Vol 17, No 4 (April 30, 2025): Journal of Thoracic Disease

Editorial Commentary

Prospects of immune checkpoint inhibitor in combination with chemotherapy or chemoradiation in esophago-gastric cancers
Takeo Fujita, Daisuke Kajiyama, Yuto Kubo, Kazuma Sato
Journal of Thoracic Disease  
2025;
17
(4)
:1790-1794
.
Insights and considerations in the use of biologics for managing eosinophilic exacerbations in asthma and chronic obstructive pulmonary disease
Sang Hyuk Kim, Youlim Kim, Ji-Yong Moon, Kyung Hoon Min, Hyun Lee
Journal of Thoracic Disease  
2025;
17
(4)
:1795-1797
.
Complexity in aortic arch surgery and laws of diminishing return
Jeffrey Shuhaiber
Journal of Thoracic Disease  
2025;
17
(4)
:1798-1801
.
Novel neoadjuvant immunotherapy treatment and surveillance strategies in resectable esophageal cancer: innovation leads to improved outcomes
Kenneth M. Williams, Kian C. Banks, Jeffrey B. Velotta
Journal of Thoracic Disease  
2025;
17
(4)
:1802-1806
.

Expert Consensus

The management of type 2 inflammatory respiratory diseases: a Chinese expert consensus [2024]
Nan Jia, Meiling Jin, Yun Liu, Nan Su, Ying Sun, Wei Tang, Gang Wang, Hua Xie, Jiaxing Xie, Min Xie, Xin Yao, Huanping Zhang, Ruchong Chen, Chuntao Liu, Jing Li; on behalf of Respiratory Allergy Disease Group, the Chinese Allergy Society
Journal of Thoracic Disease  
2025;
17
(4)
:1807-1831
.
North American expert consensus on the clinical role of ex vivo lung perfusion (EVLP) with acellular perfusate
Matthew Bacchetta, Christian A. Bermudez, Ankit Bharat, A. Whitney Brown, Marie M. Budev, Marcelo Cypel, Caitlin T. Demarest, Daniel F. Dilling, Bartley P. Griffith, John C. Haney, Shaf Keshavjee, Zachary N. Kon, Tiago N. Machuca, Jorge M. Mallea, Si M. Pham, Thomas K. Waddell, Bryan A. Whitson, Kenneth R. McCurry
Journal of Thoracic Disease  
2025;
17
(4)
:1832-1843
.
Expert consensus on cancer treatment-related lung injury
Xinqing Lin, Hui Guo, Wei Zhao, Min Li, Gen Lin, Qian Chu, Enguo Chen, Liang’an Chen, Rui Chen, Tianqing Chu, Haiyi Deng, Yu Deng, Hangming Dong, Wen Dong, Yuchao Dong, Wenfeng Fang, Xin Gan, Liang Gong, Yingying Gu, Qian Han, Yue Hao, Yong He, Chengping Hu, Jie Hu, Yi Hu, Yongliang Jiang, Yang Jin, Fen Lan, Weimin Li, Weifeng Li, Wenhua Liang, Anwen Liu, Dan Liu, Ming Liu, Mengjie Liu, Zhuo Liu, Zhefeng Liu, Qun Luo, Liyun Miao, Chuanyong Mu, Pinhua Pan, Ping Peng, Jianwen Qin, Yinyin Qin, Panxiao Shen, Minhua Shi, Yong Song, Chunxia Su, Jin Su, Xin Su, Xiaowu Tan, Kejing Tang, Xiaomei Tang, Panwen Tian, Binchao Wang, Huijuan Wang, Kai Wang, Mengzhao Wang, Qi Wang, Wenxian Wang, Zhijie Wang, Di Wu, Fei Xu, Yan Xu, Chunwei Xu, Zhanhong Xie, Xiaohong Xie, Boyan Yang, Meng Yang, Feng Ye, Xiaoqun Ye, Zongyang Yu, Jian Zhang, Jianqing Zhang, Xiaoju Zhang, Fei Zhao, Xiaobin Zheng, Bo Zhu, Zhengfei Zhu, Jianya Zhou, Jianying Zhou, Min Zhou, Qing Zhou, Zihua Zou, Biniam Kidane, Elena Bignami, Fumio Sakamaki, Giandomenico Roviello, Hirokazu Taniguchi, Kyeongman Jeon, Lenko Saric, Miguel Ariza-Prota, Ninh M. La-Beck, Nobuhiro Kanaji, Satoshi Watanabe, Takehito Shukuya, Tomohiro Akaba, Tracy L. Leong, Wolfgang Gesierich, Yasuhiko Koga, Yoshinori Tanino, Yuji Uehara, Shiyue Li, Rongchang Chen, Chengzhi Zhou
Journal of Thoracic Disease  
2025;
17
(4)
:1844-1875
.

