Vol 15, No 9 (September 28, 2023) - Journal of Thoracic Disease

Nicky Janssen, Aimée J. P. M. Franssen, Jean H. T. Daemen, Lori M. van Roozendaal, Karel W. E. Hulsewé, Yvonne L. J. Vissers, Dawn E. Jaroszewski, Erik R. de Loos

PDF Pages: 4573-4576 Full Text (534) COI Form Open Access

Original Article

Utility of multimodal sampling and testing during advanced bronchoscopy for diagnosing atypical respiratory infections in a Coccidioides-endemic region

Ara A. Chrissian, Sevwandi De Silva, Michele Quan, Erin Wiltchik, Pranjal Patel, Brian Furukawa, Daniel Rogstad, Nicholas Rockwood, Elliot Ho, Gregory Cheek

PDF Pages: 4577-4595 Full Text (680) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

A modified prosthesis eversion technique for proximal anastomosis in ascending aorta replacement

Hua-Jie Zheng, Xian-Pu Zhang, San-Jiu Yu, De-Qing Lin, Yong-Bo Cheng, Chao-Jun Yan, Ping He, Jun Li, Wei Cheng

PDF Pages: 4596-4605 Full Text (951) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

PD-1 inhibitors-associated myocarditis in non-small cell lung cancer patients

Yuwen He, Wanwen Chen, Junying Cai, Caiyin Luo, Chengzhi Zhou, Li Wei

PDF Pages: 4606-4619 Full Text (1168) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Expression of EGFR-mutant proteins and genomic evolution in EGFR-mutant transformed small cell lung cancer

Shi-Ling Zhang, Chan-Yuan Zhang, Yu-Qing Chen, Yu-Fa Li, Zhi Xie, Xu-Chao Zhang, Qing Zhou, Wen-Zhao Zhong, Jie Huang, Hao Sun, Ming-Ying Zheng, Fa-Man Xiao, Hong-Hong Yan, Dan-Xia Lu, Zhi-Yi Lv, Yi-Long Wu, Hua-Jun Chen, Jin-Ji Yang

PDF Pages: 4620-4635 Full Text (1234) Reporting Checklist Data Sharing Statement COI Form Open Access

CyberKnife^® stereotactic radiation therapy for stage I lung cancer and pulmonary oligometastases: is fiducial implantation still relevant?—a cohort study

Victor Oudin, Julia Salleron, Vincent Marchesi, Didier Peiffert, Myriam Khadige, Jean-Christophe Faivre

PDF Pages: 4636-4647 Full Text (559) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Perioperative systemic magnesium sulfate minimizes the incidence of atrial fibrillation after thoracotomy for lung resection: a prospective observational study

Verena Ghezel-Ahmadi, David Ghezel-Ahmadi, Grietje Beck, Servet Bölükbas

PDF Pages: 4648-4656 Full Text (642) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

The essential role of non-steroidal anti-inflammatory drugs in pain control following robotic thoracoscopic lung resections

Daniel J. Gross, Karishma Kodia, Ahmed Alnajar, Nestor R. Villamizar, Dao M. Nguyen

PDF Pages: 4657-4667 Full Text (643) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Assessment of a collaborative treatment model for trimodal management of esophageal cancer

Brooks V. Udelsman, Theresa Ermer, Sora Ely, Maureen E. Canavan, Peter Zhan, Daniel J. Boffa, Justin D. Blasberg

PDF Pages: 4668-4680 Full Text (387) Reporting Checklist Peer Review File COI Form Open Access

Impact of sepsis on Eastern Cooperative Oncology Group performance status among fully ambulatory patients: a prospective nationwide multicenter cohort

Kyu Jin Lee, Ji Young Park, Kyeongman Jeon, Ryoung-Eun Ko, Gee Yong Suh, Sung Yun Lim, Yeon Joo Lee, Dong Kyu Oh, Mi-Hyeon Park, Chae-Man Lim, Sunghoon Park; On behalf of the Korean Sepsis Alliance (KSA) investigators

