bignami, Michel Gonzalez, Qirui Sun, Jianliang Sun, Yuan Cheng
Journal of Thoracic Disease  
2025;
17
(5)
:3238-3248
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 (30 May 2025) 
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Comparative evaluation of deep learning-based and conventional reconstruction techniques for image quality enhancement in low-dose chest computed tomography
Zhengyu Zhang, Chong Liu, Shujuan Zhou, Xianfeng Yang, Romaric Loffroy, Hae Won Kim, Lei Shan
Journal of Thoracic Disease  
2025;
17
(5)
:3249-3258
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 (30 May 2025) 
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The value of chromosome 8 heteroploid tumor cells in the peripheral blood and pleural effusion in evaluating treatment efficacy and the prognosis of metastatic non-small cell lung cancer patients
Hanqing Yao, Zhengdong Wang, Junjun Yang, Alfredo Tartarone, Yusuke Tomita, Xingxiang Xu, Yong Song
Journal of Thoracic Disease  
2025;
17
(5)
:3259-3271
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 (30 May 2025) 
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Aortic valve calcification in echocardiography is a prognostic factor for short-term adverse outcomes in elderly patients with severe COVID-19: a retrospective cohort study
Xinyi Zhu, Lin Jiang, Chao Tang, Fei Shi, Jing Zhu, Wei Qian
Journal of Thoracic Disease  
2025;
17
(5)
:3272-3282
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 (30 May 2025) 
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Transcriptome analysis and artificial intelligence for predicting lymph node metastasis of esophageal squamous cell carcinoma
Zhengang Zhao, Yujie Xie, Dongmei Lai, Jin Liang, Ikenna C. Okereke, Wanli Lin
Journal of Thoracic Disease  
2025;
17
(5)
:3283-3296
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 (30 May 2025) 
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Application and validation of a newly developed lung donor (LUNDON) acceptability score for lung transplantation: a retrospective cohort study
Feng Liu, Yifeng Huang, Chaojian Chen, Leyan Chen, Xin Huang, Zhouzi Dong, Huachi Jiang, Yijun He, Wujun Xue
Journal of Thoracic Disease  
2025;
17
(5)
:3297-3306
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 (30 May 2025) 
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Basic fibroblast growth factor-loaded hydrogel biomaterial patches for promoting the healing of esophageal anastomosis: an experimental animal study
Chengdong Liu, Yun Ding, Yiyuan Yang, Kenan Huang, Rongqiang Wei, Zhifei Xu, Zhigang Cai, Hua Tang
Journal of Thoracic Disease  
2025;
17
(5)
:3307-3317
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 (30 May 2025) 
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Clinical outcomes of contezolid in treating complex tuberculosis: real-world evidence from 11 patients
Ying Liu, Zixuan Cui, Yingxi Fu, Edward D. Chan, Chunmei Hu
Journal of Thoracic Disease  
2025;
17
(5)
:3318-3325
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 (30 May 2025) 
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Development and validation of a prognostic model for overall survival in pN0 esophageal cancer patients after neoadjuvant chemotherapy: a SEER database-based study
Pengjie Yang, Ting Yang, Tianlai Liu, Mengfei Sun, Jingjing Zhang, Berend J. van der Wilk, Dehui Zhao, Benben Zhu
Journal of Thoracic Disease  
2025;
17
(5)
:3326-3344
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 (30 May 2025) 
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Perioperative outcomes of median sternotomy for intrathoracic tracheal malignancies: a 15-year retrospective analysis
Anshun Zhu, Yunxuan Jia, Danyang Hou, Paolo A. Ferrari, Roberto Tonelli, Takahiro Homma, Chenxi Zhong, Haitang Yang, Feng Yao
Journal of Thoracic Disease  
2025;
17
(5)
:3345-3356
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 (30 May 2025) 
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Bioinformatics-based screening of genes associated with dilated cardiomyopathy
Yanghua Liu, Qingshan Wu, Fangni Mo, Ye Mai, Shengyuan Zhang, Xiang Wu
Journal of Thoracic Disease  
2025;
17
(5)
:3357-3369
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 (30 May 2025) 
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The value of the monocyte to high-density lipoprotein cholesterol ratio in predicting the thrombosis burden and long-term prognosis of acute myocardial infarction patients: a retrospective cohort study
Youpeng Wang, Juncang Duan, Sanjana Nagraj, Yong Hoon Kim, Yibin Pan
Journal of Thoracic Disease  
2025;
17
(5)
:3370-3379
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 (30 May 2025) 
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Identification of esophageal cancer tumor antigens and immune subtypes for guiding vaccine development
Ruiqi Liu, Yanrong Chen, Xiaodong Xu, Qiang Xue, Hongmei Gu
Journal of Thoracic Disease  
2025;
17
(5)
:3380-3399
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 (30 May 2025) 
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PIASy deficiency mitigates thoracic aortic aneurysm formation via the TGF-β/Smad2/3 pathway
Dafu Shen, Hui Zheng, Kejie Shao, Jingze Zhu, Yucheng Hou, Yinglong Ding
Journal of Thoracic Disease  
2025;
17
(5)
:3400-3409
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 (30 May 2025) 
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Review Article

Reducing barriers to care in the treatment of lung cancer: a narrative review
Robert M. Van Haren, Meera Mathur, Alique G. Topalian, Allison N. Moore, Catherine G. Pratt, Shesh Rai, Melinda Butsch Kovacic, John Kues
Journal of Thoracic Disease  
2025;
17
(5)
:3410-3418
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 (30 May 2025) 
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Demographics, risk factors and prevalence of chronic cough in Asian general adult population: a narrative review
Xuwen Yang, Mengjia Hu, Kewu Huang
Journal of Thoracic Disease  
2025;
17
(5)
:3419-3432
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 (30 May 2025) 
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Statins as potential adjuvant therapy in lung cancer: a narrative review
Ye Tian, Jinbao Li, Xueying Yang
Journal of Thoracic Disease  
2025;
17
(5)
:3433-3449
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 (30 May 2025) 
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Pulmonary ossification: a review
Ana Casal, Lucía Ferreiro, María Elena Toubes, Luis Valdés
Journal of Thoracic Disease  
2025;
17
(5)
:3450-3455
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 (30 May 2025) 
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Brief Report

Correlation of inflammatory markers with progression-free survival in advanced lung cancer patients treated with immune checkpoint inhibitors in combination with chemotherapy: a real-world study
Shijun Li, Cuicui Zhang, Xinyue Wang, Jing Wang, Kai Li
Journal of Thoracic Disease  
2025;
17
(5)
:3456-3463
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 (30 May 2025) 
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Versatility of disposable scopes and their use in flexible, semi-rigid and rigid thoracoscopy
Rodrigo Garcia Tome, Ara Vartanyan, Chongiin Kim, Scott Oh
Journal of Thoracic Disease  
2025;
17
(5)
:3464-3471
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 (30 May 2025) 
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Editorial Commentary

Perioperative toripalimab and chemotherapy in resectable non-small cell lung cancer: another weapon in the armamentarium
Courtney H. Coschi, Peter M. Ellis
Journal of Thoracic Disease  
2025;
17
(5)
:3472-3477
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 (30 May 2025) 
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Clinical significance of mirtazapine for anorexia in patients with non-small cell lung cancer
Hisao Imai, Kyoichi Kaira, Hiroshi Kagamu
Journal of Thoracic Disease  
2025;
17
(5)
:3478-3483
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 (30 May 2025) 
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