Original Article

Computed tomography-guided percutaneous biopsy for diagnosing pulmonary nodules: a prospective, multicenter observational study
Yun Liu, Ling Zhao, Hua-Long Yu, Wei Zhao, Dong Li, Guo-Dong Li, Hao Wang, Bin Huo, Qi-Ming Huang, Bai-Wu Liang, Rong Ding, Zhe Wang, Chen Liu, Liang-Yu Deng, Jun-Ru Xiong, Xue-Quan Huang, Chuang He
Journal of Thoracic Disease  
2025;
17
(4)
:1876-1887
.
Defining lung adenocarcinoma subtypes with glucocorticoid-related genes and constructing a prognostic index for immunotherapy guidance
Hongguang Tang, Jianhua Zhu, Yongliang Wang, Jianjie Zhang, Jianwei Zhou, Zhoumiao Chen
Journal of Thoracic Disease  
2025;
17
(4)
:1888-1905
.
The impact of true lumen morphology on frozen elephant trunk technique in chronic aortic dissection
Shinji Kanemitsu, Makoto Taniwaki, Renta Ishikawa, Shunsuke Sakamoto, Toru Mizumoto
Journal of Thoracic Disease  
2025;
17
(4)
:1906-1918
.
Combination of radiotherapy and immunochemotherapy improves survival outcomes in non-small cell lung cancer patients with liver metastasis
Dingqin Cai, Fenglin Lin, Lijiao Xie, Linpeng Zheng, Longyao Zhang, Lingchen Li, Yaxian Qi, Lingyou Sun, Chenrui Yin, Lvjun Yan, Xiaoyan Shi, Qiao Yang, Yi Zhou, Jianguo Sun
Journal of Thoracic Disease  
2025;
17
(4)
:1919-1933
.
Influence of clinical severity and ventilation time on the use of timed inspiratory effort (TIE) as a predictor of success in ventilatory weaning
Lilian Elisabete Bernardes Delazari, Lígia dos Santos Roceto Ratti, Adria Cristina da Silva, Melissa Sibinelli, Rodrigo Marques Tonella, Larissa Olivato, Beatriz Bueno dos Santos, Antonio Luís Eiras Falcão
Journal of Thoracic Disease  
2025;
17
(4)
:1934-1941
.
A prognostic nomogram based on lymph node skipping metastases in esophageal squamous cell carcinoma
Wen-Hui Hou, Li Jie, Liao Yao, Yu-Wei Yang, He Fang, Yuan-Yuan Zhao, Xian-Yan Chen, You-Ling Gong, Xiao-Bo Du
Journal of Thoracic Disease  
2025;
17
(4)
:1942-1957
.
Retrospective analysis of the sensitivity of reporting of thoracic computed tomography for pleural malignancy: an Australian multi-centre study
Simon C. Graffen, Louis C. T. Yeung, Jake Ball, Krishoban Baskaran, Reid Schofield, David J. Arnold, Christopher L. Grainge, Scott H. Twaddell, Michael W. Hayes, Najib M. Rahman, Vineeth George
Journal of Thoracic Disease  
2025;
17
(4)
:1958-1966
.
Physical activity after video-assisted thoracoscopic lung resection following an enhanced recovery after surgery-based protocol: first data from a prospective observational study
Christian Galata, Melanie Frey, Bernhard Gohrbandt, Eric Dominic Roessner, Ioannis Karampinis
Journal of Thoracic Disease  
2025;
17
(4)
:1967-1976
.
Analysis of risk factors and development of predictive model for acute myocardial injury in patients with acute exacerbation of chronic obstructive pulmonary disease
Shan Qi, Xuhong Li, Ying Jiang, Taiwen Zhu, Li Ze, Zhile Li, Wei Wang
Journal of Thoracic Disease  
2025;
17
(4)
:1977-1990
