Vol 17, No 3 (March 31, 2025): Journal of Thoracic Disease

Editorial

Pectus excavatum revision surgery: a complex challenge requiring centralization of expertise
Nicky Janssen, Elise J. van Polen, Jean H. T. Daemen, Aimée J. P. M. Franssen, Karel W. E. Hulsewé, Yvonne L. J. Vissers, Hans G. Van Veer, Frank V. de Paoli, Erik R. de Loos
Journal of Thoracic Disease  
2025;
17
(3)
:1126-1130
.

Original Article

Risk factors and age-specific monthly patterns of primary spontaneous pneumothorax: a multicenter study
Seung Keun Yoon, Hee Kyung Kim, Jiyun Lee, Young-Du Kim, Deog Gon Cho
Journal of Thoracic Disease  
2025;
17
(3)
:1131-1141
.
Comorbidities associated with adult asthma according to severity: analysis of data from the National Health Insurance Sharing Service
Jung-Hyun Kim, Bo Young Park, Sun Hee Choi, Hyouk-Soo Kwon, Woo-Jung Song, Jinho Yu, Dae Jin Song, Yoon-Seok Chang, You Sook Cho, Dae Hyun Lim, Young-Joo Cho, Suk-Il Chang, Sae-Hoon Kim, Tae-Bum Kim
Journal of Thoracic Disease  
2025;
17
(3)
:1142-1158
.
Bronchial thermoplasty reduces asthma exacerbation and improves quality of life in asthma with type 2 inflammation
Thanyaporn Angsuwatcharakorn, Chatuthanai Savigamin, Vorawut Thanthitaweewat, Nophol Leelayuwatanakul, Kamon Kawkitinarong, Sarita Thawanaphong, Amornpun Wongkarnjana, Nattapong Jaimchariyatam, Ketsupar Jirakran, Chanchai Sittipunt, Thitiwat Sriprasart
Journal of Thoracic Disease  
2025;
17
(3)
:1159-1168
.
IRF8 and CD2 are potential targets of immunotherapy in non-small cell lung cancer
Zhen Gao, Rui Han, Qinghao Chen, Jichao Guo, Yancheng Wang, Qian Hong, Chenguang Zhao, Juwei Mu, Jiagen Li
Journal of Thoracic Disease  
2025;
17
(3)
:1169-1184
.
Comparison of patient-reported outcomes after uniportal versus multiportal video-assisted thoracoscopic sub-lobar resection
Xiang-Lin Li, De-Zhao Tang, Yi-Zhang Chen, Zi-Ying Li, Yong Tang, Cheng Deng, Qiu-Ling Shi, Gui-Bin Qiao
Journal of Thoracic Disease  
2025;
17
(3)
:1185-1196
.
Development and validation of a nomogram for predicting pulmonary embolism in patients with pulmonary tuberculosis
Haobo Kong, Yingying Sang, Jingjing Pan, Min Liang, Zhi Geng, Ye Li
Journal of Thoracic Disease  
2025;
17
(3)
:1197-1206
.
Influencing factors of 90-day readmission of patients with heart failure based on the MIMIC-IV database
Xiaohua Shen, Jiahui Yang, Xiaoyan Zhang
Journal of Thoracic Disease  
2025;
17
(3)
:1207-1216
.
Video-assisted thoracoscopy with two-lung ventilation and CO2 insufflation in primary spontaneous pneumothorax: propensity score matching comparison
Ying Jie Cui, Wen Xue Piao, Yong Chae Jung, Hyun Jin Cho, Min-Woong Kang
Journal of Thoracic Disease  
2025;
17
(3)
:1217-1227
.
Emerging trends and hotspots in chronic obstructive pulmonary disease and oxidative stress: a bibliometric and visualized analysis from 2010 to 2024
Rui Wang, Shujie Feng, Jiajie Jiang, Yonglong Chang, Yanping Zong, Jinchen Guo
Journal of Thoracic Disease  
2025;
17
(3)
:1228-1248
.
Echocardiographic characteristics of paravalvular leak following surgical aortic valve replacement: a retrospective cohort study
Yuri Hayashi, Joshua K. Russell, Cody J. Dvorak, Milena A. Gebska, Satoshi Hanada, Arun K. Singhal
Journal of Thoracic Disease  
2025;
17
(3)
:1249-1258
.
Effect of needle aspiration for treatment of moderate to severe non-tension pneumothorax after transthoracic needle biopsy
Jong Hwan Jeong, Ho Cheol Kim, Jae Seung Lee, Chang-Min Choi, Wonjun Ji
Journal of Thoracic Disease  
2025;
17
(3)
:1259-1267
.
The role of the stapled interlobar fissure position for intraoperative detection and postoperative diagnosis of middle lobe torsion after right upper lobectomy