PDF Pages: 4681-4692 Full Text (638) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Systematic review and meta-analysis of time-to-event long-term outcomes following the Ross procedure

Junichi Shimamura, Shinichi Fukuhara, Yujiro Yokoyama, Hisato Takagi, Maral Ouzounian, Toshiki Kuno

PDF Pages: 4693-4702 Full Text (585) Reporting Checklist Peer Review File COI Form Open Access

Intrinsic pulmonary sealing, its mechanisms and impact on validity and translational value of lung sealant studies: a pooled analysis of animal studies

Bob P. Hermans, Wilson W. L. Li, Edwin A. Roozen, Daniël I. M. van Dort, Shoko Vos, Stefan M. van der Heide, Erik H. F. M. van der Heijden, Richard P. G. ten Broek, Harry van Goor, Ad F. T. M. Verhagen

PDF Pages: 4703-4716 Full Text (Video) (473) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Prevention of contamination after endotracheal intubation using a dedicated sleeve

Alejandro Pino, Justin J. Lee, Nazish K. Hashmi, Amanda Brucker, Shein-Chung Chow, Kamran Mahmood

PDF Pages: 4717-4724 Full Text (488) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

The long-term impact of COVID-19 pneumonia on pulmonary function and exercise capacity

Warawut Chaiwong, Athavudh Deesomchok, Chaicharn Pothirat, Chalerm Liwsrisakun, Pilaiporn Duangjit, Chaiwat Bumroongkit, Theerakorn Theerakittikul, Atikun Limsukon, Pattraporn Tajarernmuang, Konlawij Trongtrakul, Nutchanok Niyatiwatchanchai

PDF Pages: 4725-4735 Full Text (1051) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

New method for delineation of the intersegmental line in a deflated lung

Shoji Okado, Yuka Kadomatsu, Megumi Nakao, Harushi Ueno, Koichi Fukumoto, Shota Nakamura, Toyofumi Fengshi Chen-Yoshikawa

PDF Pages: 4736-4744 Full Text (Video) (604) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Surgical outcomes of 500 robot-assisted minimally invasive esophagectomies for esophageal carcinoma

Yun-Ho Jeon, Jae Kwang Yun, Yong Ho Jeong, Chung-Sik Gong, Yoon Se Lee, Yong-Hee Kim

PDF Pages: 4745-4756 Full Text (519) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Black race and lower age at surgery are associated with smoking relapse in a safety-net setting after surgery for stage I non-small cell lung cancer

Aniket Vazirani, Adriana Rodriguez, Flaminio Pavesi, Shannon McDermott, Howard Cabral, Ehab Billatos, Kei Suzuki

PDF Pages: 4757-4764 Full Text (624) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Is preoperative intracranial hemorrhage a surgical contraindication in infective endocarditis with stroke?

June Lee, Hyun Ah Lim, Seok Beom Hong, Yong Han Kim, Hwan Wook Kim, Do Yeon Kim

PDF Pages: 4765-4774 Full Text (675) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Quantitative analyzes of the variability in airways via four-dimensional dynamic ventilation CT in patients with chronic obstructive pulmonary disease: correlation with spirometry data and severity of airflow limitation

Wei-Ting Hu, Wei Chen, Min Zhou, Jing Fan, Fuhua Yan, Bing Liu, Fang-Ying Lu, Rong Chen, Yi Guo, Wenjie Yang

PDF Pages: 4775-4786 Full Text (621) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

The impact of postoperative cerebrospinal fluid drainage on neurological improvement following thoracic aortic and thoracoabdominal aortic surgery

Tomohiro Nakajima, Yutaka Iba, Tsuyoshi Shibata, Shingo Tsushima, Ayaka Arihara, Itaru Hosaka, Akihito Okawa, Junji Nakazawa, Nobuyoshi Kawaharada