.
Pleural invasion of peripheral cT1 lung cancer by deep learning analysis of thoracoscopic images: a retrospective pilot study
Kohei Hashimoto, Calvin Davey, Kenshiro Omura, Satoru Tamagawa, Takafumi Urabe, Junji Ichinose, Yosuke Matsuura, Masayuki Nakao, Sakae Okumura, Hironori Ninomiya, Jun Sese, Mingyon Mun
Journal of Thoracic Disease  
2025;
17
(4)
:1991-1999
.
The role of postoperative radiotherapy for invasive thymic epithelial tumors: a single-center experience
Peng Zhang, Yongjia Chai, Peng Zhang
Journal of Thoracic Disease  
2025;
17
(4)
:2000-2013
.
A bibliometric analysis of malignant pleural mesothelioma from 2010 to 2023
Sheng Chen, Ce Zhao, Ruiqi Liu, Wenjie Jiao
Journal of Thoracic Disease  
2025;
17
(4)
:2014-2027
.
Nalmefene effectively relieves thoracic epidural opioid-induced pruritus without affecting analgesia: a randomized controlled clinical trial
Guiting Li, Huan Yan, Weishan Li, Ailun Li, Yiqi Zhu, Jiapeng Huang, Jing Cang, Fang Fang
Journal of Thoracic Disease  
2025;
17
(4)
:2028-2037
.
Serum IgA levels and survival in patients with idiopathic pulmonary fibrosis: association with serum cytokine levels and peripheral monocyte counts
Toru Arai, Masaki Hirose, Kazuyoshi Hatsuda, Tomoko Kagawa
Journal of Thoracic Disease  
2025;
17
(4)
:2038-2049
.
Achieving high patient satisfaction after sympathectomy through preoperative thoracoscopic sympathetic nerve block in primary hyperhidrosis
Ga Young Yoo, Jin Yong Jeong, June Lee, Jae Hoo Park, Jiwon Kang
Journal of Thoracic Disease  
2025;
17
(4)
:2050-2055
.
Photodynamic therapy as a promising treatment for long-segment and whole-circumferential early esophageal cancer
Lin Yuan, Ruijin Zhang, Jie Hua, Guoxin Zhang, Xinmin Si, Weifeng Zhang, Jinliang Ni, Xueliang Li
Journal of Thoracic Disease  
2025;
17
(4)
:2056-2066
.
Effect of OK-432 pleurodesis on long-term survival outcomes after pulmonary lobectomy for lung cancer patients: a retrospective case-control study
Hisashi Oishi, Ken Onodera, Hirotsugu Notsuda, Tatsuaki Watanabe, Yui Watanabe, Takaya Suzuki, Takeo Togo, Sakiko Kumata, Yoshinori Okada
Journal of Thoracic Disease  
2025;
17
(4)
:2067-2077
.
Midterm outcomes of concomitant ascending aorta replacement with rapid deployment aortic valve replacement
Sangil Yun, Kyung Hwan Kim, Suk Ho Sohn, Yongwoo Chung, Yoonjin Kang, Ji Seong Kim, Jae Woong Choi
Journal of Thoracic Disease  
2025;
17
(4)
:2078-2090
.
The use of postoperative X-ray to evaluate residual pleural space and predict infectious pleuropulmonary complications after lung resection for infectious disease
Eserval Rocha Jr, Flavia Alves Corrêa de Queiroz, Jaqueline Schaparini Fonini, João Marcelo Lopes Toscano de Brito, Alessandro Wasum Mariani, Ricardo Mingarini Terra, Paulo Manuel Pêgo-Fernandes
Journal of Thoracic Disease  
2025;
17
(4)
:2091-2100
.
Randomized study assessing the effectiveness and safety of a novel scoring balloon for percutaneous coronary intervention: the Wedge NC trial