Kazuto Ohtaka, Setsuyuki Ohtake, Aki Fujiwara-Kuroda, Sho Narita, Shinya Otsuka, Hiroshi Yamasaki, Akihiro Sasaki, Haruhiko Shiiya, Hideki Ujiie, Masato Aragaki, Tatsuya Kato
Journal of Thoracic Disease  
2025;
17
(3)
:1268-1277
.
Clinical characteristics of the early responders in the treatment of chronic cough
Tai Joon An, Ji Hyun Shin, Seohyun Kim, Chin Kook Rhee, Ji-Yong Moon, Jin Woo Kim, Hyoung Kyu Yoon
Journal of Thoracic Disease  
2025;
17
(3)
:1278-1288
.
Nomogram for predicting the prognosis of metastatic thymic epithelial tumors
Caiwen Huang, Hui Liu, Qihua Zou, Liping Kang, Jianliang Mai, Yongbin Lin, Ying Liang
Journal of Thoracic Disease  
2025;
17
(3)
:1289-1300
.
Implementing a chest tube removal protocol in patients with thoracic trauma: a prospective clinical study
Yassir Abdulrahman, Mushreq Al-Ani, Mohammed Farhat, Hosam Khallafalla, Ahmad Abu Amr, Ahmed Ajaj, Ammar Al-Zubaidi, Talat Chughtai, Ayman El-Menyar, Mohammad Asim, Sandro Rizoli, Hassan Al-Thani
Journal of Thoracic Disease  
2025;
17
(3)
:1301-1311
.
Role of radiation alone vs. concurrent chemoradiotherapy in surgically ineligible patients with tracheobronchial squamous cell carcinoma
Jeong Yun Jang, Hongryull Pyo, Kyungmi Yang, Jae Myoung Noh, Jeong Ha Lee
Journal of Thoracic Disease  
2025;
17
(3)
:1312-1322
.
Efficacy and safety of different forms of ablation therapies and antiarrhythmic drugs in atrial fibrillation: a systematic review and network meta-analysis of randomized clinical trials
Qinghua Chen, Xiaoqi Xiong, Longchang Li, Chun Gui
Journal of Thoracic Disease  
2025;
17
(3)
:1323-1334
.
Implementation of a robotic-assisted thoracic surgery program for anatomical lung resections, a single surgeon’s experience
Andreas Westerlind, Maya Landenhed-Smith, Carl-Johan Malm, Göran Dellgren
Journal of Thoracic Disease  
2025;
17
(3)
:1335-1348
.
Construction and analysis of the invasive prediction model for pulmonary nodules: based on clinical, CT image and DNA methylation characteristics
Qingjie Yang, Xiaoyan Sun, Shenghua Lv, Qingtian Li, Linhui Lan, Ningquan Liu, Mingyang Wang, Kaibao Han, Xinhai Feng
Journal of Thoracic Disease  
2025;
17
(3)
:1349-1363
.
The significance of periostin in the diagnosis of idiopathic pulmonary fibrosis and prediction of acute exacerbations
Shi Wu, Hua Liu, Shijia Yin, Yun Wang, Xiaoxiao Liu, Zhen Ding
Journal of Thoracic Disease  
2025;
17
(3)
:1364-1376
.
Krebs von den Lungen-6 as a biomarker for distinguishing between interstitial lung disease and interstitial lung abnormalities based on computed tomography findings
Jin Hwa Song, Hye-Rin Kang, Keun-Beom Cheong
Journal of Thoracic Disease  
2025;
17
(3)
:1377-1386
.
Predicting the clinical prognosis of non-small cell lung cancer patients by predicting ALOX5 expression: a radiomics model
Peihong Hu, Mingxin Liu, Hang Gu, Haoran Liu, Qiang Li, Bo Tian
Journal of Thoracic Disease  
2025;
17
(3)
:1387-1399
.
Asthma-derived genetic signature predicts lung cancer prognosis: a multi-scale omics investigation
Youpeng Chen, Enzhong Li, Yifei Xie, Zhenglin Chang, Xiaoyi Chen, Haojie Wu, Weilin Feng, Zhangkai J. Cheng, Baoqing Sun
Journal of Thoracic Disease  
2025;
17
(3)
:1400-1423
.
Comparative efficacy and safety of inhaled antibiotics in managing chronic Pseudomonas aeruginosa infection in patients with cystic fibrosis and bronchiectasis: a systematic review and network meta-analysis
Yifan Chen, Xiao Meng, Jiaxin Zhu, Shengxiao Lai, Zixuan Liu, Zhizhou Dou, Yaozhou Wu, Li Wei
Journal of Thoracic Disease  
2025;
17
(3)
:1424-1443
.