PDF Pages: 4787-4794 Full Text (504) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Prognostic significance of limited resection in pathologic stage I lung adenocarcinoma with spread through air spaces

Kuan Xu, Hanqing Huang, Qian Zhu, Tangbing Chen, Minjun Shi, Hong Yu, Bo Ye

PDF Pages: 4795-4807 Full Text (517) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Machine learning analysis of primary hyperhidrosis for classification of hyperhidrosis type and prediction of compensatory hyperhidrosis

Kwan Yong Hyun, Jae Jun Kim, Kyong Shil Im, Bong Sung Lee, Yun Ji Kim

PDF Pages: 4808-4817 Full Text (479) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Placental transmogrification of the lung: CT findings with pathologic correlation in six patients

Sang Hwa Shin, Yoon Ki Cha, Jong Hee Kim, Jung Han Woo, Tae Jung Kim, Myung Jin Chung, Joungho Han, Yun-Jung Lim

PDF Pages: 4818-4825 Full Text (568) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Comparison of self- and balloon-expandable valves in patients with dilatated ascending aorta undergoing transcatheter aortic valve replacement

Kang An, Fengwen Zhang, Wenbin Ouyang, Xiangbin Pan

PDF Pages: 4826-4835 Full Text (696) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Radiation dose of cone beam CT combined with shape sensing robotic assisted bronchoscopy for the evaluation of pulmonary lesions: an observational single center study

Kim Styrvoky, Audra Schwalk, David Pham, Kristine Madsen, Hsienchang T. Chiu, Muhanned Abu-Hijleh

PDF Pages: 4836-4848 Full Text (815) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Robotic chest wall resection for primary benign chest wall tumors and locally advanced lung cancer: an institutional case series and national report

Raymond A. Verm, Wickii T. Vigneswaran, Andrew Lin, Joseph Zywiciel, Richard Freeman, Zaid M. Abdelsattar

PDF Pages: 4849-4858 Full Text (Video) (554) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Nadir oxygen delivery during cardiopulmonary bypass in acute type A aortic dissection repair

Qinbao Peng, Minjia Cai, Xing Chen, Tianxiao Lin, Weipeng Meng, Li Guan, Peng Zhu, Shaoyi Zheng, Jun Lu, Pengyu Zhou

PDF Pages: 4859-4868 Full Text (445) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Impact of anesthetic factors on prognosis of patients with non-small cell lung cancer after surgery

Wenzhi Zhu, Shuang Li, Xinqiang Ji, Hongyu Tan

PDF Pages: 4869-4884 Full Text (510) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Yiqi Yangjing recipe stimulates apoptosis while suppressing the energy metabolism via under-expression of PFKFB3 in A549 cells

Yu-Han Wang, Qing-Ting Wang, Xiao-Ting Wu, Yun Dong, Qing Cui, Ya-Ning Zhou, Xi-Wen Yang, Wen-Feng Lu, Wan-Yu Li, Hui Wang, Xiao-Dong Zhao, Ming Zhang

PDF Pages: 4885-4895 Full Text (726) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

A predictive model for the identification of the risk of sepsis in patients with Gram-positive bacteria in the intensive care unit

Xiaohong Chen, Yufeng Zhou, Li Luo, Xiaojing Peng, Tao Xiang

PDF Pages: 4896-4913 Full Text (735) Reporting Checklist Peer Review File COI Form Open Access

Predictive value of serum β2-microglobulin in cardiac valve calcification in maintenance hemodialysis patients

Yan Shen, Jia-Jia Chen, Wu-Bin Yao, Su-Juan Feng, Hong-Li Yang, Dong-Mei Chen, Vimal Master Sankar Raj, Liang-Lan Shen, Hua-Xing Huang

PDF Pages: 4914-4924 Full Text (477) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Real-world effectiveness of azvudine for patients infected with the SARS-CoV-2 omicron subvariant BA.5 in an intensive care unit