Haibo Chen, Jian Xu, Delong Chen, Feng Gao, Yabin Liu, Hanbin Cui, Jingfeng Wang, Suxia Guo, Zhimin Du, Jinyu Huang, Xingwei Zhang, Wenbing Jiang, Zhenfeng Cheng, Jun Jiang
Journal of Thoracic Disease  
2025;
17
(4)
:2101-2112
.
Prognosis and relapse patterns in patients with non-small cell lung cancer with pathologic complete response after neoadjuvant immunochemotherapy
Yifan Fang, Wanpu Yan, Ze-Rui Zhao, Long Jiang, Xiangyang Yu, Xin Yang, Zhentao Yu, Qingquan Luo, Hao Long, Ke-Neng Chen
Journal of Thoracic Disease  
2025;
17
(4)
:2113-2125
.
Relationship between perioperative plasma neutrophil gelatinase-associated lipocalin level and acute kidney injury after acute type A aortic dissection
Rutao Guo, Suwei Chen, Yipeng Ge, Yongliang Zhong, Chengnan Li, Zhiyu Qiao, Haiou Hu, Junming Zhu
Journal of Thoracic Disease  
2025;
17
(4)
:2126-2139
.
Biocompatibility of a novel lung sealant based on functionalized polyoxazolines in an ovine model of parenchymal lung injury
Bob P. Hermans, Shoko Vos, Wilson W. L. Li, Erik H. F. M. van der Heijden, Harry van Goor, Ad F. T. M. Verhagen, Richard P. G. ten Broek
Journal of Thoracic Disease  
2025;
17
(4)
:2140-2158
.
Application of novel dark-quencher labeled probes in multiplex qRT-PCR assays for rapid detection of SARS-CoV-2 variants
Zhiqi Zeng, Jie Yang, Jun Dai, Lirong Zou, Zhengshi Lin, Yong Liu, Wenda Guan, Feng Li, Kui Zheng, Shuai Yuan, Fangfang Sun, Fengxia He, Ye Hong, Hui Li, Wei Liu, Guangqi Men, Xinyue Zhang, Yun Lan, Xizi Deng, Liya Li, Yaqing Lin, Honghao Lai, Peng Qian, Qinghong Fan, Mengling Jiang, Jiaojiao Li, Guofang Tang, Qiaohui Mo, Xiaoyan Deng, Jicheng Huang, Xiaoling Deng, Zifeng Yang
Journal of Thoracic Disease  
2025;
17
(4)
:2159-2173
.
Comparison of robot-assisted and video-assisted thoracic sleeve lobectomy in non-small cell lung cancer: insights from a high-volume center
Shiqi Hu, Xiaoping Zeng, Shiyue Wan, Suyu Wang, Qianxin Zhou, Ziyun Shen, Jing Zhang, Peng Zhang
Journal of Thoracic Disease  
2025;
17
(4)
:2174-2185
.
Single-use flexible bronchoscope evaluation for bronchoalveolar lavage
Ajay Wagh, David Hoffman, Christina Cool, Audra Schwalk
Journal of Thoracic Disease  
2025;
17
(4)
:2186-2193
.
Early versus late chest tube removal after surgery for primary spontaneous pneumothorax—a systematic review and meta-analysis
Quirine C. A. van Steenwijk, Louisa N. Spaans, Jerry Braun, Marcel G. W. Dijkgraaf, Frank J. C. van den Broek
Journal of Thoracic Disease  
2025;
17
(4)
:2194-2205
.
Establishment of a prognostic nomogram for evaluating non-adjuvant therapy in patients with stage I to III esophageal cancer: a population-based study
Guanglei Zhang, Yan Zhang, Shu Chen, Hang Guo, Xiao Qi, Baofeng Li, Jincheng Wang, Chunguang Wang
Journal of Thoracic Disease  
2025;
17
(4)
:2206-2216
.
miR-124/PTBP1/PKM axis modulates pulmonary artery endothelial metabolism in a pulmonary thromboembolism rat model