Diagnostic value of GeneXpert MTB/RIF in bronchoalveolar lavage fluid for pulmonary non-tuberculosis mycobacterial in acid-fast stain smear-positive and GeneXpert MTB/RIF-negative cases
Zhengxing Wu, Jichan Shi, Chaochao Qiu, Yueying Zhou, Ning Pan, Lianpeng Wu, Xiangao Jiang
Journal of Thoracic Disease  
2025;
17
(3)
:1444-1451
.
Epidemiological trends and serological profiles of respiratory pathogens in Guangzhou: an 11-year retrospective study from 2013 to 2023
Wenhan Cao, Huimin Huang, Zhenglin Chang, Zhiman Liang, Yanting Fang, Lixian Li, Haiyang Li, Yu Guo, Yuqi Chen, Chengtao Zhou, Zixin Chen, Zhangkai J. Cheng, Baoqing Sun
Journal of Thoracic Disease  
2025;
17
(3)
:1452-1468
.
Early and midterm outcomes of concomitant coronary artery bypass grafting for coronary artery disease in surgical repair of type A aortic dissection
Ling-Chen Huang, Yang-Xue Sun, Ze-Hua Shao, Xiang-Yang Qian, Cun-Tao Yu, Hong-Wei Guo
Journal of Thoracic Disease  
2025;
17
(3)
:1469-1480
.
Single-port inflatable mediastinoscopy combined with laparoscopic esophagectomy via right cervical auxiliary operating port and sternal lifting: a safe and reliable surgical method
Jiang-Shan Huang, Wen-Wei Lin, Qi-Hong Zhong, Fei-Long Guo, Jing-Yu Wu, Zhen-Yang Zhang, Jiang-Bo Lin
Journal of Thoracic Disease  
2025;
17
(3)
:1481-1490
.
Deficiency of Toll-like receptor 4 attenuates airway inflammation and remodeling in an ovalbumine-induced mouse asthma model
Lixia Hou, Sijia Song, Bo Xiao, Zhimei Li, Bingxi Zhang, Xinru Feng, Biwen Mo, Dong Yao
Journal of Thoracic Disease  
2025;
17
(3)
:1491-1501
.
The synergistic effects of PM2.5 and high-fat diet on Th1/Th2 balance in model mice with asthma
Ruifeng Bai, Bingqian Liu, Tianshui Li, Heng Zhou, Xinyang Yue, Ying Liu, Yining Shan, Zhigang Li, Yongjie Wei, Jun Wu
Journal of Thoracic Disease  
2025;
17
(3)
:1502-1511
.
Clinical outcomes of caregiver-led indwelling pleural catheter care and drainage at a Singapore tertiary referral hospital
Brian Lee Wei Chua, Si Ling Young, Qiao Li Tan, Carrie Kah-Lai Leong, Jane Jing Yi Wong, Ivana Gilcrist Chiew Sian Phua, Wen Ting Lim, Ken Junyang Goh
Journal of Thoracic Disease  
2025;
17
(3)
:1512-1519
.
A risk score to predict postoperative complications in patients with resectable non-small cell lung cancer
Makhmudbek Mallaev, Nikolay Tsvetkov, Urs Simmen, Helga Bachmann, David König, Sacha I. Rothschild, Michael Tamm, Aljaz Hojski, Didier Lardinois
Journal of Thoracic Disease  
2025;
17
(3)
:1520-1530
.
Comparing erector spinae plane (ESP) and thoracic paravertebral (TPV) block analgesic effect after elective video-assisted thoracic surgery: a randomized, multiple-blinded, non-inferiority trial
Roberto Dossi, Miriam Patella, Barbara Barozzi, Gaston Dellaferrera, Adele Tessitore, Isabella Gimigliano, Stefano Cafarotti, Andrea Saporito
Journal of Thoracic Disease  
2025;
17
(3)
:1531-1540
.
The value of fibrosis score and 18F-FDG by positron emission tomography-computed tomography in lung cancer patients with interstitial lung disease
Rui Xu, Lijie Yin, Guangliang Qiang, Liping Fu
Journal of Thoracic Disease  
2025;
17
(3)
:1541-1551
.
Risk factors for pulmonary embolism: a case-control study
Geng Yang, Shaoping Nie
Journal of Thoracic Disease  
2025;
17
(3)
:1552-1560
.
Completion lobectomy after thoracoscopic segmentectomy on the left side should be approached with thoracotomy
Stefano Bongiolatti, Giovanni Mugnaini, Alberto Salvicchi, Alessandro Gonfiotti, Sara Borgianni, Domenico Viggiano, Luca Voltolini
Journal of Thoracic Disease  
2025;
17
(3)
:1561-1569
.
Comparison of laser-guided technology and conventional manual percutaneous lung biopsy: a single-center retrospective study
Zijian Li, Shuo Hu, Lei Leng, Cheng Ding, Jun Zhao, Li Ye, Xinyu Song, Ziqing Shen