Xiuping Qi, Yun Yang, Baoqiang Gong, Zhiwei Li, Dong Liang

PDF Pages: 4925-4937 Full Text (812) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

A new prognostic model of esophageal squamous cell carcinoma based on Cloud-least squares support vector machine

Ke Liu, Liu-Qing Shen, Dian-Bao Zhang, Yi-Xin Kang, Yi-Xuan Wang, Pan Chen, Ran Zhang, Bian-Li Gu, Ye-Lin Jiao, Xiang Yuan, Yi-Jun Qi, She-Gan Gao

PDF Pages: 4938-4948 Full Text (630) Reporting Checklist Peer Review File COI Form Open Access

Gene modules and genes associated with postoperative atrial fibrillation: weighted gene co-expression network analysis and circRNA-miRNA-mRNA regulatory network analysis

Xiaomeng Chen, Huaiguang Tang, Kongmiao Lu, Zhaozhuo Niu, Wei Sheng, Ho Young Hwang, Philip Y. K. Pang, Joseph D. Phillips, Ali Khoynezhad, Xiaolu Qu, Bingong Li, Wei Han

PDF Pages: 4949-4960 Full Text (857) Reporting Checklist Peer Review File COI Form Open Access

Surgical stabilization of multiple rib fractures in an Asian population: a systematic review and meta-analysis

Weiwei He, Yi Yang, Raymark Salonga, Ledford Powell, Patrick Greiffenstein, Jonne T. H. Prins, Stephen Patrick Abella

PDF Pages: 4961-4975 Full Text (875) Reporting Checklist Peer Review File COI Form Open Access

Diagnostic and treatment value of XPNPEP3 in acute myocardial infarction

Lunna Ai, Yuqi Liu, Yundai Chen

PDF Pages: 4976-4986 Full Text (626) Reporting Checklist Peer Review File COI Form Open Access

Time-course transcriptome analysis of lungs from mice infected with inhaled aerosolized Stenotrophomonas maltophilia

Guangyang Xu, Hui Liu, Dunling Xia, Yan Zhao, Yao Qian, Hongyan Han, Jiahua Pan, Hua Jiang, Yongqiang Jiang, Gengyun Sun

PDF Pages: 4987-5005 Full Text (849) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Cullin7 induces docetaxel resistance by regulating the protein level of the antiapoptotic protein Survivin in lung adenocarcinoma cells

Yumiao Li, Wenyi He, Xiangpeng Gao, Xiaomei Lu, Fangni Xie, Sang-Won Um, Min-Woong Kang, Hua Yang, Yanhong Shang, Zhiyu Wang, Jiejun Fu, Youchao Jia

PDF Pages: 5006-5019 Full Text (683) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Brief Report

Tumor-to-thoracic height ratio as an easy method to predict the feasibility of reduced-port video-assisted thoracic surgery for mediastinal lesions in children: a single-center experience

Haruhiko Shiiya, Kichizo Kaga, Hideki Ujiie, Aki Fujiwara-Kuroda, Jun Muto, Shunsuke Nomura, Shohei Honda, Tatsuya Kato

PDF Pages: 5020-5028 Full Text (357) Reporting Checklist Peer Review File COI Form Open Access

Case Series

Simultaneous surgical treatment of aortic coarctation and aortic root disease: a report of case series

Bo Yang, Xiaochun Duan, Huanyu Qiao, Yongmin Liu, Xiaona Wang, Wenxing Peng

PDF Pages: 5029-5036 Full Text (362) Reporting Checklist Peer Review File COI Form Open Access

Surgical Technique

FlatWire Sternal Closure System technique for median sternotomy closure

Audrey L. Khoury, Sapna Patel, Smith Ngeve, Kayla Doughty, Hadley K. Wilson, Thomas G. Caranasos

PDF Pages: 5037-5040 Full Text (Video) (678) Reporting Checklist Peer Review File COI Form Open Access

Review Article

Sex differences in coronary artery bypass graft surgery outcomes: a narrative review