Min-Xia Yang, Zhi-Zhu Wu, Da-Wen Wu, Xiu-Yu Liao, Qiu-Xia Wu, Nan Shao, Chao-Sheng Deng
Journal of Thoracic Disease  
2025;
17
(4)
:2217-2226
.
Comparison of prognoses of patients with type A aortic dissection treated with surgery in acute, subacute and chronic phases
Zhiqi Ji, Jinzhang Li, Xiaohan Zhong, He Sang, Wenjian Jiang, Hongjia Zhang
Journal of Thoracic Disease  
2025;
17
(4)
:2227-2238
.
Prognostic role of subsolid ground-glass opacity, pure ground-glass opacity, and solid nodules of the lung: a retrospective observational study
Lorenzo Federico Zini Radaelli, Elisabetta Fabbri, Matteo Costantini, Michele Gaudio, Alessandra Dubini, Emanuela Giampalma, Franco Stella, Beatrice Aramini
Journal of Thoracic Disease  
2025;
17
(4)
:2239-2247
.
Implications of surgical intervention in patients with metastatic pulmonary carcinoid tumors: a SEER-based population study and propensity score matching comparative analysis
Chenxu Liu, Zhuangzhuang Cong, Jing Luo, Qin Wang, Yong Qiang, Haiwei Wu, Yi Shen
Journal of Thoracic Disease  
2025;
17
(4)
:2248-2264
.
Efficacy of Amplatzer device for endobronchial treatment of hemoptysis: case series
Lev Freidkin, Ramzi Zamaereh, Shimon Izhakian, Dror Rosengarten, Barak Pertzov, Shai M. Amor, Alex Krolik, Moshe Heching, Mordechai R. Kramer
Journal of Thoracic Disease  
2025;
17
(4)
:2265-2272
.
Neoadjuvant arterial infusion chemotherapy combined with immunotherapy in treating locally advanced lower esophageal and esophagogastric junction cancer
Qingjie Yang, Shenghua Lv, Qingtian Li, Linhui Lan, Ningquan Liu, Mingyang Wang, Xiaoyan Sun, Xinhai Feng, Kaibao Han
Journal of Thoracic Disease  
2025;
17
(4)
:2273-2285
.
Computed tomography imaging features in Stanford type-A aortic dissection predict in-hospital rupture
Jia-Rong Ma, Pian-Pian Yan, Sheng-Wen Guo, Xi-Jie Wu
Journal of Thoracic Disease  
2025;
17
(4)
:2286-2294
.
Impact of biopsy number and radiologic pattern on diagnostic yield and complications of transbronchial lung cryobiopsy in interstitial lung diseases: a multi-center retrospective study
Ranxun Chen, Lulu Chen, Hui Ge, Qingqing Xu, Qi Zhao, Yingwei Zhang, Fanqing Meng, Hourong Cai, Shuhong Guan, Chong Li, Lingfeng Min, Bi Chen, Jinghong Dai
Journal of Thoracic Disease  
2025;
17
(4)
:2295-2305
.
Tumor peripheral bronchial signature predicts spread through air spaces in resected invasive mucinous adenocarcinoma of the lung
Xilin Hu, Jing Guo, Jiaheng Zhang, Weijun Zhao, Wentao Hu, Jun Yang
Journal of Thoracic Disease  
2025;
17
(4)
:2306-2320
.
Single-cell analysis and machine learning-based integration develop an immune-responsive signature of antigen-presenting cancer-associated fibroblasts in lung adenocarcinoma
Weijiao Xu, Haitang Yang, Feng Yao
Journal of Thoracic Disease  
2025;
17
(4)
:2321-2338
.
Diagnostic accuracy of interleukin 32γ for tuberculous pleural effusion
Qi Wang, Li Ma, Kan Zhai, Feng-Shuang Yi, Huan-Zhong Shi, Ming-Ming Shao
Journal of Thoracic Disease  
2025;
17
(4)
:2339-2349
.