Journal of Thoracic Disease  
2025;
17
(3)
:1570-1579
.
Effect of respiratory phase on three-dimensional quantitative parameters of pulmonary subsolid nodules in low-dose computed tomography screening for lung cancer
Hanxiao Zhang, Wenting Tu, Zhengwei Zhang, Xiuxiu Zhou, Li Fan, Shiyuan Liu
Journal of Thoracic Disease  
2025;
17
(3)
:1580-1592
.
Characteristics of symptoms among outpatients following the discontinuation of the dynamic zero-COVID-19 policy in China: insights from an online nationwide cross-sectional survey in 2022
Yunfu Wu, Mingming Wang, Xing Lv, Jie Chen, Liqiang Song
Journal of Thoracic Disease  
2025;
17
(3)
:1593-1604
.
Tetramethylpyrazine mitigates lipopolysaccharide-induced acute lung injury by inhibiting the HMGB1/TLR4/NF-κB signaling pathway in mice
Xu He, Guo-Feng Chen, Wei-Ting Tao, Xiao-Jia Huang, Ye Lin, Jing Sun, Yan Li
Journal of Thoracic Disease  
2025;
17
(3)
:1605-1616
.
Lifestyle change during the COVID-19 pandemic in Japan: implications for continuous positive airway pressure adherence in obstructive sleep apnea patient
Yo Suzuki, Ayako Inoshita, Naoko Sata, Erina Ishimizu, Shoko Suda, Ryo Naito, Takatoshi Kasai, Fumihiko Matsumoto
Journal of Thoracic Disease  
2025;
17
(3)
:1617-1625
.
Single-port compared to multi-port video-assisted thoracoscopic esophagectomy: a propensity-matched study
Guibin Weng, Weikun Su, Alfonso Fiorelli, Yijin Lin, Lin Chen, Hong Zhang, Weimin Fang
Journal of Thoracic Disease  
2025;
17
(3)
:1626-1635
.
Increased expression of FBW7 may improve the prognosis of lung adenocarcinoma after pemetrexed chemotherapy by transforming the epithelial-to-mesenchymal process
Jun Chen, Haiyan Pan, Yingying Zhou, Liyun Xu, Nawa Lin, Hanibal Bohnenberger, Zhijun Chen
Journal of Thoracic Disease  
2025;
17
(3)
:1636-1644
.
Development and validation of CT radiomics diagnostic models: differentiating benign from malignant pulmonary nodules and evaluating malignancy degree
Jun Zhu, Jiayu Tao, Maoshan Zhu, Jiaqiang Liu, Chonggang Ma, Ke Chen, Yuxuan Wang, Xiaochen Lu, Yuichi Saito, Bin Ni
Journal of Thoracic Disease  
2025;
17
(3)
:1645-1672
.
The value of perioperative neutrophil-to-lymphocyte ratio combined with the prognostic nutritional index for predicting anastomotic leakage after minimally invasive esophagectomy
Xianneng He, Jinxian He, Haofeng Cen, Inderpal S. Sarkaria, Noriyuki Hirahara, Chengbin Lin, Keyun Zhu, Weiyu Shen
Journal of Thoracic Disease  
2025;
17
(3)
:1673-1683
.
Development and validation of multi-sequence magnetic resonance imaging radiomics models for predicting tumor response to radiotherapy in locally advanced non-small cell lung cancer
Shangqun Liu, Yan Lv, Liwen Duan, Chengcheng Wang, Helong Wang, Songliu Hu, Baptiste Abbar, Jianyu Xu
Journal of Thoracic Disease  
2025;
17
(3)
:1684-1697
.
Association of interferon regulator factor 1 upregulation with pulmonary arterial hypertension
Yuheng Ye, Min Zhou, Di Yin, Yi Wang, Jiancheng Lin, Jiayan Sun, Xiaowan Wang, Qiang Guo
Journal of Thoracic Disease  
2025;
17
(3)
:1698-1710
.
Evaluation of the efficacy and safety of neoadjuvant immunotherapy in locally advanced esophageal squamous cell carcinoma
Mingxi Wang, Dandan Wei, Zhen Cui, Yangyang Zhou, Chuntong Yin, Zhengguang Zhou, Xavier Benoit D’Journo, Guowen Wang
Journal of Thoracic Disease  
2025;
17
(3)
:1711-1722
.
Relationship between the expression of striated preferentially expressed gene (SPEG) and the development of atrial fibrillation
Jiaochang Wei, Lanqing Yu, Yuhua Liu, Shaowu Ye, Bo Song, Yimin Deng, Qian Lu, Bailu Deng
Journal of Thoracic Disease  
2025;
17
(3)
:1723-1735
.