Lamia Harik, Roberto Perezgrovas-Olaria, Giovanni Jr Soletti, Arnaldo Dimagli, Talal Alzghari, Kevin R. An, Gianmarco Cancelli, Mario Gaudino

PDF Pages: 5041-5054 Full Text (1153) Reporting Checklist Peer Review File COI Form Open Access

The growing impact of air quality on lung-related illness: a narrative review

Parnia Behinaein, Hollis Hutchings, Thomas Knapp, Ikenna C. Okereke

PDF Pages: 5055-5063 Full Text (1143) Reporting Checklist Peer Review File COI Form Open Access

Hyperthermic intrapleural chemotherapy: an update

Megan E. Campany, Pedro A. Reck dos Santos, Britton B. Donato, Cory M. Alwardt, Vinicius Ernani, Jonathan D’Cunha, Staci E. Beamer

PDF Pages: 5064-5073 Full Text (891) Peer Review File COI Form Open Access

Cardiac transplantation in adult congenital heart disease: a narrative review

Noy Meshulami, Pritik Shah, Shubhi Kaushik, Raghav Murthy

PDF Pages: 5074-5087 Full Text (1404) Reporting Checklist Peer Review File COI Form Open Access

Transesophageal endoscopic ultrasound with bronchoscope-guided fine-needle aspiration for diagnostic and staging purposes: a narrative review

Goohyeon Hong, Masahide Oki

PDF Pages: 5088-5098 Full Text (1010) Reporting Checklist Peer Review File COI Form Open Access

Analgesia in esophagectomy: a narrative review

Minke L. Feenstra, Mark I. van Berge Henegouwen, Markus W. Hollmann, Jeroen Hermanides, Wietse J. Eshuis

PDF Pages: 5099-5111 Full Text (1257) Reporting Checklist Peer Review File COI Form Open Access

Methods for detecting of cardiac troponin I biomarkers for myocardial infarction using biosensors: a narrative review of recent research

Qingzhuo Chen, Wenxin Wu, Ke Wang, Zhijun Han, Chengjian Yang

PDF Pages: 5112-5121 Full Text (1293) Reporting Checklist Peer Review File COI Form Open Access

Case Report: iMDT Corner

Successful repair of acquired intrathoracic nonmalignant tracheoesophageal fistulas using thoracoacromial artery perforator flap through a midsternal incision approach: a report of three cases

Peisong Yuan, Benoit Jacques Bibas, Takuya Nagashima, Hei-Yu Matthew Chen, Camilla Poggi, Fei Chen, Yang Hu

PDF Pages: 5122-5133 Full Text (1002) Reporting Checklist Peer Review File COI Form Open Access

Original Article on Sleep Section¹

Screening practices for obstructive sleep apnea in healthy community people: a Chinese community-based study

Guo Pei, Qiong Ou, Guangliang Shan, Yaoda Hu, Miaochan Lao, Yanxia Xu, Longlong Wang, Jiaoying Tan, Bin Lu

PDF Pages: 5134-5149 Full Text (795) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Review Article on Minimally Invasive Treatment of Pectus Deformities²

Minimally invasive repair of pectus excavatum in adults: a review article of presentation, workup, and surgical treatment

Mohamed R. Aly, Juan M. Farina, Michael M. Botros, Dawn E. Jaroszewski

PDF Pages: 5150-5173 Full Text (1149) Peer Review File COI Form Open Access

Review Article on Why is the Outcome Good? Secrets of Lung Transplantation in Japan³

Roles of respirologists in lung transplantation in Japan: narrative review

Takashi Hirama, Yoshinori Okada

PDF Pages: 5174-5181 Full Text (379) Reporting Checklist Peer Review File COI Form Open Access

Long-term management and outcome of lung transplantation in Japan

Seiichiro Sugimoto, Kei Matsubara, Shin Tanaka, Kentaroh Miyoshi, Megumi Ishihara, Shinichi Toyooka