Increasing S1P promotes M1 macrophage in chronic obstructive pulmonary disease and chronic obstructive pulmonary disease-obstructive sleep apnea overlap syndrome via S1PR1/HDAC1 signaling
Ruoxuan Hei, Xiuping Wu, Tongtong Zhang, Min Zhang, Yue Huang, Zhou Zhou, Wendi Xiao, Wen Ai, Yanwei Chen
Journal of Thoracic Disease  
2025;
17
(4)
:2350-2364
.
Prognostic indicators and nomograms for postoperative survival among younger patients with non-small cell lung cancer
Yi Liu, Qirui Chen, Zhirong Zhang, Huandong Huo, Takuya Watanabe, Shuo Chen, Bin Hu
Journal of Thoracic Disease  
2025;
17
(4)
:2365-2376
.
Causal relationship between serum metalloproteinase 12 levels and aortic dissection and aortic aneurysm: a bidirectional Mendelian randomization study
Xiaoyan Feng, Shoulei Chen, Tao Liu, Hexi Huang, Giovanni Mariscalco, Carlos A. Mestres, Marcus Taylor, Ken Nakamura, Baoshi Zheng
Journal of Thoracic Disease  
2025;
17
(4)
:2377-2385
.
Three key factors predicting the severity of exacerbations of chronic obstructive pulmonary disease: T lymphocytes, lactate, and prealbumin
Haijun Wang, Peter S. P. Cho, Vasileios Kouritas, Lanfang Feng
Journal of Thoracic Disease  
2025;
17
(4)
:2386-2393
.
Comparison of clinicopathologic features and prognosis between surgically resected pulmonary large-cell neuroendocrine carcinoma and small-cell lung cancer
Yuke Mao, Hao Chang, Lu Wang, Jinlong Teng, Tianjun Li, Luca Ampollini, Yoshinobu Ichiki, Robert A. Ramirez, Hong Liu, Baohui Han, Jing Wang, Yanan Wang
Journal of Thoracic Disease  
2025;
17
(4)
:2394-2410
.
The effects of different prone ventilation strategies on mechanical power and respiratory mechanics in acute respiratory distress syndrome patients: a prospective, single-center observational study
Pei Hong, Yuequn Chen, Junli Xia, Salim Surani, Yexing Dai, Junhong Zhu
Journal of Thoracic Disease  
2025;
17
(4)
:2411-2422
.
Machine learning algorithms for predicting malignancy grades of lung adenocarcinoma and guiding treatments: CT radiomics-based comparisons
Jun Zhu, Jiayu Tao, Fengfeng Zhang, Jie Yao, Ke Chen, Yuxuan Wang, Xiaochen Lu, Bin Ni, Maoshan Zhu
Journal of Thoracic Disease  
2025;
17
(4)
:2423-2440
.
Computed tomography-based body composition and systemic inflammation for outcome prediction in patients with resectable esophageal squamous cell carcinoma
Rong Wang, Liyang Zhu, Jiqing Hao, Nathawadee Lerttanatum, Xiangxun Chen, Liming Wu, Yichun Wang
Journal of Thoracic Disease  
2025;
17
(4)
:2441-2452
.
Association between reactive cutaneous capillary endothelial proliferation and the efficacy of camrelizumab in esophageal cancer: a retrospective cohort study
Yuzi Qiu, Gelan Su, Lan Zhang, Haiyan Fan, Huijin Zhao, Chunyan Wang, Lulu Liu, Bo Chen, Xiaoming Li, Shengmian Li
Journal of Thoracic Disease  
2025;
17
(4)
:2453-2472
.
An integrated analysis of scRNA-seq and RNA-seq data revealed metastasis-related regulators as prognostic indicators in lung adenocarcinoma