Review Article

Quantitative CT evaluation of extrapulmonary lesions in chronic obstructive pulmonary disease: a narrative review
Chengyu Miao, Shengchuan Feng, Fengyan Wang, Zizheng Chen, Jiaxuan Xu, Xueping Li, Zifei Zhou, Rongchang Chen, Zhenyu Liang
Journal of Thoracic Disease  
2025;
17
(3)
:1736-1745
.
Lung cancer in young individuals; risk factors and epidemiology
Ryusuke Sumiya, Takeshi Matsunaga, Kenji Suzuki
Journal of Thoracic Disease  
2025;
17
(3)
:1746-1754
.

Surgical Technique

Mastering efficient Cor-Knot skills: novel S technique for solo automated suture fastening
June Lee, Hyun Song, Yang Gi Ryu, Kyoung Shik Narm
Journal of Thoracic Disease  
2025;
17
(3)
:1755-1759
.
The sandwich technique used for retrieving embolized catheter fragment dislodged in the pulmonary artery
Xiaolong Zhang, Zhichao Jiang, Youwei Xie, Xiaoming Ding, Jiecheng Zhang, Wenjun Zhao, Xiangzheng You, Guang Chen
Journal of Thoracic Disease  
2025;
17
(3)
:1760-1767
.

Editorial Commentary

Is segmentectomy a viable option for small-sized peripheral non-small-cell lung cancer?
Benjamin Bottet, Jean-Marc Baste
Journal of Thoracic Disease  
2025;
17
(3)
:1768-1770
.
When to initiate durvalumab after concurrent chemoradiation in unresectable stage III non-small cell lung cancer?—A commentary on the phase II TORG 1937 (DATE) study
Megan Smith-Uffen, Raman Sambhi, Saurav Verma, Daniel Breadner, Jacques Raphael
Journal of Thoracic Disease  
2025;
17
(3)
:1771-1776
.
Summary of the ROMIO randomized-control trial comparing clinical, economic and patient-reported outcomes between open versus hybrid esophagectomy in the United Kingdom
Christina M. Stuart, Micaella R. Zubkov, Robert A. Meguid
Journal of Thoracic Disease  
2025;
17
(3)
:1777-1783
.

Editorial

Medicine’s J.A.R.V.I.S. moment: how DeepSeek-R1 transforms clinical practice
Runchen Wang, Jianxing He, Hengrui Liang
Journal of Thoracic Disease  
2025;
17
(3)
:1784-1787
.