PDF Pages: 5182-5194 Full Text (818) Peer Review File COI Form Open Access

Integrated cardiothoracic team approach for complex lung transplantation procedures in Japan—current status and future direction

Yasushi Shintani, Soichiro Funaki, Takashi Kanou, Naoko Ose, Toru Kimura, Eriko Fukui, Masato Minami, Shigeru Miyagawa

PDF Pages: 5195-5203 Full Text (528) Peer Review File COI Form Open Access

The history of Japanese lung transplantation: the unique pathway to establishing the program and its initial success

Takeshi Shiraishi, Kensuke Midorikawa, So Miyahara, Ryuichi Waseda, Toshihiko Sato

PDF Pages: 5204-5212 Full Text (418) Peer Review File COI Form Open Access

Roles and practice of living-related lobar lung transplantation

Daisuke Nakajima, Hiroshi Date

PDF Pages: 5213-5220 Full Text (409) Peer Review File COI Form Open Access

Review Article on Extracorporeal Life Support in Thoracic Surgery⁴

Extracorporeal life support as a bridge to lung transplantation: a narrative review

Eleonora Faccioli, Ilhan Inci

PDF Pages: 5221-5231 Full Text (513) Reporting Checklist COI Form Open Access

The role of extracorporeal life support in extended lung resections for non-small cell lung cancer: a narrative review

William Lorenzi, Olaf Mercier

PDF Pages: 5232-5238 Full Text (446) Reporting Checklist COI Form Open Access

Extracorporeal life support use in limited lung function: a narrative review

João Santos Silva, Daniel Cabral, Paulo Almeida Calvinho, Anne Olland, Pierre-Emmanuel Falcoz

PDF Pages: 5239-5247 Full Text (521) Reporting Checklist Peer Review File COI Form Open Access

Extracorporeal membrane oxygenation in the surgical management of large mediastinal masses: a narrative review

Eric M. Wherley, Daniel J. Gross, Dao M. Nguyen

PDF Pages: 5248-5255 Full Text (422) Reporting Checklist Peer Review File COI Form Open Access

Letter to the Editor

The benefits of combining the latest technology in thoracic surgery

Michael R. Gooseman, Vasileios Tentzeris, Michael E. Cowen

PDF Pages: 5256-5257 Full Text (569) Peer Review File COI Form Open Access

Detailed association between hepatic dysfunction and tricuspid valve surgery

Yuki Hida, Teruhiko Imamura

PDF Pages: 5258-5259 Full Text (376) COI Form Open Access

If a job’s worth doing, it’s worth doing well at optimal timing

Mi Hee Lim, Hyung Gon Je

PDF Pages: 5260-5261 Full Text (292) COI Form Open Access

Erratum

Erratum to clinical analysis of hospital acquired mycoplasma pneumoniae infection after cardiac surgery: a case series

Editorial Office

PDF Pages: 5262 Full Text (283) Open Access

Disclosure

1. The series “Sleep Section” was commissioned by the editorial office, Journal of Thoracic Disease without any funding or sponsorship.

2. The series “Minimally Invasive Treatment of Pectus Deformities” was commissioned by the editorial office, Journal of Thoracic Disease without any funding or sponsorship. Erik R. de Loos, Jean H. T. Daemen and Frank-Martin Haecker served as the unpaid Guest Editors for the series.

3. The series “Why Is the Outcome Good? Secrets of Lung Transplantation in Japan” was commissioned by the editorial office, Journal of Thoracic Disease without any funding or sponsorship. Masaaki Sato served as the unpaid Guest Editor for the series.

4. The series “Extracorporeal Life Support in Thoracic Surgery” was commissioned by the editorial office, Journal of Thoracic Disease without any funding or sponsorship. Ilhan Inci served as the unpaid Guest Editor for the series.

Vol 15, No 9 (September 28, 2023): Journal of Thoracic Disease

Editorial