Yang Jiang, Danrong Ye, Yongxin Zhou
Journal of Thoracic Disease  
2025;
17
(4)
:2473-2491
.
Correlation analysis of hematocrit level and coronary heart disease in patients with chest pain: a case-control study
Jiahong Xie, Hongshuai Cao, Dongxu Jin, Yuxin Wang, Xiaolu Li, Matthew Budoff, Hongfeng Jiang, Jingyi Ren
Journal of Thoracic Disease  
2025;
17
(4)
:2492-2502
.
Computed tomography characteristics of chronic bronchitis and its association with disease severity and clinical outcomes in viral pneumonia: a retrospective cohort study
Xiaofei Wang, Zhentao Zhou, Yuting Peng, Yinying Tang, Qi Dai, Jianjun Zheng, Jingfeng Zhang
Journal of Thoracic Disease  
2025;
17
(4)
:2503-2518
.
Machine learning-based model for the prediction of acute kidney injury following coronary artery bypass graft surgery in elderly Chinese patients
Haiming Li, Hui Hu, Jingxing Li, Wenxing Peng
Journal of Thoracic Disease  
2025;
17
(4)
:2519-2527
.
Clinical analysis of incidental discovery of pulmonary nodules with computed tomography: a retrospective cohort study
Peilong Zhang, Bohua Wei, Gaojun Lu, Yi Zhang
Journal of Thoracic Disease  
2025;
17
(4)
:2528-2536
.
A bibliometric analysis of the literature published on autophagy, ferroptosis, necroptosis, and pyroptosis in cardiovascular disease from 2009 to 2023
Yan Zhang, Tianyi Long, Bo Wei, Huan Zhou, Xinhai Yin, Zhangrong Chen, Pietro Di Fazio, Wei Li, Haiyan Zhou
Journal of Thoracic Disease  
2025;
17
(4)
:2537-2562
.
Pre-percutaneous coronary intervention hemoglobin as a prognostic indicator for 6-month mortality in acute myocardial infarction patients: a secondary analysis of the Korea Acute Myocardial Infarction Registry National Institutes of Health cohort
Tianyi Long, Chao Li, Bing Wang, Yan Zhang, Huan Zhou, Bo Wei, Xingde Liu, Wei Li, Haiyan Zhou
Journal of Thoracic Disease  
2025;
17
(4)
:2563-2575
.
Identification of potential therapeutic drug targets for sepsis by combining the human plasma proteome and genome: a Mendelian randomization study
Wenyu Zhou, Zhi Lin, Huimin Deng, Tian Jin, Li Zheng, Yuanli Chen, Hao Yang, Xin Lv
Journal of Thoracic Disease  
2025;
17
(4)
:2576-2593
.
Single versus multisite intercostal nerve block for post-thoracoscopic pain: a prospective observational study
Bixin Wen, Jinling Yao, Shilong Wang, Binhao Xu, Yuanjing Zhang, Wen Wang, Qiaochu Xu, Li Li, Changhong Liu, Yaqing Huang, Satoshi Hanada, Min Wang, Yuhui Shi, Zhenrong Zhang, Chaoyang Liang, Yajun Zhang, Ying Chen, Yang Yang, Qianli Ma
Journal of Thoracic Disease  
2025;
17
(4)
:2594-2604
.
Construction of a multigenic diagnostic, prognostic, and immune infiltration model with methylation-associated regulators in esophageal squamous cell carcinoma
Xing Liu, Feng Shen, Ting Wang, Jingru Li, Xiaowei Sheng, Yulan Deng, Xuewei Zhang, Bing Zhao, Ying Zhou, Peng Shang, Xinyi Shi, Zilong Zhao, Zhonglin Yu, Sarbajit Mukherjee, Anwaar Saeed, Jing Liu
Journal of Thoracic Disease  
2025;
17
(4)
:2605-2622
.

Study Protocol

Preventive effect of Lianhua Qingwen capsule on close contacts of seasonal influenza in residential environments: protocol for a multicenter, randomized, double-blind, placebo-controlled study
Yangqing Zhan, Zhonghao Fang, Yinhong Hu, Jincan Luo, Lili Hou, Yilin Li, Qiexinhao Li, Yuyue Liu, Chuoqi Yang, Shiwei Liang, Kun Zhao, Nanshan Zhong, Zifeng Yang
Journal of Thoracic Disease  
2025;
17
(4)
:2623-2633
.
Active surveillance for patients with multifocal ground-glass nodules: protocol of a prospective, multi-center, single-arm trial (ECTOP-1021)
Haoxuan Wu, Penghao Deng, Fangqiu Fu, Yang Zhang, Haiquan Chen; on behalf of the Eastern Cooperative Thoracic Oncology Project (ECTOP) study group
Journal of Thoracic Disease  
2025;
17
(4)
:2634-2639
.

Review Article

Phenotypes and endotypes in bronchiectasis: a narrative review of progress toward precision medicine
Hayoung Choi, Yong-Hua Gao
Journal of Thoracic Disease  
2025;
17
(4)
:2640-2654
.
Ketamine administration for rigid bronchoscopy in adult: literary review and the operator perception
Giovanni Tacchi, Luca Frasca, Filippo Longo, Antonio Sarubbi, Valentina Marziali, Ilaria Suriano, Fabio Costa, Pierfilippo Crucitti
Journal of Thoracic Disease  
2025;
17
(4)
:2655-2661
.
Infective endocarditis risk scores: a narrative review
Cindy Sun-Yan Cho, Kevin Lim, Ivan Chi-Hin Siu, Jacky Yan-Kit Ho, Simon Chi-Ying Chow, Takuya Fujikawa, Micky Wai-Ting Kwok, Randolph Hung-Leung Wong
Journal of Thoracic Disease  
2025;
17
(4)
:2662-2678
.
mTOR and autophagy in acute lung injury pathogenesis and therapeutic potential
Zihan Yi, Jiahao Liu, Lanying Shen, Yue Hu
Journal of Thoracic Disease  
2025;
17
(4)
:2679-2692
.

Surgical Technique

Initial experience of complete portal robotic esophagectomy for esophageal carcinoma in semi-prone position under single-lumen insertion for anaesthesia
Mu-Zi Yang, Zi-Hui Tan, Yuan-Yuan Zhang, Wei Gan, Chu-Long Xie, Tian-Yu Sun, Hao-Xian Yang
Journal of Thoracic Disease  
2025;
17
(4)
:2693-2704
.
Single venous cannulation for bi-atrial venoarterial extracorporeal membrane oxygenation in bridge to transplantation: a two-in-one approach
Chadi Aludaat, Maud-Emmanuelle Olivier, Nathalie Nardone, Lisa Omouri, Vincent Le Guillou, Catherine Nafeh-Bizet, Arnaud Gay, Jean-Marc Baste, Emmanuel Besnier, Fabrice Bauer
Journal of Thoracic Disease  
2025;
17
(4)
:2705-2717
.
New standardized five-zone lobectomy with structured assessment in robotic surgery: the French lobectomy
Gerardo Mordojovich, Niek Hugen, Benjamin Bottet, François Montagne, Ilies Bouabdallah, Pierre-Benoît Pagès, Mathieu Sarsam, Pascal Alexandre Thomas, Jean-Marc Baste
Journal of Thoracic Disease  
2025;
17
(4)
:2718-2729
.

Case Report: iMDT Corner

SMARCA4-deficient undifferentiated thoracic tumor: a case report and literature review
Zhenzhen Liu, Na Li, Jiaqiu Liu, Jielin Li, Jingfei Sun, Franz Zehentmayr, Igor Gomez-Randulfe, Yuan Liang
Journal of Thoracic Disease  
2025;
17
(4)
:2730-2740
.

Letter to the Editor

COVID-19 and anticoagulation: evidence from a meta-analysis of randomized controlled trials
Yanan Zhou, Yanping Yang, Ying Wang, Dongni Hou, Yuanlin Song
Journal of Thoracic Disease  
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